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Publikationen

  • Inhalt ausklappen Inhalt einklappen 20122012

    • Jockel, S., G. Nees, R. Sommer, Y. Zhao, D. Cherkasov, H. Hori, G. Ehm, M. Schnare, M. Nain, A. Kaufmann, and S. Bauer. 2012. The 2'-O-methylation status of a single guanosine controls transfer RNA-mediated Toll-like receptor 7 activation or inhibition. J Exp Med 209:235-241.
    • Obermann, H. L., and S. Bauer. 2012. Toll-like receptor 9, what o'clock is it? Immunity 36:159-161.

    • Koppe, U., K. Hogner, J. M. Doehn, H. C. Muller, M. Witzenrath, B. Gutbier, S. Bauer, T. Pribyl, S. Hammerschmidt, J. Lohmeyer, N. Suttorp, S. Herold, and B. Opitz. 2012. Streptococcus pneumoniae stimulates a STING- and IFN regulatory factor 3-dependent type I IFN production in macrophages, which regulates RANTES production in macrophages, cocultured alveolar epithelial cells, and mouse lungs. J Immunol 188:811-817.
    • Dicke, T., I. Pali-Scholl, A. Kaufmann, S. Bauer, H. Renz, and H. Garn. 2012. Absence of unspecific innate immune cell activation by GATA-3-specific DNAzymes. Nucleic Acid Ther 22:117-126.
  • Inhalt ausklappen Inhalt einklappen 20112011

    • Prinz, N., N. Clemens, D. Strand, I. Putz, M. Lorenz, A. Daiber, P. Stein, A. Degreif, M. Radsak, H. Schild, S. Bauer, P. von Landenberg, and K. J. Lackner. 2011. Antiphospholipid antibodies induce translocation of TLR7 and TLR8 to the endosome in human monocytes and plasmacytoid dendritic cells. Blood 118:2322-2332.

    • Lippmann, J., H. C. Muller, J. Naujoks, C. Tabeling, S. Shin, M. Witzenrath, K. Hellwig, C. J. Kirschning, G. A. Taylor, W. Barchet, S. Bauer, N. Suttorp, C. R. Roy, and B. Opitz. 2011. Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice. Cell Microbiol 13:1668-1682.

    • Klaffenbach, D., D. Friedrich, R. Strick, P. L. Strissel, M. W. Beckmann, W. Rascher, A. Gessner, J. Dotsch, U. Meissner, and M. Schnare. 2011. Contribution of different placental cells to the expression and stimulation of antimicrobial proteins (AMPs). Placenta 32:830-837.
    • Jantsch, J., M. Wiese, J. Schodel, K. Castiglione, J. Glasner, S. Kolbe, D. Mole, U. Schleicher, K. U. Eckardt, M. Hensel, R. Lang, C. Bogdan, M. Schnare, and C. Willam. 2011. Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1alpha (HIF1A) and result in differential HIF1A-dependent gene expression. J Leukoc Biol 90:551-562.

    • Groseth, A., T. Hoenen, M. Weber, S. Wolff, A. Herwig, A. Kaufmann, and S. Becker. 2011. Tacaribe virus but not junin virus infection induces cytokine release from primary human monocytes and macrophages. PLoS Negl Trop Dis 5:e1137.

    • Deshmukh, S. D., B. Kremer, M. Freudenberg, S. Bauer, D. T. Golenbock, and P. Henneke. 2011. Macrophages recognize streptococci through bacterial single-stranded RNA. EMBO Rep 12:71-76.
    • Brenner, S., D. Drewel, T. Steinbart, F. Weisel, E. Hartel, S. Potzsch, H. Welzel, A. Brandl, P. Yu, G. C. Mudde, A. Schweizer, L. Nitschke, and T. H. Winkler. 2011. A hypomorphic IgH-chain allele affects development of B-cell subsets and favours receptor editing. Embo J 30:2705-2718.

