Original Publications (1999-2008)

Grgic, I., Paschen, St., Kaistha, B.P., Kaistha, A., Busch, Ch., Si, H., Köhler, K., Elsässer, H.P., Hoyer, J., Köhler, R. Disruption of the Gardoschannel (K_Ca3.1) in mice causes subtle erythrocyte macrocytosis and progressive splenomegaly. Pflügers Arch., 2008 Nov 27. [Epub ahead of print]

Delacour, D., Koch, A., Ackermann, W., Eude-Le Parco, I., Elsässer, H.P., Poirier, F. and Jacob, R. Loss of galectin-3 impairs membrane polarisation of mouse enterocytes in vivo. J Cell Sci 121: 458-465, 2008

Forster, N., Gallinat, S., Jablonska, J., Weiss, S., Elsässer, H.P. and Lutz, W. p300 Protein Acetyltransferase Activity Suppresses Systemic Lupus Erythematosus-Like Autoimmune Disease in Mice. J Immunol,. 178, 6941-6948, 2007

Ertmer, A., Huber, V., Gilch, S., Yoshimori, T., Erfle, V., Duyster, J., Elsässer, H.P. and Schatzl, H.M. The anticancer drug imatinib induces cellular autophagy. Leukemia,21, 936-942, 2007

Schröder, B., Elsässer, H,P., Schmidt, B.and Hasilik, A. Characterisation of lipofuscin-like lysosomal inclusion bodies from human placenta.FEBS Lett, 581, 102-108, 2007

Gebhardt, A., Kosan, Ch., Herkert, B., Möröy, T., Lutz, W., Eilers, M. and Elsässer, H.P. Miz1 is required for hair follicle structure and hair morphogenesis.J Cell Sci 120: 2586-2593, 2007

Krüger, I., Vollmer, M., Simmons, D., Elsässer, H.P., Philipsen, S. and Suske, G. Sp1/Sp3 Compound Heterozygous Mice Are Not Viable: Impaired Erythropoiesis and Severe Placental Defects. Dev Dyn 236: 2235-2244, 2007

Hucl, T., Jesnowski, R., Pfützer, R.H., Elsässer, H.P., Löhr, M. SPINK1 variants in young-onset pancreatic cancer. J Gastroenterol 42: 599, 2007

Kueper, Th., Grune, T., Prahl, St., Lenz, H., Welge, V., Biernoth, T., Vogt, Y., Muhr, G.-M., Gaemlich, A., Jung, T., Boemke, G., Wittern, K.P., Wenck, H., Stäb, F. and Blatt, Th. Vimentin is the specific target in skin glycation: structural prerequisites, functional consequences and role in skin ageing.J Biol Chem 282: 23427-23436, 2007

Lenz, H., Schmidt, M., Welge, V., Kueper, Th, Schlattner, U., Wallimann, Th., Elsässer, H.P., Wittern, K.P., Wenck, H., Stäb, F. and Blatt, Th. Inhibition of cytosolic and mitochondrial creatine kinase by siRNA in HaCaT- and HeLaS3-cells affects cell viability and mitochondrial morphology. Mol Cell Biochem 306: 153-162, 2007

Schröder, B., Wrocklage, Ch., Pan, C., Jäger, R., Kösters, B., Schäfer, H., Elsässer, H.P., Matthias Mann, M. and Andrej Hasilik, A. Integral and Associated Lysosomal Membrane Proteins. Traffic 8:1676-1686, 2007

Biederbick A, Stehling O, Rosser R, Niggemeyer B, Nakai Y, Elsasser HP, Lill R. Role of human mitochondrial Nfs 1 in cytosolic iron-sulfur protein biogenesis and iron regulation. Mol Cell Biol. 26: 5675-5687, 2006.

Lill R, Dutkievicz R, Elsasser HP, Hausmann A, Netz DJ, Pierik AJ, Stehling O, Urzica E, Muehlenhoff U. Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eucaryotes. Biochim Biophys Acta 1763: 652-667, 2006.

