Hauptinhalt
Publikationen der Mitglieder der AG Bewegungsstörungen und Neuromodulation
Hier finden sich alle wissenschaftlichen Veröffentlichungen der Mitglieder der Arbeitsgruppe aufgelistet nach Jahren.
2024
Calvano, A., Kleinholdermann, U., Heun, A. S., Bopp, M. H., Nimsky, C., Timmermann, L., & Pedrosa, D. J. (2024). Structural connectivity of low-frequency subthalamic stimulation for improving stride length in Parkinson’s disease. NeuroImage: Clinical, 103591.
Garon, M., Weck, C., Rosqvist, K., Odin, P., Schrag, A., Krikmann, Ü., ... & Paal, P. (2024). A systematic practice review: Providing palliative care for people with Parkinson’s disease and their caregivers. Palliative Medicine, 38(1), 57-68.
Greten, S., Wegner, F., Jensen, I., Krey, L., Rogozinski, S., Fehring, M., ... & Klietz, M. (2024). The comorbidity and co-medication profile of patients with progressive supranuclear palsy. Journal of Neurology, 271(2), 782-793.
Laugisch, O., Ruppert-Jungck, M. C., Auschill, T. M., Eick, S., Sculean, A., Heumann, C., ... & Arweiler, N. B. (2024). Glucose-6-Phosphatase-Dehydrogenase activity as modulative association between Parkinson’s disease and periodontitis. Frontiers in cellular and infection microbiology, 14, 1298546.
Oltra, J., Segura, B., Strafella, A. P., van Eimeren, T., Ibarretxe-Bilbao, N., Diez-Cirarda, M., ... & Junque, C. (2024). A multi-site study on sex differences in cortical thickness in non-demented Parkinson’s disease. npj Parkinson's Disease, 10(1), 69.
Pedrosa, A. J., Feldmann, S., Klippel, J., Volberg, C., Weck, C., Stefan, L., & Pedrosa, D. J. (2024). Factors Associated with Preferred Place of Care and Death in Patients with Parkinson’s Disease: A Cross-Sectional Study. Journal of Parkinson's Disease, (Preprint), 1-11.
Salehi, N., Nahrgang, S., Petershagen, W., Dembek, T. A., Pedrosa, D., Timmermann, L., ... & Oehrn, C. R. (2024). Theta frequency deep brain stimulation in the subthalamic nucleus improves working memory in Parkinson’s disease. Brain, awad433.
2023
Atkinson, A. C., Duarte, B. P., Pedrosa, D. J., & van Munster, M. (2023). Randomizing a clinical trial in neuro-degenerative disease. Contemporary Clinical Trials Communications, 33, 101140. https://doi.org/10.1016/j.conctc.2023.101140
Buchwitz, T. M., Ruppert-Junck, M. C., Greuel, A., Maier, F., Thieken, F., Jakobs, V., & Eggers, C. (2023). Exploring impaired self-awareness of motor symptoms in Parkinson's disease: Resting-state fMRI correlates and the connection to mindfulness. PloS One, 18(2), e0279722. DOI: https://doi.org/10.1371/journal.pone.0279722
Calvano, A., Beccaria, L., Bopp, M. H., Gjorgjevski, M., Nimsky, C., & Pedrosa, D. J. (2023). Case report: Unilateral GPi DBS in secondary myoclonus-dystonia syndrome after acute disseminated encephalomyelitis. Frontiers in Neurology, 14, 1238743.
