Publikationen 2010

• Ozcetin A, Mutlu S, Bakowsky U
  Archaebacterial tetraetherlipid liposomes
  Methods Mol Biol. 2010;605:87-96

• Ankola DD, Durbin EW, Buxton GA, Schäfer J, Bakowsky U, Kumar MN
  Preparation, characterization and in silico modeling of biodegradable nanoparticles containing cyclosporine A and coenzyme Q10
  Nanotechnology. 2010 Feb 10;21(6):065104
  

• Sitterberg J, Gaspar MM, Ehrhardt C, Bakowsky U
  Atomic force microscopy for the characterization of proteoliposomes
  Methods Mol Biol. 2010;606:351-61.

• Sitterberg J, Ozcetin A, Ehrhardt C, Bakowsky U
  Utilising atomic force microscopy for the characterisation of nanoscale drug delivery systems
  Eur J Pharm Biopharm. 2010 Jan;74(1):2-13

Publikationen 2009

• Merkel OM, Mintzer MA, Sitterberg J, Bakowsky U, Simanek EE, Kissel T
  Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity
  Bioconjug Chem. 2009 Sep;20(9):1799-806

• Nguyen J, Reul R, Betz T, Dayyoub E, Schmehl T, Gessler T, Bakowsky U, Seeger W, Kissel T
  Nanocomposites of lung surfactant and biodegradable cationic nanoparticles improve transfection efficiency to lung cells
  J Control Release. 2009 Nov 16;140(1):47-54

• Trapani A, Sitterberg J, Bakowsky U, Kissel T
  The potential of glycol chitosan nanoparticles as carrier for low water soluble drugs
  Int J Pharm. 2009 Jun 22;375(1-2):97-106

• Packhaeuser CB, Lahnstein K, Sitterberg J, Schmehl T, Gessler T, Bakowsky U, Seeger W, Kissel T
  Stabilization of aerosolizable nano-carriers by freeze-drying
  Pharm Res. 2009 Jan;26(1):129-38

Publikationen 2008

• Nguyen J, Xie X, Neu M, Dumitrascu R, Reul R, Sitterberg J, Bakowsky U, Schermuly R, Fink L, Schmehl T, Gessler T, Seeger W, Kissel T
  Effects of cell-penetrating peptides and pegylation on transfection efficiency of polyethylenimine in mouse lungs
  J Gene Med. 2008 Nov;10(11):1236-46

• Höbel S, Prinz R, Malek A, Urban-Klein B, Sitterberg J, Bakowsky U, Czubayko F, Aigner A
  Polyethylenimine PEI F25-LMW allows the long-term storage of frozen complexes as fully active reagents in siRNA-mediated gene targeting and DNA delivery
  Eur J Pharm Biopharm. 2008 Sep;70(1):29-41

• Gaspar MM, Bakowsky U, Ehrhardt C
  Inhaled Liposomes – Current Strategies and Future Challenges
  J. Biomed. Nanotechnol. 2008 Sep;4(3):245-257
  

• Schäfer J, Sitterberg J,Ehrhardt C, Ravi Kumar MNV, Bakowsky U
  A New Drug Vehicle – Lipid Coated Biodegradable Nanoparticles.
  Advances in Science and Technologies. 2008 Sep;57: 148-153

• Dayyoub E, Sitterberg J, Rothe U and Bakowsky U
  New antibacterial, antiadhesive films based on self assemblies of modified Tetraetherlipids.
  Advances in Science and Technologies. 2008 Sep;57: 188-194

• Germershaus O, Mao S, Sitterberg J, Bakowsky U, Kissel T
  Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro.
  J Control Release. 2008 Jan 22;125(2):145-54

• Cai C, Bakowsky U, Rytting E, Schaper AK, Kissel T
  Charged nanoparticles as protein delivery systems: A feasibility study using lysozyme as model protein
  Eur J Pharm Biopharm. 2008 May;69(1):31-42

• Bakowsky H, Richter T, Kneuer C, Hoekstra D, Rothe U, Bendas G, Ehrhardt C, Bakowsky U
  Adhesion characteristics and stability assessment of lectinmodified liposomes for site-specific drug delivery
  Biochim Biophys Acta. 2008 Jan;1778(1):242-9

