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Publikationen AG Garn

  • Co-culture of human AT2 cells with fibroblasts reveals a MUC5B phenotype: insights from an organoid model.
    Yao, Y., Ritzmann, F., Miethe, S., Kattler-Lackes, K., Colakoglu, B., Herr, C., Kamyschnikow, A., Brand, M., Garn, H., Yildiz, D., Langer, F., Bals, R., & Beisswenger, C. (2024). 
    Molecular medicine (Cambridge, Mass.), 30(1), 227. https://doi.org/10.1186/s10020-024-00990-w
  • Arachidonic Acid Directly Activates the Human DP2 Receptor.
    Kurz, M., Ulrich, M., Kirchhofer, S. B., Bittner, A., Daude, M., Diederich, W. E., Pauck, K., Garn, H., & Bünemann, M. (2024). 
    Molecular pharmacology, 106(5), 216–224. https://doi.org/10.1124/molpharm.124.000884
  • BAG6 restricts pancreatic cancer progression by suppressing the release of IL33-presenting extracellular vesicles and the activation of mast cells.
    Alashkar Alhamwe B, Ponath V, Alhamdan F, Dörsam B, Landwehr C, Linder M, Pauck K, Miethe S, Garn H, Finkernagel F, Brichkina A, Lauth M, Tiwari DK, Buchholz M, Bachurski D, Elmshäuser S, Nist A, Stiewe T, Pogge von Strandmann L, Szymański W, Beutgen V, Graumann J, Teply-Szymanski J, Keber C, Denkert C, Jacob R, Preußer C, Pogge von Strandmann E. (2024).
    Cellular & molecular immunology, 21(8), 918–931. https://doi.org/10.1038/s41423-024-01195-1
  • Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells.
    Neuhaus, F., Lieber, S., Shinkevich, V., Steitz, A. M., Raifer, H., Roth, K., Finkernagel, F., Worzfeld, T., Burchert, A., Keber, C., Nist, A., Stiewe, T., Reinartz, S., Beutgen, V. M., Graumann, J., Pauck, K., Garn, H., Gaida, M., Müller, R., & Huber, M. (2024). 
    Clinical and translational medicine, 14(4), e1604. https://doi.org/10.1002/ctm2.1604
  • Recent Developments in the Role of Histone Acetylation in Asthma.
    Potaczek, D. P., Bazan-Socha, S., Wypasek, E., Wygrecka, M., & Garn, H. (2024). 
    International archives of allergy and immunology, 185(7), 641–651. https://doi.org/10.1159/000536460
  • Reply to correspondence "Extracellular vesicle microRNA signatures as novel biomarkers in obese asthmatics".
    Alhamdan, F., Potaczek, D. P., Greulich, T., Tost, J., & Garn, H. (2024). 
    Allergy, 79(5), 1401–1402. https://doi.org/10.1111/all.16042
  • Mutual Regulation of Transcriptomes between Murine Pneumocytes and Fibroblasts Mediates Alveolar Regeneration in Air-Liquid Interface Cultures.
    Yao, Y., Miethe, S., Kattler, K., Colakoglu, B., Walter, J., Schneider-Daum, N., Herr, C., Garn, H., Ritzmann, F., Bals, R., & Beisswenger, C. (2024).
    American journal of respiratory cell and molecular biology, 70(3), 203–214. https://doi.org/10.1165/rcmb.2023-0078OC
  • Epithelial-immune cell interactions in allergic diseases.
    Albrecht, M., Garn, H., & Buhl, T. (2024).
    European journal of immunology, 54(1), e2249982. https://doi.org/10.1002/eji.202249982
  • Type 2 T-Cell Responses against Distinct Epitopes of the Desmoglein 3 Ectodomain in Pemphigus Vulgaris.
    Didona D, Scarsella L, Hudemann C, Volkmann K, Zimmer CL, Beckert B, Tikkanen R, Korff V, Kühn K, Wienzek-Lischka S, Bein G, Di Zenzo G, Böhme J, Cunha T, Solimani F, Pieper J, Juratli HA, Göbel M, Schmidt T, Borradori L, Yazdi AS, Sitaru C, Garn H, Eming R, Fleischer S, Hertl M. (2024). 
    The Journal of investigative dermatology, 144(2), 263–272.e8. https://doi.org/10.1016/j.jid.2023.07.025

  • Human Lung Organoids-A Novel Experimental and Precision Medicine Approach.