Kleinholdermann, U., Bacara, B., Timmermann, L., & Pedrosa, D. J. (2023). Prediction of Movement Ratings and Deep Brain Stimulation Parameters in Idiopathic Parkinson’s Disease. Neuromodulation: Technology at the Neural Interface, 26(2), 356-363. https://doi.org/10.1016/j.neurom.2022.09.010
Mügge, F., Kleinholdermann, U., Heun, A., Ollenschläger, M., Hannink, J., & Pedrosa, D. J. (2023). Subthalamic 85 Hz deep brain stimulation improves walking pace and stride length in Parkinson’s disease patients. Neurological Research and Practice, 5(1), 33. https://doi.org/10.1186/s42466-023-00263-7
Pedrosa, A. J., Waldthaler, J., Mügge, F., Timmermann, L., & Pedrosa, D. J. (2023). Non‐lesional treatments for tremor in Parkinson's disease: A systematic review and meta‐analysis. European Journal of Neurology, 30(8), 2544-2556. https://doi.org/10.1111/ene.15823
Ruppert-Junck, M. C., Torfah, L., Greuel, A., Maier, F., Hammes, V., Timmermann, L., Eggers, C., & Pedrosa, D. (2023). Why the clock ticks differently in Parkinson's disease: Insights from motor imagery and resting-state functional magnetic resonance imaging. Heliyon, 9(4), e14741. DOI: https://doi.org/10.1016/j.heliyon.2023.e14741
Usnich, T., Olmedillas, M., Schell, N., Paul, J. J., Curado, F., Skobalj, S., ... & Brüggemann, N. (2023). Frequency of non-motor symptoms in Parkinson's disease patients carrying the E326K and T369M GBA risk variants. Parkinsonism & Related Disorders, 107. DOI: https://doi.org/10.1016/j.parkreldis.2022.105248
van Munster, M., Printz, M. R., Crighton, E., Mestre, T. A., Pedrosa, D. J., & iCARE-PD Consortium. (2023). Impact of the COVID-19 pandemic on perceived access and quality of care in German people with parkinsonism. Frontiers in Public Health, 11, 1091737.
Waldthaler, J., Sperlich, A., König, A., Stüssel, C., Bremmer, F., Timmermann, L., & Pedrosa, D. (2023). High (130 Hz)-and mid (60 Hz)-frequency deep brain stimulation in the subthalamic nucleus differentially modulate response inhibition: A preliminary combined EEG and eye tracking study. NeuroImage: Clinical, 103314. DOI: https://doi.org/10.1016/j.nicl.2023.103314
Waldthaler, J., Sperlich, A., Stüssel, C., Steidel, K., Timmermann, L., & Pedrosa, D. J. (2023). Stimulation of non-motor subthalamic nucleus impairs selective response inhibition via prefrontal connectivity. Brain Communications, 5(2), fcad121. https://doi.org/10.1093/braincomms/fcad121
2022
Grüter, T., Möllers, F. E., Tietz, A., Dargvainiene, J., Melzer, N., Heidbreder, A., ... & Ayzenberg, I. (2022). Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease. Brain. DOI: https://doi.org/10.1093/brain/awac090
Kleinholdermann U, Bacara B, Timmermann L, Pedrosa DJ. Prediction of Movement Ratings and Deep Brain Stimulation Parameters in Idiopathic Parkinson's Disease. Neuromodulation. 2022 Nov 14:S1094-7159(22)01289-2. DOI: https://doi.org/10.1016/j.neurom.2022.09.010
Monte-Rubio, G., Segura, B., Strafella, A., van Eimeren, T., Ibarretxe-Bilbao, N., Díez-Cirarda, M., Eggers, C., Lucas-Jiménez, O., Ojeda, N., Peña, J., Ruppert, M.C., Sala-Llonch, R., Theis,H., Uribe-Codesal, C., Junque, C. Parameters from site classification to harmonize MRI clinical studies: Application to a multi-center Parkinson’s Disease dataset (2022). Human Brain Mapping, 43(10), 3130–3142. DOI: https://doi.org/10.1002/hbm.25838
Muente, C., Folkerts, A. K., Kalbe, E., Thieken, F., Assmann, L. E., Widritzki, M., ... & Wilhelm, M. (2022). Supporting Relatives Prior to Caregiver Burden—Preventive E-Mental Health Short Intervention for Family Members of Individuals with Parkinsonism in an Early Phase of the Disease: Protocol for a Feasibility Study. Brain Sciences, 12(4), 442. DOI: https://doi.org/10.3390/brainsci12040442
Pedrosa, D. J., Gandor, F., Jost, W. H., Arlt, C., Onuk, K., & Timmermann, L. (2022). Characterization of advanced Parkinson’s disease in Germany: results of the non-interventional OBSERVE-PD study. Neurological research and practice, 4(1), 1-10. DOI: https://doi.org/10.1186/s42466-022-00176-x