Publikationen 2007

• Betz T, Bakowsky U, Müller MR, Lehr CM, Bernhardt I
  Conformational change of membrane proteins leads to shape changes of red blood cells
  Bioelectrochemistry 2007 Jan;70(1):122-126

• Jintapattanakit A, Junyaprasert VB, Mao S, Sitterberg J, Bakowsky U, Kissel T
  Peroral delivery of insulin using chitosan derivatives: A comparative study of polyelectrolyte nanocomplexes and nanoparticles
  Int J Pharm. 2007 Sep 5;342(1-2):240-9

• Westedt U, Kalinowski M, Wittmar M, Merdan T, Unger F, Fuchs J, Schäller S, Bakowsky U, Kissel T
  Poly(vinyl alcohol)-graft-poly(lactideco-glycolide) nanoparticles for local delivery of paclitaxel for restenosis treatment
  J Control Release. 2007 May 14;119(1):41-51

• Bakowsky U, Sitterberg J
  Understanding nanoscale drug delivery systems
  Glatt International Times. 2007;23:19-23

• Christ K, Wiedemann I, Bakowsky U, Sahl HG, Bendas G
  The role of lipid II in membrane binding of and pore formation by nisin analyzed by two combined biosensor techniques.
  Biochim Biophys Acta. 2007 Mar;1768(3):694-704

• Kleemann E, Schmehl T, Gessler T, Bakowsky U, Kissel T, Seeger W
  Iloprost-containing liposomes for aerosol application in pulmonary arterial hypertension: formulation aspects and stability
  Pharm Res. 2007 Feb;24(2):277-87

Publikationen 2006

• Neu M, Sitterberg J, Bakowsky U, Kissel T
  Stabilized Nanocarriers for Plasmids Based Upon Cross-linked Poly(ethylene imine).
  Biomacromolecules. 2006 Dec;7(12):3428-38

• Kneuer C, Ehrhardt C, Radomski MW, Bakowsky U
  Selectins-potential pharmacological targets?
  Drug Discov Today. 2006 Nov;11(21-22):1034-40

• Anabousi S, Kleemann E, Bakowsky U, Kissel T, Schmehl T, Gessler T, Seeger W, Lehr CM, Ehrhardt C
  Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant
  J Nanosci Nanotechnol. 2006 Sep-Oct;6(9-10):3010-6

• Mao S, Neu M, Germershaus O, Merkel O, Sitterberg J, Bakowsky U, Kissel T
  Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly(ethylene imine)-graftpoly(ethylene glycol) block copolymer/SiRNA polyplexes
  Bioconjug Chem. 17: 1209-1218

• Germershaus O, Merdan T, Bakowsky U, Behe M, Kissel T
  Trastuzumab-polyethylenimine-polyethylene glycol conjugates for targeting Her2expressing tumors
  Bioconjug. Chem. 17: 1190-1199
  
  
• Kneuer C, Ehrhardt C, Bakowsky H, Kumar  M.N., Oberle V., Lehr C-M, Hoekstra D, Bakowsky U
  The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: a comparative study
  J. Nanosci. Nanotechnol. 6: 2776-2782.
• Anabousi S, Bakowsky U, Schneider M, Huwer H, Lehr C-M, Ehrhardt C In vitro assessment of transferrin-conjugated liposomes as drug delivery systems for inhalation therapy of lung cancer. Eur. J. Pharm. Sci. 29: 367-374

• Grzelinski M, Urban-Klein B, Martens T, Lamszus K, Bakowsky U, Höbel S, Czubayko F, and Aigner A 2006. RNAi-mediated gene silencing of pleiotrophin (PTN) through PEI-complexed siRNAs in vivo exerts anti-tumoral effects in glioblastoma xenografts. Hum. Gene. Ther. 17: 751-66

• Gutmayer D, Thomann R, Bakowsky U, Schubert R 2006. Synthesis of a Polymer Skeleton at the Inner Leaflet of Liposomal Membranes: Polymerization of Membrane-Adsorbed pH-Sensitive Monomers. Biomacromolecules 7: 1422-1428.

