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Publikationen der AG Oberwinkler


2020

The structural basis for an on-off switch controlling Gbetagamma-mediated inhibition of TRPM3 channels
Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J
Proc Natl Acad Sci U S A 117(46):29090-29100

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides
Perniss A, Liu S, Boonen B, Keshavarz M, Ruppert AL, Timm T, Pfeil U, Soultanova A, Kusumakshi S, Delventhal L, Aydin Ö, Pyrski M, Deckmann K, Hain T, Schmidt N, Ewers C, Günther A, Lochnit G, Chubanov V, Gudermann T, Oberwinkler J, Klein J, Mikoshiba K, Leinders-Zufall T, Offermanns S, Schütz B, Boehm U, Zufall F, Bufe B, Kummer W
Immunity 52(4):683-699

Advillin is a tuft cell marker in the mouse alimentary tract
Ruppert AL, Keshavarz M, Winterberg S, Oberwinkler J, Kummer W, Schütz B
J Mol Histol 51(4):421-435


2018

Rationalizing Steroid Interactions with Lipid Membranes: Conformations, Partitioning, and Kinetics
Atkovska K, Klingler J, Oberwinkler J, Keller S, Hub JS
ACS Cent Sci
4(9):1155-1165

A126 in the active site and TI167/168 in the TI loop are essential determinants of the substrate specificity of PTEN
Leitner MG, Hobiger K, Mavrantoni A, Feuer A, Oberwinkler J, Oliver D, Halaszovich CR
Cell Mol Life Sci 75(22):4235-4250

Ca2+-dependent regulation and binding of calmodulin to multiple sites of Transient Receptor Potential Melastatin 3 (TRPM3) ion channels
Przibilla J, Dembla S, Rizun O, Lis A, Jung M, Oberwinkler J, Beck A, Philipp SE
Cell Calcium 73:40-52


2017

Anti-nociceptive action of peripheral mu-opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels
Dembla S, Behrendt M, Mohr F, Goecke C, Sondermann J, Schneider FM, Schmidt M, Stab J, Enzeroth R, Leitner MG, Nuñez-Badinez P, Schwenk J, Nürnberg B, Cohen A, Philipp SE, Greffrath W, Bünemann M, Oliver D, Zakharian E, Schmidt M, Oberwinkler J.
eLife 6. pii: e26280

TRPM3
Oberwinkler J
In: Choi S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. doi: 10.1007/978-1-4614-6438-9_101920-1. Review


2016

Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122
Leitner MG, Michel N, Behrendt M, Dierich M, Dembla S, Wilke BU, Konrad M, Lindner M, Oberwinkler J, Oliver D
Br J Pharmacol 173(16):2555-2569

Phosphoinositide regulation of TRPM channels - TRPM3 joins the club!
Tóth BI, Oberwinkler J, Voets T
Channels (Austin) 10(2):83-85. Review


2015

Regulation of the transient receptor potential channel TRPM3 by phosphoinositides
Tóth BI, Konrad M, Ghosh D, Mohr F, Halaszovich CR, Leitner MG, Vriens J, Oberwinkler J, Voets T
J Gen Physiol 146(1):51-63

Properties and functions of TRPM1 channels in the dendritic tips of retinal ON-bipolar cells
Schneider FM, Mohr F, Behrendt M, Oberwinkler J
Eur J Cell Biol 94(7-9):420-427. Review

Permeation, regulation and control of expression of TRP channels by trace metal ions
Bouron A, Kiselyov K, Oberwinkler J
Pflügers Arch 467(6):1143-1164. Review


2014

Structural requirements of steroidal agonists of transient receptor potential melastatin 3 (TRPM3) cation channels
Drews A, Mohr F, Rizun O, Wagner TF, Dembla S, Rudolph S, Lambert S, Konrad M, Philipp SE, Behrendt M, Marchais-Oberwinkler S, Covey DF, Oberwinkler J
Br J Pharmacol
171(4):1019-1032

Contribution of calcium-conducting channels to the transport of zinc ions
Bouron A, Oberwinkler J
Pflügers Arch 466(3):381-387. Review

 

2013

Flavanones that selectively inhibit TRPM3 attenuate thermal nociception in vivo
Straub I, Krügel U, Mohr F, Teichert J, Rizun O, Konrad M, Oberwinkler J, Schaefer M
Mol Pharmacol
84(5):736-750

Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3
Straub I, Mohr F, Stab J, Konrad M, Philipp S, Oberwinkler J, Schaefer M
Br J Pharmacol
168(8):1835-1850


2012

Alternative splicing of a protein domain indispensable for function of transient receptor potential melastatin 3 (TRPM3) ion channels
Frühwald J, Camacho Londoño J, Dembla S, Mannebach S, Lis A, Drews A, Wissenbach U, Oberwinkler J, Philipp SE
J Biol Chem 287(44):36663-36672

Bile acids acutely stimulate insulin secretion of mouse β-cells via farnesoid X receptor activation and K(ATP) channel inhibition
Düfer M, Hörth K, Wagner R, Schittenhelm B, Prowald S, Wagner TF, Oberwinkler J, Lukowski R, Gonzalez FJ, Krippeit-Drews P, Drews G
Diabetes 61(6):1479-1489

 

2011

TRPM3 is a nociceptor channel involved in the detection of noxious heat
Vriens J, Owsianik G, Hofmann T, Philipp SE, Stab J, Chen X, Benoit M, Xue F, Janssens A, Kerselaers S, Oberwinkler J, Vennekens R, Gudermann T, Nilius B, Voets T
Neuron 70(3):482-494

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions
Lambert S, Drews A, Rizun O, Wagner TF, Lis A, Mannebach S, Plant S, Portz M, Meissner M, Philipp SE, Oberwinkler J
J Biol Chem 286(14):12221-12233

 

2010

TRPM channels mediate zinc homeostasis and cellular growth during Drosophila larval development
Georgiev P, Okkenhaug H, Drews A, Wright D, Lambert S, Flick M, Carta V, Martel C, Oberwinkler J, Raghu P
Cell Metab 12(4):386-397

TRPM3 channels provide a regulated influx pathway for zinc in pancreatic beta cells
Wagner TF, Drews A, Loch S, Mohr F, Philipp SE, Lambert S, Oberwinkler J
Pflügers Arch 460(4):755-765

 

2008

Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic beta cells
Wagner TF, Loch S, Lambert S, Straub I, Mannebach S, Mathar I, Düfer M, Lis A, Flockerzi V, Philipp SE, Oberwinkler J
Nat Cell Biol 10(12):1421-1430

 

2007

TRPM3, a biophysical enigma?
Oberwinkler J
Biochem Soc Trans 35(Pt 1):89-90. Review [Abstract]

TRPM3
Oberwinkler J, Phillipp SE
Handb Exp Pharmacol 179:253-267. Review [Abstract]

 

2005

Mechanisms of light adaptation in Drosophila photoreceptors
Gu Y, Oberwinkler J, Postma M, Hardie RC
Curr Biol 15(13):1228-1234

Characterization of a proton-activated, outwardly rectifying anion channel
Lambert S, Oberwinkler J
J Physiol 567(Pt 1):191-213

Alternative splicing switches the divalent cation selectivity of TRPM3 channels
Oberwinkler J, Lis A, Giehl KM, Flockerzi V, Philipp SE
J Biol Chem 280(23):22540-22548

Light activation, adaptation, and cell survival functions of the Na+/Ca2+ exchanger CalX
Wang T, Xu H, Oberwinkler J, Gu Y, Hardie RC, Montell C
Neuron 45(3):367-378

 

2002

Calcium homeostasis in fly photoreceptor cells
Oberwinkler J
Adv Exp Med Biol 514:539-583. Review

 

2000

Calcium imaging demonstrates colocalization of calcium influx and extrusion in fly photoreceptors
Oberwinkler J, Stavenga DG
Proc Natl Acad Sci U S A 97(15):8578-8583

Calcium transients in the rhabdomeres of dark- and light-adapted fly photoreceptor cells
Oberwinkler J, Stavenga DG
J Neurosci 20(5):1701-1709

 

1999

The colourful world of the mantis shrimp
Marshall J, Oberwinkler J
Nature 401(6756):873-874

Does Ca2+ reach millimolar concentrations after single photon absorption in Drosophila photoreceptor microvilli?
Postma M, Oberwinkler J, Stavenga DG
Biophys J 77(4):1811-1823

 

1998

Light dependence of calcium and membrane potential measured in blowfly photoreceptors in vivo
Oberwinkler J, Stavenga DG
J Gen Physiol 112(2):113-124

 

Zuletzt aktualisiert: 02.02.2021 · oberwink

 
 
 
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