Steidel, K., Ruppert, M. C., Greuel, A., Tahmasian, M., Maier, F., Hammes, J., . . . Eggers, C. (2022). Longitudinal trimodal imaging of midbrain-associated network degeneration in Parkinson's disease. NPJ Parkinson's Disease, 8(1), 79. DOI: https://doi.org/10.1038/s41531-022-00341-8
Stührenberg, M., Berghäuser, C. S., van Munster, M., Pedrosa Carrasco, A. J., Pedrosa, D. J., & iCARE-Pd Consortium. (2022). Measuring quality of life in Parkinson’s disease—A call to rethink conceptualizations and assessments. Journal of Personalized Medicine, 12(5), 804. https://doi.org/10.3390/jpm12050804
Stümpel J, van Munster M, Grosjean S, Pedrosa DJ, Mestre TA, On Behalf Of The iCare-Pd Consortium. Coping Styles in Patients with Parkinson's Disease: Consideration in the Co-Designing of Integrated Care Concepts. J Pers Med. 2022 Jun 1;12(6):921. DOI: https://doi.org/10.3390/jpm12060921
Tönges, L., Buhmann, C., Klebe, S., Klucken, J., Kwon, E. H., Müller, T., ... & Lingor, P. (2022). Blood-based biomarker in Parkinson’s disease: potential for future applications in clinical research and practice. Journal of Neural Transmission, 1-17. DOI: https://doi.org/10.1007/s00702-022-02498-1
Usnich T, Olmedillas M, Schell N, Paul JJ, Curado F, Skobalj S, Csoti I, Ertan S, Gruber D, Zittel S, Sammler E, Isaacson SH, Kühn AA, Pedrosa DJ, Reetz K, Kasten M, Rolfs A, Bauer P, Skrahina V, Klein C, Brüggemann N; LIPAD Study Group. Frequency of non-motor symptoms in Parkinson's disease patients carrying the E326K and T369M GBA risk variants. Parkinsonism Relat Disord. 2022 Dec 17;107:105248. DOI: https://doi.org/10.1016/j.parkreldis.2022.105248.
van Munster M, Stümpel J, Thieken F, Ratajczak F, Rascol O, Fabbri M, Clemens T, Czabanowska K, Mestre TA, Pedrosa DJ; iCARE-PD consortium. The Role of Parkinson Nurses for Personalizing Care in Parkinson's Disease: A Systematic Review and Meta-Analysis. J Parkinsons Dis. 2022;12(6):1807-1831. https://doi.org/10.3233/JPD-223215
Waldthaler J, Sperlich A, König A, Stüssel C, Bremmer F, Timmermann L, Pedrosa DJ. High- and Low-Frequency Deep Brain Stimulation in the Subthalamic Nucleus differentially modulate Response Inhibition and Action Selection in Parkinson’s Disease. BioRxiv [preprint]. DOI: https://doi.org/10.1101/2022.05.13.491771
2021
Carrasco, A. J. P., Mügge, F., & Pedrosa, D. J. (2021). Non-lesional treatment options for tremor in idiopathic Parkinson syndrome: a protocol for a systematic literature review. BMJ Open, 11(8), e048367. DOI: 10.1136/bmjopen-2020-048367
Kleinholdermann, U., Wullstein, M., & Pedrosa, DJ. (2021). Prediction of motor Unified Parkinson's Disease Rating Scale scores in patients with Parkinson’s disease using surface electromyography. Clinical Neurophysiology. DOI: 10.1016/j.clinph.2021.01.031
Rommal, A., an Vo, Schindlbeck, K. A., Greuel, A., Ruppert, M. C., Eggers, C., & Eidelberg, D. (2021). Parkinson's disease-related pattern (PDRP) identified using resting-state functional MRI: Validation study. Neuroimage: Reports, 1(3), 100026. DOI: 10.1016/j.ynirp.2021.100026
Ruppert, M. C., Greuel, A., Freigang, J., Tahmasian, M., Maier, F., Hammes, J., van Eimeren, T., Timmermann, L., Tittgemeyer, M., Drzezga, A., & Eggers, C. (2021). The default mode network and cognition in Parkinson's disease: A multimodal resting-state network approach. Human Brain Mapping, 42(8), 2623–2641. https://doi.org/10.1002/hbm.25393
Steidel K, Krause K, Menzler K, Strzelczyk A, Immisch I, Fuest S, Gorny I, Mross P, Hakel L, Schmidt L, Timmermann L, Rosenow F, Bauer S, Knake S (2021) Transcutaneous auricular vagus nerve stimulation influences gastric motility : A randomized, double-blind trial in healthy individuals, Brain Stimul 2021 DOI: 10.1016/j.brs.2021.06.006
Steidel, K.; Ruppert, M. C.; Palaghia, I.; Greuel, A.; Tahmasian, M.; Maier, F. Hammes, J.; van Eimeren, T.; Timmermann, L; Tittgemeyer, M.; Drzezga, A.; Pedrosa, D.; Eggers, C. al. (2021): Dopaminergic pathways and resting-state functional connectivity in Parkinson’s disease with freezing of gait. In: NeuroImage: Clinical 32, S. 102899. DOI: 10.1016/j.nicl.2021.102899.