• Werth S, Urban-Klein B, Dai L, Hobel S, Grzelinski M, Bakowsky U, Czubayko F, Aigner A 2006. A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes. J. Control. Rel. 112: 257-270

• Oster C.G., Wittmar M, Bakowsky U, Kissel T. 2006. DNA nano-carriers from biodegradable cationic branched polyesters are formed by a modified solvent displacement method.
  J. Control. Rel. 111: 371-381

• Mao S, Bakowsky U, Jintapattanakit A, Kissel T. 2006. Self-assembled polyelectrolyte nanocomplexes between chitosan derivatives and insulin. J.
  Pharm. Sci. 95: 1035-1048

• Olbrich C, Hauff P, Scholle F, Schmidt W, Bakowsky U, Briel A, Schirner M 2006. The in vitro stability of air-filled polybutylcyanoacrylate microparticles.
  Biomaterials 27: 3549-3559

• Schumacher G, Bakowsky U, Gege C, Schmidt R R , Rothe U, Bendas G 2006. Lessons Learned from Clustering of Fluorinated Glycolipids on Selectin Ligand Function in Cell Rolling.
  Biochemistry 45: 2894-2903

• U Bakowsky 2006. Neue antiadhesive und antibakterielle Katheterbeschichtungen.
  labor&more 5/06: 64-65

• Hariharan S, Bhardwaj V, Bala I, Sitterberg J, Bakowsky U, Ravi Kumar M.N.V 2006. Design of estradiol loaded PLGA nanoparticulate formulations: Apotential oral delivery system for hormone therapy.
  Pharm. Res. 23: 184-195

• M. Sacher, G. Blume, U. Bakowsky, K. Jung. 2006. Antioxidative penetration efficacy of liposomally encapsulated coenzyme Q10.
  Cosmetics SÖFW-Journal 132/ 4-2006: 48-53

• Bakowsky U., C.Ehrhardt, C. Loehbach, P. Li, C.Kneuer, D.Jahn, D.Hoekstra, and C.-M Lehr. 2005.
  Adhesion Molecule-Modified Cardiovascular Prostheses: Characterization of Cellular Adhesion in a Cell Culture Model and by Cellular Force Spectroscopy.
  Adhesion – Current Research and Application ISBN 3-52731263- 3: 157-171

• Merdan T, Kunath K, Petersen H, Bakowsky U, Voigt K.H., Kopecek J, Kissel, T. 2005.
  PEGylation of poly(ethylene imine) affects stability of complexeswith plasmid DNA under in vivo conditions in a dose-dependent manner afterintravenous injection into mice.
  Bioconjug. Chem. 16: 785-792

• I.S. Zuhorn, U. Bakowsky, E.Polushkin, W.H. Visser, M.C.A. Stuart, J.B.F.N.Engberts, D. Hoekstra. 2005.
  Nonbilayer phase of lipoplex – membrane mixturedetermines endosomal escape of genetic cargo and transfection efficiency.
  Molecular Therapy 11: 801-810,

• F. Yu, F. Mücklich, P. Li, H. Shen, S. Mathur, C.-M. Lehr, U. Bakowsky. 2005. In vitro cell response to polymer surface micropatterned by Laser Interference Lithography.
  Biomacromolecules 6:1160-1167

• F. Yu, P. Li, H. Shen, S. Mathur, C.-M. Lehr, U. Bakowsky, F. Mücklich . 2005. Laser Interference Lithography as a new and efficient technique for micropatterning of biopolymer surface.
  Biomaterials 26: 2307-2312

• J. Haas, M. N. V. Ravi Kumar, G. Borchardt, U. Bakowsky, C.-M. Lehr. 2005. Preparation and characterisation of chitosan and trimethyl-chitosan modified PCL nanoparticles as potential DNA carriers.
  AAPS PharmSciTech. 6: E22-E30

• C. Ehrhardt, C. Kneuer, C. Bies, C.-M. Lehr, K.J. Kim, U. Bakowsky. 2005. Salbutamol is actively absorbed across human respiratory epithelial cell layers.
  Pulm. Pharmacol. Ther. 18:165-170

• Anabousi, S., Laue, M., Lehr, C.-M., Bakowsky, U., Ehrhardt, C. 2005. Assessing transferrin modification of liposomes by Atomic Force Microscopy and Transmission Electron Microscopy.
  Eur. J. Pharm. Biopharm. 60: 295-303

• M. N. V. Ravi Kumar, M. Sameti, S. S. Mohapatra, X. Kong, R.F. Lockey, U. Bakowsky, G. Lindenblatt, H. Schmidt, C.-M. Lehr. 2004. Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro & in vivo. J.NanoSci.NanoTech. 4: 876-881.

