Hauptinhalt

"Ocular Drug Delivery - Eye on Innovation"

Prof. Dr. llva Rupenthal University of Auckland, New Zealand

Veranstaltungsdaten

Abstract
While the eye is readily accessible from the outside of the body, it is a rather isolated organ with a number of barriers and elimination mechanisms in place to protect it from the environment, rendering efficient drug delivery to the ocular tissues difficult. This presentation will give an overview of the research performed within the Buchanan Ocular Therapeutics Unit (BOTU) including the investigation of novel therapeutics and innovative drug delivery systems for the management of dry eye, diabetic retinopathy and age-related macular degeneration. Topics will include specific tissue targeting approaches using cell penetrating peptides and coated nanoparticles, the use of physical forces such as ultrasound to overcome the physiological barriers as weil as a number of in vitro, ex vivo and in vivo models to adequately test such systems.

Biography
Associate Professor llva Rupenthal, a Pharmacy graduate from the Philipps University of Marburg, is the inaugural Director of the Buchanan Ocular Therapeutics Unit (BOTU), Department of Ophthalmology, University of Auckland, New Zealand, which aims to translate ocular therapeutic related scientific research into the clinical setting, whether pharmaceutical, cell or technology based. llva has over 16 years of experience in ocular delivery system development and evaluation showcased by over 70 peer-reviewed papers and 3 provisional patents. She received the 2016 Health Research Council 25th Anniversary Emerging Researcher Excellence Award as well as a 2014 University Early Career Research Excellence Award with over $5.6 million in funding received so far. In her spare time, llva likes to enjoy the beautiful New Zealand Ol!tdoors, so you can either find her relaxing on the beach or hiking in the mountains.
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