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Markus Wöhr, PhD  

Philipps-University of Marburg, Faculty of Psychology,

Experimental and Physiological Psychology, Behavioral Neuroscience,

Gutenbergstr. 18, 35037 Marburg

Phone: +49 6421 – 2823612, Fax: +49 6421 – 2823610

Email: markus.woehr@uni-marburg.de

Homepage

 Woehrbild

Research focus
Biological mechanisms underlying social behavior and communication in rodents (e.g. ultrasonic vocalizations); genetic and environmental risk factors (e.g. Neuroligin/Shank genes and viral infection/stress) for neurodevelopmental and affective disorders (e.g. autism/schizophrenia and anxiety/depression); drugs of abuse (e.g. amphetamine and morphine); learning and memory (e.g. social fear learning).

Techniques

-    Behavioral phenotyping (e.g. affective and social behavior and communication) of rodent models for neuropsychiatric disorders (e.g. autism/schizophrenia and anxiety/depression)

-    Characterization of genetically-modified rodents (e.g. PCR and ELISA)

-    Immunohistochemical measurement of brain activity (i.e. immediate early genes) and neuronal plasticity (i.e. neurogenesis)

-    In-vivo psychopharmacology (e.g. serotonin, dopamine, and opioids)

-    Neurotransmitter-specific neurotoxic lesions (e.g. 6-OHDA)

 

Publications (10 selected Publications since 2012)

1. Seffer D, Rippberger H, Schwarting RKW, Wöhr M (2015). Pro-social 50-kHz ultrasonic communication in rats: Post-weaning but not post-adolescent social isolation leads to social impairments – phenotypic rescue by re-socialization. Frontiers in Behavioral Neuroscience 9:102.

2. Valluy J, Bicker S, Aksoy-Aksel A, Lackinger M, Sumer S, Fiore R, Wüst T, Seffer D, Metge F, Dietrich C, Wöhr M, Schwarting RKW, Schratt G (2015). A coding-independent function of an alternative Ube3a transcript during neuronal development. Nature Neuroscience 18:666-673.

3. Mosienko M, Beis D, Alenina N, Wöhr M (2015). Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin. Molecular Autism 6:e13.

4. Wöhr M, Orduz D, Gregory P, Moreno H, Khan U, Vörckel KJ, Wolfer DP, Welzl H, Gall D, Schiffmann S, Schwaller B (2015). Lack of parvalbumin in mice leads to behavioral deficits relevant to all human autism core symptoms and related neural morpho-functional abnormalities. Translational Psychiatry 5:e525.

5. Wöhr M, Rippberger H, Schwarting RKW, van Gaalen M (2015). Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats. Psychopharmacology 232:1817-1829.

6. Lukas M & Wöhr M (2015). Endogenous vasopressin, innate anxiety, and the emission of pro-social 50-kHz ultrasonic vocalizations during social play behavior in juvenile rats. Psychoneuroendocrinology, 56, 35-44.

7. Willuhn I, Tose A, Wanat MJ, Hart AS, Hollon NG, Phillips PEM, Schwarting RKW, Wöhr M (2014) Phasic dopamine release in the nucleus accumbens in response to pro-social 50-kHz ultrasonic vocalizations in rats. The Journal of Neuroscience 34:10616-10623.

8. Wöhr M (2014) Ultrasonic vocalizations in Shank mouse models for autism spectrum disorders: Detailed spectrographic analyses and developmental profiles. Neuroscience and Biobehavioral Reviews 43:199-212.

9. Wöhr M, Schwarting RKW (2012) Testing social acoustic memory in rats: Effects of stimulus configuration and long-term memory on the induction of social approach behavior by appetitive 50-kHz ultrasonic vocalizations. Neurobiology of Learning and Memory 98:154-164.

10. Yee N, Schwarting RKW, Fuchs E, Wöhr M (2012) Increased affective ultrasonic communication during fear learning in adult male rats exposed to maternal immune activation. Journal of Psychiatry Research 46:1199-1205.




 

 

Zuletzt aktualisiert: 13.01.2016 · Busses

 
 
 
Fb. 04 - Psychologie

Fb. 04 - Psychologie, Gutenbergstraße 18, 35032 Marburg
Tel. +49 6421/28-23675, Fax +49 6421/28-26949, E-Mail: dekanpsy@staff.uni-marburg.de

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