    • Abe, K., H. Fuchs, A. Boersma, W. Hans, P. Yu, S. Kalaydjiev, M. Klaften, T. Adler, J. Calzada-Wack, I. Mossbrugger, B. Rathkolb, J. Rozman, C. Prehn, M. Maraslioglu, Y. Kametani, S. Shimada, J. Adamski, D. H. Busch, I. Esposito, M. Klingenspor, E. Wolf, W. Wurst, V. Gailus-Durner, M. Katan, S. Marschall, D. Soewarto, S. Wagner, and M. H. de Angelis. 2011. A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cgamma2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis Rheum 63:1301-1311.
  • Inhalt ausklappen Inhalt einklappen 20102010

    • Lafferty, E. I., S. T. Qureshi, and M. Schnare. 2010. The role of toll-like receptors in acute and chronic lung inflammation. J Inflamm (Lond) 7:57.

    • Hamm, S., E. Latz, D. Hangel, T. Muller, P. Yu, D. Golenbock, T. Sparwasser, H. Wagner, and S. Bauer. 2010. Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist. Immunobiology 215:559-569.

    • Elvers, M., R. Pozgaj, I. Pleines, F. May, M. J. Kuijpers, J. M. Heemskerk, P. Yu, and B. Nieswandt. 2010. Platelet hyperreactivity and a prothrombotic phenotype in mice with a gain-of-function mutation in phospholipase Cgamma2. J Thromb Haemost 8:1353-1363.

    • Doring, Y., J. Hurst, M. Lorenz, N. Prinz, N. Clemens, M. D. Drechsler, S. Bauer, J. Chapman, Y. Shoenfeld, M. Blank, K. J. Lackner, and P. von Landenberg. 2010. Human antiphospholipid antibodies induce TNFalpha in monocytes via Toll-like receptor 8. Immunobiology 215:230-241.

    • Bauer, S., B. Bathke, H. Lauterbach, J. Patzold, R. Kassub, C. A. Luber, B. Schlatter, S. Hamm, P. Chaplin, M. Suter, and H. Hochrein. 2010. A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC? Proc Natl Acad Sci U S A 107:E139; author reply E140.
  • Inhalt ausklappen Inhalt einklappen 20092009

    • Tluk, S., M. Jurk, A. Forsbach, R. Weeratna, U. Samulowitz, A. M. Krieg, S. Bauer, and J. Vollmer. 2009. Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses. Int Immunol 21:607-619.

    • Shibamiya, A., K. Hersemeyer, T. Schmidt Woll, D. Sedding, J. M. Daniel, S. Bauer, T. Koyama, K. T. Preissner, and S. M. Kanse. 2009. A key role for Toll-like receptor-3 in disrupting the hemostasis balance on endothelial cells. Blood 113:714-722.

    • Rad, R., W. Ballhorn, P. Voland, K. Eisenacher, J. Mages, L. Rad, R. Ferstl, R. Lang, H. Wagner, R. M. Schmid, S. Bauer, C. Prinz, C. J. Kirschning, and A. Krug. 2009. Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori. Gastroenterology 136:2247-2257.

    • Kiemer, A. K., R. H. Senaratne, J. Hoppstadter, B. Diesel, L. W. Riley, K. Tabeta, S. Bauer, B. Beutler, and B. L. Zuraw. 2009. Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. J Innate Immun 1:29-45.

    • Hurst, J., N. Prinz, M. Lorenz, S. Bauer, J. Chapman, K. J. Lackner, and P. von Landenberg. 2009. TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1beta and caspase-1 in monocytes and dendritic cells. Immunobiology 214:683-691.

    • Hecker, A., A. Kaufmann, M. Hecker, W. Padberg, and V. Grau. 2009. Expression of interleukin-21, interleukin-21 receptor alpha and related type I cytokines by intravascular graft leukocytes during acute renal allograft rejection. Immunobiology 214:41-49.