    Kühl, L., Graichen, P., von Daacke, N., Mende, A., Wygrecka, M., Potaczek, D. P., Miethe, S., & Garn, H. (2023).
    Cells, 12(16), 2067. https://doi.org/10.3390/cells12162067
  • Identification of extracellular vesicle microRNA signatures specifically linked to inflammatory and metabolic mechanisms in obesity-associated low type-2 asthma.
    Alhamdan, F., Greulich, T., Daviaud, C., Marsh, L. M., Pedersen, F., Thölken, C., Pfefferle, P. I., Bahmer, T., Potaczek, D. P., Tost, J., & Garn, H. (2023).
    Allergy, 78(11), 2944–2958. https://doi.org/10.1111/all.15824
  • The emerging role of extracellular vesicles as communicators between adipose tissue and pathologic lungs with a special focus on asthma.
    Miethe, S., Potaczek, D. P., Bazan-Socha, S., Bachl, M., Schaefer, L., Wygrecka, M., & Garn, H. (2023). 
    American journal of physiology. Cell physiology, 324(5), C1119–C1125. https://doi.org/10.1152/ajpcell.00057.2023
  • Intranasal administration of Acinetobacter lwoffii in a murine model of asthma induces IL-6-mediated protection associated with cecal microbiota changes.
    Alashkar Alhamwe, B., Gao, Z., Alhamdan, F., Harb, H., Pichene, M., Garnier, A., El Andari, J., Kaufmann, A., Graumann, P. L., Kesper, D., Daviaud, C., Garn, H., Tost, J., Potaczek, D. P., Blaser, M. J., & Renz, H. (2023).
    Allergy, 78(5), 1245–1257. https://doi.org/10.1111/all.15606

  • Timing of Blood Sample Processing Affects the Transcriptomic and Epigenomic Profiles in CD4+ T-cells of Atopic Subjects.
    Alhamdan, F., Laubhahn, K., Happle, C., Habener, A., Jirmo, A. C., Thölken, C., Conca, R., Chung, H. R., Hansen, G., Potaczek, D. P., Schaub, B., Grychtol, R., & Garn, H. (2022). 
    Cells, 11(19), 2958. https://doi.org/10.3390/cells11192958
  • Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19. 
    Aznaourova M, Schmerer N, Janga H, Zhang Z, Pauck K, Bushe J, Volkers SM, Wendisch D, Georg P, Ntini E, Aillaud M, Gündisch M, Mack E, Skevaki C, Keller C, Bauer C, Bertrams W, Marsico A, Nist A, Stiewe T, Gruber AD, Ruppert C, Li Y, Garn H, Sander LE, Schmeck B, Schulte LN. (2022).
    Proceedings of the National Academy of Sciences of the United States of America, 119(36), e2120680119. https://doi.org/10.1073/pnas.2120680119
  • Local and Systemic Production of Pro-Inflammatory Eicosanoids Is Inversely Related to Sensitization to Aeroallergens in Patients with Aspirin-Exacerbated Respiratory Disease.
    Potaczek, D. P., Trąd, G., Sanak, M., Garn, H., & Mastalerz, L. (2022).  
     
    Journal of personalized medicine, 12(3), 447. https://doi.org/10.3390/jpm12030447
  • Side-Directed Release of Differential Extracellular Vesicle-associated microRNA Profiles from Bronchial Epithelial Cells of Healthy and Asthmatic Subjects.
    Schindler, V. E. M., Alhamdan, F., Preußer, C., Hintz, L., Alashkar Alhamwe, B., Nist, A., Stiewe, T., Pogge von Strandmann, E., Potaczek, D. P., Thölken, C., & Garn, H. (2022).
    Biomedicines, 10(3), 622. https://doi.org/10.3390/biomedicines10030622

  • Differential Regulation of Interferon Signaling Pathways in CD4+ T Cells of the Low Type-2 Obesity-Associated Asthma Phenotype.
    Alhamdan F, Marsh LM, Pedersen F, Alhamwe BA, Thölken C, Pfefferle PI, Bahmer T, Greulich T, Potaczek DP, Garn H. (2021).
    International journal of molecular sciences, 22(18), 10144. https://doi.org/10.3390/ijms221810144
  • Editorial: The Immunological Implications of the Hygiene Hypothesis.
