External group Prof. Dr. Jan ter Meulen
Prof. Dr. Jan ter Meulen
Executive Director Vaccine Research
Merck Research Laboratories, WP16-100
770 Sumneytown Pike, PO Box 4
West Point, PA 19486, USA
Fields of activity:
- Epidemiology of Hanta and Lassa virus infections in Guinea, West Africa
- Industrial vaccine research (Merck Research Laboratories)
Epidemiology of Hanta and Lassa virus infections in Guinea, West Africa
Description of scientific projects:
Hantaviruses, members of the family Bunyaviridae, are emerging viruses causing two life-threatening human zoonoses; hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The viruses are transmitted from animal reservoirs to humans. Based on the very recent evidence of hantaviruses in rodents and shrews in Guinea, West Africa (Sangassou and Tanganya virus), we participate in a joint project of German and African universities to study the occurrence of hantavirus disease and the biodiversity of hantaviruses and their natural animal reservoirs in West Africa. Moreover, specific diagnostic approaches are being developed for newly detetced African hantaviruses. These efforts will result in capacity building for the detection and characterization of hantaviruses and other emerging zoonotic viruses in Guinea and to the development of virus-diagnostic and public health expertise for the control of rodent-borne zoonotic infections. The project is funded by the German Research Foundation (KR1293/9-1) and coordinated by Prof. Detlev Kruger from the Institute of Virology, Charite, Berlin.
In addition, data from our epidemiological studies on Lassa fever carried out between 2000 and 2006 are still being analyzed and published.
- Dr. Lamine Koivogui
National Institute of Public Health Guinea
BP 5680, Conakry
Republic of Guinea
- D. H. Kruger, M.D., Ph.D.
Professor and ChairmanInstitute of Med. Virology
University Hospital Charité