    • Everett, K. L., T. D. Bunney, Y. Yoon, F. Rodrigues-Lima, R. Harris, P. C. Driscoll, K. Abe, H. Fuchs, M. H. de Angelis, P. Yu, W. Cho, and M. Katan. 2009. Characterization of phospholipase C gamma enzymes with gain-of-function mutations. J Biol Chem 284:23083-23093.

    • Bauer, S., T. Muller, and S. Hamm. 2009. Pattern recognition by Toll-like receptors. Adv Exp Med Biol 653:15-34.
  • Inhalt ausklappen Inhalt einklappen 20082008

    • Yu, P., P. Musette, and S. L. Peng. 2008. Toll-like receptor 9 in murine lupus: more friend than foe! Immunobiology 213:151-157.

    • Muller, T., S. Hamm, and S. Bauer. 2008. TLR9-mediated recognition of DNA. Handb Exp Pharmacol:51-70.

    • Kalali, B. N., G. Kollisch, J. Mages, T. Muller, S. Bauer, H. Wagner, J. Ring, R. Lang, M. Mempel, and M. Ollert. 2008. Double-stranded RNA induces an antiviral defense status in epidermal keratinocytes through TLR3-, PKR-, and MDA5/RIG-I-mediated differential signaling. J Immunol 181:2694-2704.

    • Holler, J., A. Zakrzewicz, A. Kaufmann, J. Wilhelm, G. Fuchs-Moll, H. Dietrich, W. Padberg, J. Kuncova, W. Kummer, and V. Grau. 2008. Neuropeptide Y is expressed by rat mononuclear blood leukocytes and strongly down-regulated during inflammation. J Immunol 181:6906-6912.

    • Guggemoos, S., D. Hangel, S. Hamm, A. Heit, S. Bauer, and H. Adler. 2008. TLR9 contributes to antiviral immunity during gammaherpesvirus infection. J Immunol 180:438-443.

    • Bauer, S., S. Pigisch, D. Hangel, A. Kaufmann, and S. Hamm. 2008. Recognition of nucleic acid and nucleic acid analogs by Toll-like receptors 7, 8 and 9. Immunobiology 213:315-328.
  • Inhalt ausklappen Inhalt einklappen 20072007

    • von Landenberg, P., and S. Bauer. 2007. Nucleic acid recognizing Toll-like receptors and autoimmunity. Curr Opin Immunol 19:606-610.

    • Sel, S., M. Wegmann, S. Sel, S. Bauer, H. Garn, G. Alber, and H. Renz. 2007. Immunomodulatory effects of viral TLR ligands on experimental asthma depend on the additive effects of IL-12 and IL-10. J Immunol 178:7805-7813.

    • Schwarz, H., K. Schneider, A. Ohnemus, M. Lavric, S. Kothlow, S. Bauer, B. Kaspers, and P. Staeheli. 2007. Chicken toll-like receptor 3 recognizes its cognate ligand when ectopically expressed in human cells. J Interferon Cytokine Res 27:97-101.

    • Schmidt, A., J. Sucke, G. Fuchs-Moll, P. Freitag, M. Hirschburger, A. Kaufmann, H. Garn, W. Padberg, and V. Grau. 2007. Macrophages in experimental rat lung isografts and allografts: infiltration and proliferation in situ. J Leukoc Biol 81:186-194.

    • Rad, R., L. Brenner, A. Krug, P. Voland, J. Mages, R. Lang, S. Schwendy, W. Reindl, A. Dossumbekova, W. Ballhorn, H. Wagner, R. M. Schmid, S. Bauer, and C. Prinz. 2007. Toll-like receptor-dependent activation of antigen-presenting cells affects adaptive immunity to Helicobacter pylori. Gastroenterology 133:150-163 e153.