    Pfefferle, P. I., Postigo, I., & Garn, H. (2021).
    Frontiers in immunology, 12, 732127. https://doi.org/10.3389/fimmu.2021.732127
  • Mitogen-activated protein kinase signaling in childhood asthma development and environment-mediated protection.
    Theodorou, J., Nowak, E., Böck, A., Salvermoser, M., Beerweiler, C., Zeber, K., Kulig, P., Tsang, M. S., Wong, C. K., Wong, G., Roponen, M., Kumbrink, J., Alhamdan, F., Michel, F., Garn, H., Tosevski, V., & Schaub, B. (2021). 
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 10.1111/pai.13657.  https://doi.org/10.1111/pai.13657
  • Epigenetic Mechanisms in Allergy Development and Prevention.
    Potaczek, D. P., Alashkar Alhamwe, B., Miethe, S., & Garn, H. (2021). 
    Handbook of experimental pharmacology, 10.1007/164_2021_475. https://doi.org/10.1007/164_2021_475
  • Extracellular Vesicles and Asthma-More Than Just a Co-Existence.
    Alashkar Alhamwe, B., Potaczek, D. P., Miethe, S., Alhamdan, F., Hintz, L., Magomedov, A., & Garn, H. (2021).
    International journal of molecular sciences, 22(9), 4984. https://doi.org/10.3390/ijms22094984
  • Constitutive immune activity promotes JNK- and FoxO-dependent remodeling of Drosophila airways.
    Wagner, C., Uliczka, K., Bossen, J., Niu, X., Fink, C., Thiedmann, M., Knop, M., Vock, C., Abdelsadik, A., Zissler, U. M., Isermann, K., Garn, H., Pieper, M., Wegmann, M., Koczulla, A. R., Vogelmeier, C. F., Schmidt-Weber, C. B., Fehrenbach, H., König, P., Silverman, N., … Roeder, T. (2021). 
    Cell reports, 35(1), 108956. https://doi.org/10.1016/j.celrep.2021.108956
  •  The Hygiene Hypothesis and New Perspectives-Current Challenges Meeting an Old Postulate.
    Garn, H., Potaczek, D. P., & Pfefferle, P. I. (2021).
    Frontiers in immunology, 12, 637087. https://doi.org/10.3389/fimmu.2021.637087
  • The Hygiene Hypothesis - Learning From but Not Living in the Past.
    Pfefferle, P. I., Keber, C. U., Cohen, R. M., & Garn, H. (2021). 
    Frontiers in immunology, 12, 635935. https://doi.org/10.3389/fimmu.2021.635935
  • Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function.
    Lacorcia, M., Bhattacharjee, S., Laubhahn, K., Alhamdan, F., Ram, M., Muschaweckh, A., Potaczek, D. P., Kosinska, A., Garn, H., Protzer, U., Renz, H., & Prazeres da Costa, C. (2021). 
    The Journal of allergy and clinical immunology, 148(3), 843–857.e6. https://doi.org/10.1016/j.jaci.2021.02.031
  • Perinatal and Early-Life Nutrition, Epigenetics, and Allergy.
    Acevedo, N., Alashkar Alhamwe, B., Caraballo, L., Ding, M., Ferrante, A., Garn, H., Garssen, J., Hii, C. S., Irvine, J., Llinás-Caballero, K., López, J. F., Miethe, S., Perveen, K., Pogge von Strandmann, E., Sokolowska, M., Potaczek, D. P., & van Esch, B. (2021). 
    Nutrients, 13(3), 724. https://doi.org/10.3390/nu13030724
  • Allergen-specific immunotherapy induces the suppressive secretoglobin 1A1 in cells of the lower airways.
    Zissler, U. M., Jakwerth, C. A., Guerth, F., Lewitan, L., Rothkirch, S., Davidovic, M., Ulrich, M., Oelsner, M., Garn, H., Schmidt-Weber, C. B., & Chaker, A. M. (2021). 
    Allergy, 76(8), 2461–2474. https://doi.org/10.1111/all.14756

  • Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice.
    Hanschmann, E. M., Berndt, C., Hecker, C., Garn, H., Bertrams, W., Lillig, C. H., & Hudemann, C. (2020). 
    Frontiers in immunology, 11, 561724. https://doi.org/10.3389/fimmu.2020.561724
  • Noninvasive and minimally invasive techniques for the diagnosis and management of allergic diseases.
