Benzler J, Ganjam GK, Legler K, Stöhr S, Krüger M, Steger J, Tups A. Acute inhibition of central c-Jun N-terminal kinase restores hypothalamic insulin signalling and alleviates glucose intolerance in diabetic mice. J Neuroendocrinol 2013 Jan 10. PMID:23301857
Benzler J, Ganjam GK, Krüger M, Pinkenburg O, Kutschke M, Stöhr S, Steger J, Koch CE, Olkrug R, Schwartz MW, Shepherd PR, Grattan DR, Tups A. Hypothalamic glycogen-synthase-kinase 3β has a central role in the regulation of food intake and glucose metabolism. Biochem J. 2012 Aug 1. PMID:22849606
Koch CE, Ganjam G, Steger J, Legler K, Stöhr S, Schumacher D, Hoggard N, Heldmaier G, Tups A. The dietary flavonoids naringenin and quercetin acutely impair glucose metabolism in rodents possibly via inhibitation of hypotalamic insulin signalling. Br J Nutr. 2012 Aug 1. PMID:22850125
Koch CE, Göddeke S, Krüger M, Tups A. Effect of central and peripheral leucine on energy metabolism in the Djungarian hamster (Phodopus sungorus). J Comp Physiol B. 2012 Jul 29. PMID:22843139
Tups A, Stöhr S, Helwig M, Barrett P, Krol E, Schachtner J, Mercer JG, Klingenspor M. Seasonal leptin resistance is associated with impaired signalling via JAK2- STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein. J Comp. Physiol. B. 2011 Dec 1. PMID: 22198805
Tups A, Anderson GM, Rizwan M, Augustine RA, Chaussade C, Shepherd PR, Grattan DR. Both p110alpha and p110beta isoforms of phosphatidylinositol 3-OH-kinase are required for insulin signalling in the hypothalamus. J Neuroendocrinol. 2010 Mar 2. PMID: 20236230
Tups A. Physiological models of leptin resistance. J Neuroendocrinol. 2009 Nov;21(11):961-71. Epub 2009 Sep 1. Review. PMID: 19732287
Helwig M, Archer ZA, Heldmaier G, Tups A, Mercer JG, Klingenspor M. Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus). J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2009 Jul;195(7):631-42. Epub 2009 Apr 5. PMID: 19347341
Ladyman SR, Tups A, Augustine RA, Swahn-Azavedo A, Kokay IC, Grattan DR. Loss of hypothalamic response to leptin during pregnancy associated with development of melanocortin resistance. J Neuroendocrinol. 2009 May;21(5):449-56. PMID: 19302191
Quennell JH, Mulligan AC, Tups A, Liu X, Phipps SJ, Kemp CJ, Herbison AE, Grattan DR, Anderson GM. Leptin indirectly regulates gonadotropin-releasing hormone neuronal function. Endocrinology. 2009 Jun;150(6):2805-12. Epub 2009 Jan 29. PMID: 19179437
Król E, Tups A, Archer ZA, Ross AW, Moar KM, Bell LM, Duncan JS, Mayer C, Morgan PJ, Mercer JG, Speakman JR. Altered expression of SOCS3 in the hypothalamic arcuate nucleus during seasonal body mass changes in the field vole, Microtus agrestis. J Neuroendocrinol. 2007 Feb;19(2):83-94. PMID: 17214870
Helwig M, Khorooshi RM, Tups A, Barrett P, Archer ZA, Exner C, Rozman J, Braulke LJ, Mercer JG, Klingenspor M. PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus). J Neuroendocrinol. 2006 Jun;18(6):413-25. PMID: 16684131
Tups A, Helwig M, Stöhr S, Barrett P, Mercer JG, Klingenspor M. Photoperiodic regulation of insulin receptor mRNA and intracellular insulin signaling in the arcuate nucleus of the Siberian hamster, Phodopus sungorus. Am J Physiol Regul Integr Comp Physiol. 2006 Sep;291(3):R643-50. Epub 2006 Apr 6. PMID: 16601260
Tups A, Barrett P, Ross AW, Morgan PJ, Klingenspor M, Mercer JG. The suppressor of cytokine signalling 3, SOCS3, may be one critical modulator of seasonal body weight changes in the Siberian hamster, Phodopus sungorus. J Neuroendocrinol. 2006 Feb;18(2):139-45 PMID: 16420283
Tups A, Helwig M, Khorooshi RM, Archer ZA, Klingenspor M, Mercer JG. Circulating ghrelin levels and central ghrelin receptor expression are elevated in response to food deprivation in a seasonal mammal (Phodopus sungorus). J Neuroendocrinol. 2004 Nov;16(11):922-8. PMID: 15584933
Tups A, Ellis C, Moar KM, Logie TJ, Adam CL, Mercer JG, Klingenspor M. Photoperiodic regulation of leptin sensitivity in the Siberian hamster, Phodopus sungorus, is reflected in arcuate nucleus SOCS-3 (suppressor of cytokine signaling) gene expression. Endocrinology. 2004 Mar;145(3):1185-93. Epub 2003 Nov 26. PMID: 14645119
Mercer JG, Tups A. Neuropeptides and anticipatory changes in behaviour and physiology: seasonal body weight regulation in the Siberian hamster. Eur J Pharmacol. 2003 Nov 7;480(1-3):43-50. Review. PMID: 14623349