    • Porter, M., M. Karp, S. Killedar, S. M. Bauer, J. Guo, D. Williams, P. Breysse, S. N. Georas, and M. A. Williams. 2007. Diesel-enriched particulate matter functionally activates human dendritic cells. Am J Respir Cell Mol Biol 37:706-719.

    • Hamm, S., A. Heit, M. Koffler, K. M. Huster, S. Akira, D. H. Busch, H. Wagner, and S. Bauer. 2007. Immunostimulatory RNA is a potent inducer of antigen-specific cytotoxic and humoral immune response in vivo. Int Immunol 19:297-304.

    • Forsbach, A., J. G. Nemorin, K. Volp, U. Samulowitz, C. Montino, C. Muller, S. Tluk, S. Hamm, S. Bauer, G. B. Lipford, and J. Vollmer. 2007. Characterization of conserved viral leader RNA sequences that stimulate innate immunity through TLRs. Oligonucleotides 17:405-417.

    • Brustle, A., S. Heink, M. Huber, C. Rosenplanter, C. Stadelmann, P. Yu, E. Arpaia, T. W. Mak, T. Kamradt, and M. Lohoff. 2007. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat Immunol 8:958-966.

    • Blocher, S., S. Wilker, J. Sucke, U. Pfeil, H. Dietrich, R. Weimer, K. Steger, A. Kaufmann, M. Hirschburger, C. Plotz, W. Padberg, and V. Grau. 2007. Acute rejection of experimental lung allografts: characterization of intravascular mononuclear leukocytes. Clin Immunol 124:98-108.

    • Bauer, S., D. Hangel, and P. Yu. 2007. Immunobiology of toll-like receptors in allergic disease. Immunobiology 212:521-533.
  • Inhalt ausklappen Inhalt einklappen 20062006

    • Yu, P., U. Wellmann, S. Kunder, L. Quintanilla-Martinez, L. Jennen, N. Dear, K. Amann, S. Bauer, T. H. Winkler, and H. Wagner. 2006. Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE. Int Immunol 18:1211-1219.

    • Yasuda, K., M. Rutz, B. Schlatter, J. Metzger, P. B. Luppa, F. Schmitz, T. Haas, A. Heit, S. Bauer, and H. Wagner. 2006. CpG motif-independent activation of TLR9 upon endosomal translocation of "natural" phosphodiester DNA. Eur J Immunol 36:431-436.

    • Wagner, H., and S. Bauer. 2006. All is not Toll: new pathways in DNA recognition. J Exp Med 203:265-268.

    • von Meyenn, F., M. Schaefer, H. Weighardt, S. Bauer, C. J. Kirschning, H. Wagner, and T. Sparwasser. 2006. Toll-like receptor 9 contributes to recognition of Mycobacterium bovis Bacillus Calmette-Guerin by Flt3-ligand generated dendritic cells. Immunobiology 211:557-565.

    • Savarese, E., O. W. Chae, S. Trowitzsch, G. Weber, B. Kastner, S. Akira, H. Wagner, R. M. Schmid, S. Bauer, and A. Krug. 2006. U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. Blood 107:3229-3234.

    • Rad, R., L. Brenner, S. Bauer, S. Schwendy, L. Layland, C. P. da Costa, W. Reindl, A. Dossumbekova, M. Friedrich, D. Saur, H. Wagner, R. M. Schmid, and C. Prinz. 2006. CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo. Gastroenterology 131:525-537.

    • Loseke, S., E. Grage-Griebenow, H. Heine, A. Wagner, S. Akira, S. Bauer, and A. Bufe. 2006. In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells. Scand J Immunol 63:264-274.

    • Bauer, S. 2006. Toll-erating self DNA. Nat Immunol 7:13-15.

    • Baiyee, E. E., S. Flohe, S. Lendemans, S. Bauer, N. Mueller, E. Kreuzfelder, and H. Grosse-Wilde. 2006. Expression and function of Toll-like receptor 9 in severely injured patients prone to sepsis. Clin Exp Immunol 145:456-462.