• Kumar, M.N.V.R., Mohapatra, S.S., Kong, X., Jena, P.K., Bakowsky, U., Lehr, C.M.. 2004 Cationic Poly(lactide-co-glycolide) nanoparticles as efficient in vivo gene transfection agents.
  J. NanoSci. NanoTech. 4: 1-5

• Simon, M., Wittmar, M., Bakowsky, U., Kissel, T. 2004. Self-assembling nanoplexes from insulin and water-soluble branched polyesters, poly[(vinyl-3( diethylamino)-propylcarbamate-co-(vinyl acetate)-co-(vinyl alcohol)]-graft-poly(L- Lactic acid):
  A novel carrier for transmucosal delivery of peptides.
  Bioconjug.Chem. 15: 841-849

• Kumar, M.N.V.R., Bakowsky, U., Lehr, C.M. 2004. Preparation and characterization of cationic PLGA nanospheres as DNA carriers.
  Biomaterials 25: 1771-1777

• C. Ehrhardt, C. Kneuer, U. Bakowsky. 2004. Selectins – an emerging target for drug delivery.
  Adv. Drug Del. Rev. 56: 527-549

• M. N. V. Ravi Kumar, U. Bakowsky, C. M. Lehr. 2004. Nanoparticles as non-viral transfection agents.
  NanoBiotechnology ISBN 3-527-30658-7 : 319-338 

• K. Tabatt, C. Kneuer, M. Sameti, C. Olbrich, R.H. Muller, C.-M. Lehr, U. Bakowsky. 2004. Transfection with different colloidal systems: comparison of solid lipid nanoparticles and liposomes.
  J.Contr. Rel. 97: 321-332

• T. Merdan, J. Callahan, H. Petersen, K. Kunath, u. Bakowsky, P. Kopeckova, T. Kissel, J. Kopecek. 2003. Pegylated Polyethylenimine-Fab’ antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells.
  Bioconjugate Chem. 14: 989-996

• Ping Li, Fayou Yu, Christoph Loehbach, Frank Muecklich, Claus-Michael Lehr and Udo Bakowsky. 2003. New Methods of Laser Ablation Patterning induces Directional Cell Growth.
  IEEE T. NanoBioSci. 2: 138-145

• M. Sameti, G. Bohr, M. N. V. Ravi Kumar, C. Kneuer, U. Bakowsky, M. Nacken, H. Schmidt, C.-M. Lehr. 2003. Stabilisation by freeze-drying of cationically modified silica nanoparticles for gene delivery.
  Int. J. Pharm. 266: 51-60

• C. Daniel, F. Yu, T. F. Mücklich, Recktenwald, U. Bakowsky. 2003. Periodische Mikro-Nano-Strukturierung von polymeren Oberflächen mittels interferierender Laserstrahlen. in: W. Blau, H. Böttcher, Ch. Neinhuis (Hrsg) EFDS-Tagungsband, 4.
  Wörlitzer Workshop “Funktionelle Schichten“: 33-40

• P. Li, C. Ehrhardt, C. Loehbach, C.M. Lehr, U. Bakowsky. 2004. Tissue engineering and surface coating in pharmaceutical nanotechnology.
  Smart materials and Nanotechnologies V, edited by A Lodini, F Rustichelli. 26 - 41

• U. Bakowsky, H. Bakowsky, C. Kneuer, U. Rothe. 2003. Tetraetherlipide von Thermoplasma acidophilum – Herkunft und physikalisch-chemische Eigenschaften.
  Tagungsband zum 11. Heiligenstädter Kolloqium ISBN 3-00011287- 1: 65-72

• U. Bakowsky, C.M. Lehr. 2003. Membranen und Gewebe aus der Retorte.
  Pharmazeutische Zeitung 49: 19-24

• U. Bakowsky, C.M. Lehr. 2003. Nanopartikel als Wirkstoffträger. Pharmazeutische
  Zeitung 47: 17-22