Usnich, T., Vollstedt, E. J., Schell, N., Skrahina, V., Bogdanovic, X., Gaber, H., ... & LIPAD Study Group. (2021). LIPAD (LRRK2/Luebeck International Parkinson's Disease) Study Protocol: Deep Phenotyping of an International Genetic Cohort. Frontiers in Neurology, 1360. DOI: https://doi.org/10.3389/fneur.2021.710572
van Munster, M., Stümpel, J., Thieken, F., Pedrosa, D., Antonini, A., Côté, D., ... & Mestre, T. A. (2021). Moving towards Integrated and Personalized Care in Parkinson’s Disease: A Framework Proposal for Training Parkinson Nurses. Journal of Personalized Medicine, 11(7), 623. DOI: 10.3390/jpm11070623
Waldthaler, J., Bopp, M., Kühn, N., Bacara, B., Keuler, M., Gjorgjevski, M., ... & Pedrosa, D. J. (2021). Imaging-based programming of subthalamic nucleus deep brain stimulation in Parkinson's disease. Brain Stimulation. DOI: 10.1016/j.brs.2021.07.064
2020
Greuel, A., Trezzi, J.-P., Glaab, E., Ruppert, M. C., Maier, F., Jäger, C., Hodak, Z., Lohmann, K., Ma, Y., Eidelberg, D., Timmermann, L., Hiller, K., Tittgemeyer, M., Drzezga, A., Diederich, N., & Eggers, C. (2020). GBA variants in Parkinson's disease: Clinical, metabolomic, and multimodal neuroimaging phenotypes. Movement Disorders : Official Journal of the Movement Disorder Society, 35(12), 2201–2210. DOI: 10.1002/mds.28225
Loehrer PA, Timmermann L, Pehl A, Bien CI, Pfestroff A, Pedrosa DJ. Rhombencephalitis associated with isolated Zic4-antibodies in Paraneoplastic cerebellar degeneration: a case report. BMC Neurol. 2020 May 25;20(1):208. doi: 10.1186/s12883-020-01788-z.
Pedrosa Carrasco, A. J., Volberg, C., Pedrosa, D. J., & Berthold, D. (2020). Patient Safety in Palliative and End-of-Life Care: A Text Mining Approach and Systematic Review of Definitions. American Journal of Hospice and Palliative Medicine®, DOI: 10.1177/1049909120971825
Ruppert, M. C., Greuel, A., Tahmasian, M., Schwartz, F., Stürmer, S., Maier, F., Hammes, J., Tittgemeyer, M., Timmermann, L., van Eimeren, T., Drzezga, A., & Eggers, C. (2020). Network degeneration in Parkinson's disease: Multimodal imaging of nigro-striato-cortical dysfunction. Brain : A Journal of Neurology, 143(3), 944–959. DOI: 10.1093/brain/awaa019
Tabatabaei, Seyed & Pedrosa, David & Eggers, Carsten & Wullstein, Max & Kleinholdermann, Urs & Fischer, Patrick & Sohrabi, Keywan. (2020). Machine Learning Techniques for Parkinson’s Disease Detection using Wearables during a Timed-up-and-Go-Test. Current Directions in Biomedical Engineering. 6. 376-379. DOI: 10.1515/cdbme-2020-3097/html
van Munster M., Tönges L., Loewenbrück K.F., Warnecke T., Eggers C. (2020). Building a Parkinson-Network–Experiences from Germany. Journal of Clinical Medicine, 9(9):2743. DOI: 10.3390/jcm9092743
2019
Kleinholdermann, U., Melsbach, J., Pedrosa, D.J. Remote-Messung bei idiopathischem Parkinson-Syndrom: Entwicklungen in Diagnose, Monitoring und Therapie [Remote assessment of idiopathic Parkinson's disease : Developments in diagnostics, monitoring and treatment]. Nervenarzt. 2019 Dec;90(12):1232-1238. German. DOI: 10.1007/s00115-019-00818-7
