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The Marburger Neurodynamics Group - Project Overview 

Connecting Theories, Models, and Experiments
for Life Science Research and Education

this is the title of an interdisciplinary symposium at the Physiological Institute in Marburg

(June 8 -10, 2017) program 


and also could be a headline to describe the main interests and current activities of the Marburg Neurodynamics Group towards a better understanding of integrative functions of

-  neuronal coding and information processing,

-  control of autonomic functions; e.g. sleep-wake cycles and stress (HPA) axis

-  and their relations to consciousness and psychiatric disorders

with particular focus on the impact of nonlinear dynamics, chaos and noise


Currently, the focus our work is laid on the development of computer models:

-  we are developing computer simulations for research

-  we are developing computer simulations for teaching

-  and we are teaching how to develop computer simulations


everything on the background of our experience from 

electrophysiological experiments and clinical studies


Main Current Activities:

Virtual Physiology  

Computer Laboratories for Teaching (www.virtual-physiology.com)

Virtual computer laboratories for experimentation almost like in the real world towards a thorough understanding of biological functions – far beyond conventional teaching tools  


Nonlinear Systems, Noise and Diversity

Data Analysis and Nonlinear Systems Theory, Chaos and Co-operative Noise Effects

Elucidating co-operative effects of nonlinear dynamics and " noise" in comparison of experimental data and computer simulations

Cognitive Functions and Consciousness

Determinism, Randomness and the Question of the Free Will

Theories of co-operative effects of nonlinear dynamics with randomness (neuronal diversity, channel noise) in neuronal decision making developed on the basis of experimental data and mathematical simulations



Sensory Encoding

Stimulus Transduction in Thermo- and Electrosensitive Skin Receptors

Experiments beyond the laboratory rat also describing, for example, the exquisite sensitivity of sharks, boa constrictor and vampire bats thereby elucidating particular impact of subthreshold oscillations and noise


Hypothalamic Neurons

Nonlinear Mechanisms in the Control of Autonomic Functions 

Elucidating neuronal information processing taking advantage of impulse pattern alterations based on nonlinear dynamics modulated by multiple stimulus inputs.


Neuron Models

Concepts and Models of Temperature Transduction – beyond TRP channels

Oscillations, chaos and noise: complex neuronal dynamics of temperature transduction simulated with simplified Hodgkin-Huxley type equations in excellent agreement with the experimental data 



Models of Autonomic Functions

Modeling Neuronal Control of Sleep-Wake Cycles and Cortisol Release

Connecting recent experimental and clinical data for mathematical simulations towards a better understanding of the neuronal control sleep-wake-cycles and cortisol realease (HPA-axis).


Psychiatry Models

Modeling Vulnerability and Disease Progression of Bipolar Disorders

Progression of psychiatric disorders simulated in remarkable details with disturbances of autonomous nonlinear feedback systems.



Zuletzt aktualisiert: 23.05.2017 · Susanne Bamerny

Fb. 20 - Medizin

Institut für Physiologie und Pathophysiologie, Deutschhausstraße 1-2, D-35037 Marburg
Tel. +49 6421/28-66495, Fax +49 6421/28-68960, E-Mail: bamerny@staff.uni-marburg.de

URL dieser Seite: https://www.uni-marburg.de/fb20/physiologie/ags/braun/forschung

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