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Sie sind hier:» Universität » Psychologie » Forschung » Neurowissenschaften » Mitwirkende » Medizin » Kinscherf
Prof. Dr. Ralf Kinscherf  

Philipps-Universität Marburg, Fachbereich Medizin,

Institut für Anatomie und Zellbiologie, Medizinische Zellbiologie

Robert-Koch-Straße 8 35039 Marburg

Phone: +49 6421 – 2866245

Fax: +49 6421 – 2868983

Email: ralf.kinscherf@staff.uni-marburg.de

https://www.uni-marburg.de/fb20/anatomie/medzellbio/

 Kinscherf-Bild

Research focus
Molecular and cellular mechanisms of neurodegenerative diseases (e.g. Alzheimer) and stroke: in vitro/in vivo; apoptosis/inflammation signal transduction of involved cells; role of (ox)LDL; mice models; amino acid analyses of plasma and cerebrospinal fluid in men and mice;


Techniques

•    2100 Bioanalyzer (Microfluids Chip Electrophoresis): RNA, DNA, Protein analysis

•    Computer-assisted morphometry

•    Light and fluorescence microscopy

•    ELISA

•    (Immuno)electronmicroscopy

•    Electrophoresis

•    (Immuno) histochemistry/cytochemistry

•    In situ-hybridization (non-radioactive, incl. generation of probes)

•    In vivo real-time contrast-enhanced ultrasound of sceletal muscle

•    Conventional histology

•    Laser-microdissection

•    Northern-, Western Blot

•    Plasma-aminoacid-analysis

•    Quantitative real-time RT PCR

•    Protein purification

•    Cell fractionation

•    Cell culture


Publications (10 selected Publications since 2006)

1. Bonaterra GA, Zügel S, Thogersen J, Walther SA, Haberkorn U, Strelau J, Kinscherf R (2012).Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury. J Am Heart Assoc 1 (6). Epub 2012 Dec 19.

2. Kassner SS, Schöttler S, Bonaterra GA, Stern-Sträter J, Sommer U, Hormann K, Kinscherf R*, Gössler UR* (2011). Proinflammatory and proadhesive activation of lymphocytes and macrophages in sudden sensorineural hearing loss. Audiol Neurootol 16(4): 254-62. [*both are senior authors]

3. Kassner SS, Schöttler S, Bonaterra GA, Stern-Sträter J, Hormann K, Kinscherf R*, Gössler UR* (2011). Proinflammatory activation of peripheral blood mononuclear cells in patients with vestibular neuritis. Audiol Neurootol 16(4): 254-62. [*both are senior authors]

4. Kaiser E, Schoenknecht P, Kassner S, Hildebrandt W, Kinscherf R, Schroeder J (2010). Cerebrospinal fluid concentrations of functionally important amino acids and metabolic compounds in patients with mild cognitive impairment and Alzheimer´s desease. Neurodegener Dis 7(4): 251-259.

5. Kassner SS, Kollmar R, Bonaterra GA, Hildebrandt W, Schwab S, Kinscherf R (2009). The early immunological response to acute ischemic stroke: differential gene expression in Subpopulations of mononuclear cells. Neuroscience 160(2): 394-401.

6. Enderlin M, Kleinmann EV, Struyf S, Buracchi C, Vecchi A, Kinscherf R, Kiessling F, Paschek S, Sozzani S, Rommelaere J, Cornelis JJ, van Damme J, Dinsart C (2009). TNF-α and the IFN-g -inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act insynergy to induce antitumor effects in mouse glioblastoma. Cancer Gene Therapy 16(2): 149-60.

7. Kassner SS, Bonaterra GA, Kaiser E, Hildebrandt W, Metz J, Schröder J, Kinscherf R (2008). Novel systemic markers for patients with Alzheimer disease? – A pilot study. Curr Alz Res 5(4): 358-366.

8. Bonaterra GA, Hildebrandt W, Bodens A, Sauer R, Dugi KA, Deigner HP, Turcanu D, Heinle H, Dröge W, Metz J, Kinscherf R (2007). Increased gene expression of scavenger receptors and proinflammatory markers in peripheral blood mononuclear cells of hyperlipidemic males. J Mol Med 85(2): 181-90.

9. Kreusser M, Haass M, Buss SJ, Hardt SE, Gerber SH, Kinscherf R, Katus HA, Backs J (2006). Injection of nerve growth factor into stellate ganglia improves norepinephrine reuptake into failing hearts. Hypertension 47(2): 209-15.

10. Kristen AV, Kreusser M, Lehmann L, Kinscherf R, Katus HA, Haass M, Backs J (2006). Preserved Norepinephrine Reuptake but Reduced Sympathetic Nerve Endings in Hypertrophic Volume-Overloaded Rat Hearts. J Cardiac Failure 12(7): 577-83.

 

 

 

Zuletzt aktualisiert: 09.12.2013 · Busses

 
 
 
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