Gebhardt A, Frye M, Herold S, Samans B, Watt F, Elsässer HP ,Eilers M. Regulation of keratinocyte proliferation and adhesion by Myc via complex formation with Miz1. J Cell Biol 172; 139-149, 2006

Ünver N, Freyschmidt-Paul P, Hörster S, Wenck H, Stäb F, Blatt T, Elsässer HP. Alterations in the epidermal-dermal melanin axis anf factor XIIIa melanophages in lentigo senilis and aging skin. Br J Dermatol 155: 119-128, 2006

Hale MA, Frye M, Herold S, Samans B, Watt F, Elsässer HP, MacDonald RJ, Hammer RE. PDX1 is required at mid-pancreatic development for the formation of the exocrine pancreas. Dev Biol 286: 225-237, 2005

Lenz H, Schmidt M, Welge V, Schlattner U, Wallimann T, Elsässer HP, Wittern KP, Wenck H, Stäb F, Blatt T. The creatine kinase system in human skin: protective effects of creatine against oxidative and UV damage in vitro and in vivo.J Inv Dermatol 124: 443-52, 2005

Stehling O, Elsässer HP, Brückel B, Mühlenhoff U, Lill R. Iron-sulfur protein maturation in human cells: Evidence for a function of frataxin. Hum Mol Genet 13: 3007-15, 2004

Biederbick A, Rösser R, Storre J, Elsässer HP. The VSFASSQQ motif confers substrate specificity and calcium sensitivity to the intracellular apyrase LALP70. BMC Biochemistry 5: 8, 2004

Gebhardt A, Ackermann W, Ünver N, Elsässer HP . Expression of galectin-3 in the rat pancreas during regeneration from hormone induced pancreatitis. Cell Tiss Res 315: 321-329, 2004

Adhikary S, Karen P, Karsunky H, Beuger V, Lutz W, Elsässer HP, Möröy T and Eilers M. Miz1is required for early embryonic development during gastrulation.Mol Cell Biol 23: 7648-7657, 2003.

Bieber T, Meissner W, Kostin S, Niemann A, Elsässer HP. Intracellular route and transcriptional competence of polyethylenimine-DNA complexes. J Controlled Release 82: 441-454, 2002.

Storre J, Elsässer HP, Fuchs M, Ullmann D, Livingston DM, Gaubatz S. Homeotic transformations of the axial skeleton that accompany a targeted deletion of E2f6.EMBO Report 3: 695-699, 2002

Bieber, T. Elsässer, H.-P: Preparation of a Low Molecular Weight Polyethylenimine for Efficient Cell Transfection. BioTechniques 30:74-81 2001

Niemann A, Baltes J, Elsasser HP: Fluorescence Properties and Staining Behavior of Monodansylpentane, a Structural Homologue of the Lysosomotropic Agent Monodansylcadaverine. J Histochem Cytochem 49:177-186, 2001

Rodel B, Tavassoli K, Karsunky H, Schmidt T, Bachmann M, Schaper F, Heinrich P, Shuai K, Elsasser HP, Moroy T: The zinc finger protein gfi-1 can enhance STAT3 signaling by interacting with the STAT3 inhibitor PIAS3. Embo J 19:5845-5855, 2000

Westphalen S, Kotulla G, Kaiser F, Krauss W, Werning G, Elsasser HP, Nagy A, Schulz KD, Grundker C, Schally AV, et al.: Receptor mediated antiproliferative effects of the cytotoxic LHRH agonist AN-152 in human ovarian and endometrial cancer cell lines. Int J Oncol 17:1063-1069, 2000.

Fernandez Pujol B, Lucibello FC, Gehling UM, Lindemann K, Weidner N, Zuzarte ML, Adamkiewicz J, Elsasser HP, Muller R, Havemann K: Endothelial-like cells derived from human CD14 positive monocytes. Differentiation 65:287-300, 2000.

Biederbick A, Kosan C, Kunz J, Elsasser HP: First apyrase splice variants have different enzymatic properties. J Biol Chem 275:19018-19024, 2000.

Bouwman P, Gollner H, Elsasser HP, Eckhoff G, Karis A, Grosveld F, Philipsen S, Suske G: Transcription factor Sp3 is essential for post-natal survival and late tooth development. Embo J 19:655-661, 2000.

Niemann A, Takatsuki A, Elsasser HP: The lysosomotropic agent monodansylcadaverine also acts as a solvent polarity probe. J Histochem Cytochem 48:251-258, 2000.

Fischer D, Bieber T, Li Y, Elsasser HP, Kissel T: A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res 16:1273-1279, 1999.

Biederbick A, Rose S, Elsasser HP: A human intracellular apyrase-like protein, LALP70, localizes to lysosomal/autophagic vacuoles. J Cell Sci 112:2473-2484, 1999.