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SUMMARY:Prof. Khaled A. Selim\, Heinrich Heine University Düsseldorf: Bei
 ng lazy is not always bad: Cyclic di-AMP signaling in cyanobacteria
DTSTART;TZID=Europe/Berlin:20251021T090000
DTEND;TZID=Europe/Berlin:20251021T100000
DTSTAMP:20260407T052956Z
UID:c11b55185a4f44489296a0fe80dcc320@www.uni-marburg.de
CATEGORIES:()
CREATED:20241205T125047Z
DESCRIPTION:https://www.uni-marburg.de/en/synmikro/grk2937/whats-on/dates-
 and-events/grk2937_speaker-series_khaled-selim\nSpeaker Series. Abstract: 
 Because of their photosynthesis-dependent lifestyle\, cyanobacteria evolve
 d sophisticated regulatory mechanisms to adapt to oscillating day-night me
 tabolic changes. How they coordinate the metabolic switch between autotrop
 hic and glycogen-catabolic metabolism in light and darkness is poorly unde
 rstood. Recently\, we discovered that the second messenger c-di-AMP is imp
 licated in diurnal regulation. The carbon-sensor protein SbtB was identifi
 ed as a major c-di-AMP receptor. Adding to its cellular functions catalog\
 , for first time\, we show also that c-di-AMP influences on nitrogen metab
 olism\, implying new cellular roles for c-di-AMP. Additionally\, we found 
 that the cyanobacterial pilus biogenesis and natural competence are regula
 ted by c-di-AMP/c-di-GMP and showed that the ComFB signaling protein is a 
 novel c-di-NMP-receptor protein\, widespread in bacterial phyla\, and requ
 ired for DNA uptake.
LAST-MODIFIED:20251006T104633Z
LOCATION:SYNMIKRO Lecture Hall
URL:https://www.uni-marburg.de/en/synmikro/grk2937/whats-on/dates-and-even
 ts/grk2937_speaker-series_khaled-selim
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