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Publications

Zulfiqar S, Garg P, Nieweg K
Contribution of astrocytes to metabolic dysfunction in the Alzheimer's disease brain.
Biol Chem. 2019 400(9): 1113-1127 
doi: 10.1515/hsz2019-0140

Klapper SD, Garg P, Dagar S, Lenk K, Gottmann K, Nieweg K 
Astrocyte lineage cells are essential for functional neuronal differentiation and synapse maturation in human iPSC-derived neural networks.
Glia 2019 67(10): 1893-1909 
doi: 10.1002/glia.23666

Zulfiqar S, Fritz B, Nieweg K
Episomal plasmid-based generation of an iPSC line from a 79-year-old individual carrying the APOE4/4 genotype: i11001.
Stem Cell Res. 2016 17(3): 544-546
doi: 10.1016/j.scr.2016.09.023

Zulfiqar S, Fritz B, Nieweg K
Episomal plasmid-based generation of an iPSC line from an 83-year-old individual carrying the APOE4/4 genotype: i10984.
Stem Cell Res. 2016 17(3): 523-525
doi: 10.1016/j.scr.2016.09.017

Hennicke T, Nieweg K, Brockmann N, Kassack MU, Gottmann K, Fritz G 
mESC-based in vitro differentiation models to study vascular response and functionality following genotoxic insults.
Toxicol Sci. 2015 144(1): 138-50
doi: 10.1093/toxsci/kfu264

Nieweg K, Andreyeva A, van Stegen B, Tanriöver G, Gottmann K 
Alzheimer's disease-related amyloid-beta induces synaptotoxicity in human iPS cell-derived neurons.
Cell Death Dis. 2015 Apr 2; 6:e1709.
doi: 10.1038/cddis.2015.72

Leschik J, Eckenstaler R, Nieweg K, Lichtenecker P, Brigadski T, Gottmann K, Leßmann V, Lutz B
Embryonic stem cells stably expresssing BDNF-GFP exhibit a BDNF-release-dependent enhancement of neuronal differentiation
J Cell Sci. 2013 126(21): 5062-73
doi: 10.1242/jcs.135384

Pielarski KN, van Stegen B, Andreyeva A, Nieweg K, Jüngling K, Redies C, Gottmann K
Asymmetric N-cadherin expression results in synapse dysfunction, synapse elimination, and axon retraction in cultured mouse neurons.
PLoS One 2013 8(1):e54105
doi: 10.1371/journal.pone.0054105

Andreyeva A, Nieweg K, Horstmann K, Klapper S, Müller-Schiffmann A, Korth C, Gottmann K (2012)
C-terminal fragment of N-cadherin accelerates synapse destabilization by amyloid-β.
Brain 135(7):2140-54
doi: 10.1093/brain.aws120

Nieweg K, Schaller H, Pfrieger FW (2009)
Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats.
J Neurochem. 109(1):125-34
doi:10.1111/j.1471-4159.2009.05917.x.

Göritz C, Thiebaut R, Tessier LH, Nieweg K, Moehle C, Buard I, Dupont JL, Schurgers LJ, Schmitz G, Pfrieger FW (2007) Glia-induced neuronal differentiation by transcriptional regulation.
Glia 55(11):1108-22
doi: 10.1002/glia.20531

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