    Baumann, R., Untersmayr, E., Zissler, U. M., Eyerich, S., Adcock, I. M., Brockow, K., Biedermann, T., Ollert, M., Chaker, A. M., Pfaar, O., Garn, H., Thwaites, R. S., Togias, A., Kowalski, M. L., Hansel, T. T., Jakwerth, C. A., & Schmidt-Weber, C. B. (2021). 
    Allergy, 76(4), 1010–1023. https://doi.org/10.1111/all.14645
  • The role of epigenetics in allergy and asthma development.
    Alashkar Alhamwe, B., Alhamdan, F., Ruhl, A., Potaczek, D. P., & Renz, H. (2020). 
    Current opinion in allergy and clinical immunology, 20(1), 48–55. https://doi.org/10.1097/ACI.0000000000000598
  • Obesity and asthma.
    Miethe, S., Karsonova, A., Karaulov, A., & Renz, H. (2020). 
    The Journal of allergy and clinical immunology, 146(4), 685–693. https://doi.org/10.1016/j.jaci.2020.08.011
  • Decreased Histone Acetylation Levels at Th1 and Regulatory Loci after Induction of Food Allergy.
    Alashkar Alhamwe, B., Meulenbroek, L., Veening-Griffioen, D. H., Wehkamp, T., Alhamdan, F., Miethe, S., Harb, H., Hogenkamp, A., Knippels, L., Pogge von Strandmann, E., Renz, H., Garssen, J., van Esch, B., Garn, H., Potaczek, D. P., & Tiemessen, M. M. (2020). 
    Nutrients, 12(10), 3193. https://doi.org/10.3390/nu12103193
  • Epigenetic Regulation of Airway Epithelium Immune Functions in Asthma.
    Alashkar Alhamwe, B., Miethe, S., Pogge von Strandmann, E., Potaczek, D. P., & Garn, H. (2020). 
    Frontiers in immunology, 11, 1747. https://doi.org/10.3389/fimmu.2020.01747
  • T cell requirement and phenotype stability of house dust mite-induced neutrophil airway inflammation in mice.
    Hagner, S., Keller, M., Raifer, H., Tan, H. T., Akdis, C. A., Buch, T., Sokolowska, M., & Garn, H. (2020). 
    Allergy, 75(11), 2970–2973. https://doi.org/10.1111/all.14424
  • Role of airway epithelial cells in the development of different asthma phenotypes.
    Potaczek, D. P., Miethe, S., Schindler, V., Alhamdan, F., & Garn, H. (2020). 
    Cellular signalling, 69, 109523. https://doi.org/10.1016/j.cellsig.2019.109523
  • EAACI position paper on diet diversity in pregnancy, infancy and childhood: Novel concepts and implications for studies in allergy and asthma.
    Venter, C., Greenhawt, M., Meyer, R. W., Agostoni, C., Reese, I., du Toit, G., Feeney, M., Maslin, K., Nwaru, B. I., Roduit, C., Untersmayr, E., Vlieg-Boerstra, B., Pali-Schöll, I., Roberts, G. C., Smith, P., Akdis, C. A., Agache, I., Ben-Adallah, M., Bischoff, S., Frei, R., … O'Mahony, L. (2020).
    Allergy, 75(3), 497–523. https://doi.org/10.1111/all.14051

  • Raw Cow's Milk Reduces Allergic Symptoms in a Murine Model for Food Allergy-A Potential Role For Epigenetic Modifications.
    Abbring, S., Wolf, J., Ayechu-Muruzabal, V., Diks, M., Alhamwe, B. A., Alhamdan, F., Harb, H., Renz, H., Garn, H., Garssen, J., Potaczek, D. P., & van Esch, B. (2019). 
    Nutrients, 11(8), 1721. https://doi.org/10.3390/nu11081721
  • EAACI position paper: Influence of dietary fatty acids on asthma, food allergy, and atopic dermatitis.
    Venter, C., Meyer, R. W., Nwaru, B. I., Roduit, C., Untersmayr, E., Adel-Patient, K., Agache, I., Agostoni, C., Akdis, C. A., Bischoff, S. C., du Toit, G., Feeney, M., Frei, R., Garn, H., Greenhawt, M., Hoffmann-Sommergruber, K., Lunjani, N., Maslin, K., Mills, C., Muraro, A., … O'Mahony, L. (2019). 
