PUBLICATIONS

2012

Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology.

Berkel S, Tang W, Treviño M, Vogt M, Obenhaus HA, Gass P, Scherer SW, Sprengel R, Schratt G, Rappold GA.

Hum Mol Genet. 2012 Jan 15;21(2):344-57. Epub 2011 Oct 12.

2011

The dopamine-regulated microRNA, miR-181a, controls GluA2 surface expression in hippocampal neurons.

Saba R, Störchel PH, Aksoy-Aksel A, Kepura F, Lippi G, Plant TD, Schratt GM.

Mol Cell Biol. 2011 Dec 5. [Epub ahead of print]

Releasing a tiny molecular brake may improve memory.

Fiore R, Schratt G.

EMBO J. 2011 Oct 19;30(20):4116-8. doi: 10.1038/emboj.2011.356. No abstract available.

Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology.

Lippi G, Steinert JR, Marczylo EL, D’Oro S, Fiore R, Forsythe ID, Schratt G, Zoli M, Nicotera P, Young KW.

J Cell Biol. 2011 Sep 19;194(6):889-904.

microRNAs in neurons: manifold regulatory roles at the synapse.

Siegel G, Saba R, Schratt G.

Curr Opin Genet Dev. 2011 Aug;21(4):491-7. Epub 2011 May 9. Review.

MicroRNA function in the nervous system.

Fiore R, Khudayberdiev S, Saba R, Schratt G.

Prog Mol Biol Transl Sci. 2011;102:47-100. Review.

2010

Not miR-ly aging: SIRT1 boosts memory via a microRNA-dependent mechanism.

Bicker S, Schratt G.

Cell Res. 2010 Nov;20(11):1175-7. Epub 2010 Sep 7. No abstract available.

MicroRNAs in neuronal development, function and dysfunction.

Saba R, Schratt GM.

Brain Res. 2010 Jun 18;1338:3-13. Epub 2010 Apr 7. Review.

Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs.

Krol J, Busskamp V, Markiewicz I, Stadler MB, Ribi S, Richter J, Duebel J, Bicker S, Fehling HJ, Schübeler D, Oertner TG, Schratt G, Bibel M, Roska B, Filipowicz W.

Cell. 2010 May 14;141(4):618-31.

Recombinant Adeno-Associated Virus-Mediated microRNA Delivery into the Postnatal Mouse Brain Reveals a Role for miR-134 in Dendritogenesis in Vivo.

Christensen M, Larsen LA, Kauppinen S, Schratt G.

Front Neural Circuits. 2010 Jan 12;3:16.

2009

microRNA involvement in developmental and functional aspects of the nervous system and in neurological diseases.

Christensen M, Schratt GM.

Neurosci Lett. 2009 Dec 4;466(2):55-62. Epub 2009 Apr 23. Review.

microRNAs at the synapse.

Schratt G.

Nat Rev Neurosci. 2009 Dec;10(12):842-9. Epub 2009 Nov 4. Review.

MicroRNA as modulators of neuronal responses.

Khudayberdiev S, Fiore R, Schratt G.

Commun Integr Biol. 2009 Sep;2(5):411-3.

A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis.

Siegel G, Obernosterer G, Fiore R, Oehmen M, Bicker S, Christensen M, Khudayberdiev S, Leuschner PF, Busch CJ, Kane C, Hübel K, Dekker F, Hedberg C, Rengarajan B, Drepper C, Waldmann H, Kauppinen S, Greenberg ME, Draguhn A, Rehmsmeier M, Martinez J, Schratt GM.

Nat Cell Biol. 2009 Jun;11(6):705-16. Epub 2009 May 24.

Fine-tuning neural gene expression with microRNAs.

Schratt G.

Curr Opin Neurobiol. 2009 Apr;19(2):213-9. Epub 2009 Jun 17. Review.

Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels.

Fiore R, Khudayberdiev S, Christensen M, Siegel G, Flavell SW, Kim TK, Greenberg ME, Schratt G.

EMBO J. 2009 Mar 18;28(6):697-710. Epub 2009 Feb 5.

2008

microRNAs: tiny regulators of synapse function in development and disease.

Bicker S, Schratt G.

J Cell Mol Med. 2008 Sep-Oct;12(5A):1466-76. Epub 2008 Jul 8. Review.

MicroRNA function in neuronal development, plasticity and disease.

Fiore R, Siegel G, Schratt G.

Biochim Biophys Acta. 2008 Aug;1779(8):471-8. Epub 2008 Jan 14. Review.

2007

MicroRNAs in synapse development: tiny molecules to remember.

Fiore R, Schratt G.

Expert Opin Biol Ther. 2007 Dec;7(12):1823-31. Review.

MicroRNAs in vertebrate synapse development.

Fiore R, Schratt G.

ScientificWorldJournal. 2007 Nov 2;7:167-77. Review.

Noncoding RNAs in the brain.

Satterlee JS, Barbee S, Jin P, Krichevsky A, Salama S, Schratt G, Wu DY.

J Neurosci. 2007 Oct 31;27(44):11856-9. Review.