    Allergy, 74(8), 1429–1444. https://doi.org/10.1111/all.13764
  • Flow Cytometry-Based Cell Type-Specific Assessment of Target Regulation by Pulmonary siRNA Delivery.
    Merkel, O. M., Marsh, L. M., Garn, H., & Kissel, T. (2019).
    Methods in molecular biology (Clifton, N.J.), 1943, 365–375. https://doi.org/10.1007/978-1-4939-9092-4_24
  • Hepatic gene expression in mouse models of non-alcoholic fatty liver disease after acute exercise.
    Piguet, A. C., Guarino, M., Potaczek, D. P., Garn, H., & Dufour, J. F. (2019). 
    Hepatology research : the official journal of the Japan Society of Hepatology, 49(6), 637–652. https://doi.org/10.1111/hepr.13323
  • Neuroimaging markers of global cognition in early Alzheimer's disease: A magnetic resonance imaging-electroencephalography study.
    Waser, M., Benke, T., Dal-Bianco, P., Garn, H., Mosbacher, J. A., Ransmayr, G., Schmidt, R., Seiler, S., Sorensen, H., & Jennum, P. J. (2019). 
    Brain and behavior, 9(1), e01197. https://doi.org/10.1002/brb3.1197
  • Associations of event-related brain potentials and Alzheimer's disease severity: A longitudinal study.
    Fruehwirt, W., Dorffner, G., Roberts, S., Gerstgrasser, M., Grossegger, D., Schmidt, R., Dal-Bianco, P., Ransmayr, G., Garn, H., Waser, M., & Benke, T. (2019). 
    Progress in neuro-psychopharmacology & biological psychiatry, 92, 31–38. https://doi.org/10.1016/j.pnpbp.2018.12.013
  • Tight junction, mucin, and inflammasome-related molecules are differentially expressed in eosinophilic, mixed, and neutrophilic experimental asthma in mice.
    Tan, H. T., Hagner, S., Ruchti, F., Radzikowska, U., Tan, G., Altunbulakli, C., Eljaszewicz, A., Moniuszko, M., Akdis, M., Akdis, C. A., Garn, H., & Sokolowska, M. (2019). 
    Allergy, 74(2), 294–307. https://doi.org/10.1111/all.13619
  • Neurobiology of the major psychoses: a translational perspective on brain structure and function-the FOR2107 consortium.
    Kircher, T., Wöhr, M., Nenadic, I., Schwarting, R., Schratt, G., Alferink, J., Culmsee, C., Garn, H., Hahn, T., Müller-Myhsok, B., Dempfle, A., Hahmann, M., Jansen, A., Pfefferle, P., Renz, H., Rietschel, M., Witt, S. H., Nöthen, M., Krug, A., & Dannlowski, U. (2019). 
    European archives of psychiatry and clinical neuroscience, 269(8), 949–962. https://doi.org/10.1007/s00406-018-0943-x
  • Development and characterization of DNAzyme candidates demonstrating significant efficiency against human rhinoviruses.
    Potaczek, D. P., Unger, S. D., Zhang, N., Taka, S., Michel, S., Akdağ, N., Lan, F., Helfer, M., Hudemann, C., Eickmann, M., Skevaki, C., Megremis, S., Sadewasser, A., Alashkar Alhamwe, B., Alhamdan, F., Akdis, M., Edwards, M. R., Johnston, S. L., Akdis, C. A., Becker, S., … Renz, H. (2019). 
    The Journal of allergy and clinical immunology, 143(4), 1403–1415. https://doi.org/10.1016/j.jaci.2018.07.026

  • Histone modifications and their role in epigenetics of atopy and allergic diseases.
    Alaskhar Alhamwe, B., Khalaila, R., Wolf, J., von Bülow, V., Harb, H., Alhamdan, F., Hii, C. S., Prescott, S. L., Ferrante, A., Renz, H., Garn, H., & Potaczek, D. P. (2018).
    Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 14, 39. https://doi.org/10.1186/s13223-018-0259-4
  • Effects of obesity on asthma: immunometabolic links.
    Miethe, S., Guarino, M., Alhamdan, F., Simon, H. U., Renz, H., Dufour, J. F., Potaczek, D. P., & Garn, H. (2018). 
    Polish archives of internal medicine, 128(7-8), 469–477. https://doi.org/10.20452/pamw.4304