2006

Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia.

Gazda HT, Grabowska A, Merida-Long LB, Latawiec E, Schneider HE, Lipton JM, Vlachos A, Atsidaftos E, Ball SE, Orfali KA, Niewiadomska E, Da Costa L, Tchernia G, Niemeyer C, Meerpohl JJ, Stahl J, Schratt G, Glader B, Backer K, Wong C, Nathan DG, Beggs AH, Sieff CA.

Am J Hum Genet. 2006 Dec;79(6):1110-8. Epub 2006 Nov 2.

A brain-specific microRNA regulates dendritic spine development.

Schratt GM, Tuebing F, Nigh EA, Kane CG, Sabatini ME, Kiebler M, Greenberg ME.

Nature. 2006 Jan 19;439(7074):283-9. Erratum in: Nature. 2006 Jun 15;441(7095):902.

2004

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF.

Philippar U, Schratt G, Dieterich C, Müller JM, Galgóczy P, Engel FB, Keating MT, Gertler F, Schüle R, Vingron M, Nordheim A.

Mol Cell. 2004 Dec 22;16(6):867-80.

BDNF regulates the translation of a select group of mRNAs by a mammalian target of rapamycin-phosphatidylinositol 3-kinase-dependent pathway during neuronal development.

Schratt GM, Nigh EA, Chen WG, Hu L, Greenberg ME.

J Neurosci. 2004 Aug 18;24(33):7366-77.

SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development.

Schratt G, Philippar U, Hockemeyer D, Schwarz H, Alberti S, Nordheim A.

EMBO J. 2004 Apr 21;23(8):1834-44. Epub 2004 Apr 1.

2003

The kinase MSK1 is required for induction of c-fos by lysophosphatidic acid in mouse embryonic stem cells.

Schuck S, Soloaga A, Schratt G, Arthur JS, Nordheim A.

BMC Mol Biol. 2003 May 26;4:6. Epub 2003 May 26.

2002

Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

Wang DZ, Li S, Hockemeyer D, Sutherland L, Wang Z, Schratt G, Richardson JA, Nordheim A, Olson EN.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14855-60. Epub 2002 Oct 23.

Serum response factor is crucial for actin cytoskeletal organization and focal adhesion assembly in embryonic stem cells.

Schratt G, Philippar U, Berger J, Schwarz H, Heidenreich O, Nordheim A.

J Cell Biol. 2002 Feb 18;156(4):737-50. Epub 2002 Feb 11.

******

Review articles:

Fiore R., Schratt G (2011) Releasing a tiny molecular brake may improve memory EMBO J. 30(20):4116-8.

Fiore R., Khudayberdiev, S., Saba, R. and Schratt, G. (2011) microRNA function in the nervous system. Prog Mol Biol Transl Sci. 102:47-100.

Siegel, G., Saba R. and Schratt G., (2011) microRNAs in neurons: manifold regulatory roles at the synapse. Curr Opin Genet Dev. 21(4):491-7.

Bicker, S. and Schratt, G. (2010) Not miR-ly aging: SIRT1 boosts memory via a microRNA-dependent mechanism. Cell Res. 20(11):1175-7.

Saba, R. and Schratt G. (2010) MicroRNAs in neuronal development, function and dysfunction. Brain Res. 1338:3-13.

Schratt, G. (2009) microRNAs at the synapse. Nat Rev Neurosci. 10(12): 842-9.

Khudayberdiev S., Fiore R. and Schratt G. (2009) microRNAs as modulators of neuronal responses. Commun Integr Biol. 2(5): 411-3.

Schratt G. (2009) Fine-tuning neural gene expression with microRNAs. Curr. Op. Neurobiol., 19(2):213-9.

Christensen, M. and Schratt, G. (2009) microRNA involvement in developmental and functional aspects of the nervous system and in neurological diseases. Neurosci. Lett. 4;466(2):55-62.

Bicker S. and Schratt G. (2008) microRNAs: Tiny regulators of synapse function in development and disease. J Cell Mol Med., 12(5A):1466-76.

Fiore R., Siegel G. and Schratt G. (2008) microRNA function in neuronal development, plasticity and disease. Biochim Biophys Acta 1779(8): 471-8.

Fiore R. and Schratt G. (2007) microRNAs in vertebrate synapse development. The Scientific World Journal 7: 167-77.

Fiore R. and Schratt G. (2007) microRNAs in synapse development: Tiny molecules to remember? Expert Opinion in Biological Therapies 7(12): 1823-31.

Satterlee, J., Barbee, S., Jin, P., Krichevsky, A., Salama, S., Schratt, G. and Wu, D.Y. (2007) Non-coding RNAs in the Brain. J. Neurosci 27(44): 11856-9.

Schratt G. (2002). Der Transkriptionsfaktor SRF. Biospektrum 8(1):66-7.

Book chapters:

Schratt G. and Greenberg M.E. MicroRNA function in the nervous system. In: MicroRNAs: From Basic Science to Disease Biology, ed. Krishnarao Appasani. Cambridge University Press.