Tan, H., Debarros, J., He, S., Pogosyan, A., Aziz, T.Z., Huang, Y., Wang, S., Timmermann, L., Visser-Vandewalle, V., Pedrosa, D.J., Green, A.L., Brown, P. Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor. Brain Stimul. 2019 Jul-Aug;12(4):858-867. DOI: 10.1016/j.brs.2019.02.011
2018
Kleinholdermann, U., Melsbach, J., Pedrosa, D.J. Remote-Messung bei idiopathischem Parkinson-Syndrom: Entwicklungen in Diagnose, Monitoring und Therapie [Remote assessment of idiopathic Parkinson's disease : Developments in diagnostics, monitoring and treatment]. Nervenarzt. 2019 Dec;90(12):1232-1238. German. DOI: 10.1007/s00115-019-00818-7
Pedrosa, D.J., Brown, P., Cagnan, H., Visser-Vandewalle, V., Wirths, J., Timmermann, L., Brittain, J.S. A functional micro-electrode mapping of ventral thalamus in essential tremor. Brain. 2018 Sep 1;141(9):2644-2654. DOI: 10.1093/brain/awy192
Herz, D.M., Little, S., Pedrosa, D.J., Tinkhauser, G., Cheeran, B., Foltynie, T., Bogacz, R., Brown, P. Mechanisms Underlying Decision-Making as Revealed by Deep-Brain Stimulation in Patients with Parkinson's Disease. Curr Biol. 2018 Apr 23;28(8):1169-1178.e6. DOI: 10.1016/j.cub.2018.02.057.
2017
di Biase, L., Brittain, J.S., Shah, S.A, Pedrosa, D.J., Cagnan, H., Mathy, A., Chen, C.C., Martín-Rodríguez J.F., Mir, P., Timmermann, L,. Schwingenschuh, P., Bhatia, K., Di Lazzaro, V., Brown, P. Tremor stability index: a new tool for differential diagnosis in tremor syndromes. Brain. 2017 Jul 1;140(7):1977-1986. DOI: 10.1093/brain/awx104.
Pedrosa, D.J., Timmermann, L. Deep brain stimulation in Tourette's syndrome: new insights. Lancet Neurol. 2017 Aug;16(8):575-576. DOI: 10.1016/S1474-4422(17)30206-5.
Pedrosa, D.J., Nelles, C., Maier, F., Eggers, C., Burghaus, L., Fink, G.R., Wittmann, M., Timmermann, L. Time reproduction deficits in essential tremor patients. Mov Disord. 2016 Aug;31(8):1234-40. DOI: 10.1002/mds.26630.
Pedrosa, D.J., Nelles, C., Brown, P., Volz, L.J., Pelzer, E.A., Tittgemeyer, M., Brittain, J.S., Timmermann, L. The differentiated networks related to essential tremor onset and its amplitude modulation after alcohol intake. Exp Neurol. 2017 Nov;297:50-61. DOI: 10.1016/j.expneurol.2017.07.013.
Pelzer, E.A., Nelles, C., Pedrosa, D.J., Eggers, C., Burghaus, L., Melzer, C., Tittgemeyer, M., Timmermann, L. Structural differences in impaired verbal fluency in essential tremor patients compared to healthy controls. Brain Behav. 2017 May 15;7(7):e00722. DOI: 10.1002/brb3.722.
2016
Pedrosa, D.J., Nelles, C., Maier, F., Eggers, C., Burghaus, L., Fink, G.R., Wittmann, M., Timmermann, L. Variance of essential tremor patients' time reproduction deficits. Mov Disord. 2016 Sep;31(9):1428-9. doi: 10.1002/mds.26736
2014
Pedrosa, D.J., Auth, M., Pauls, K.A., Runge, M., Maarouf, M., Fink, G.R., Timmermann, L. Verbal fluency in essential tremor patients: the effects of deep brain stimulation. Brain Stimul. 2014 May-Jun;7(3):359-64. DOI: 10.1016/j.brs.2014.02.012.
Eggers, C., Schwartz, F., Pedrosa, D.J., Kracht, L., Timmermann, L. Parkinson's disease subtypes show a specific link between dopaminergic and glucose metabolism in the striatum. PLoS One. 2014 May 21;9(5):e96629. DOI: 10.1371/journal.pone.0096629.
Pedrosa, D.J., Quatuor, E.L., Reck, C., Pauls, K.A., Huber, C.A., Visser-Vandewalle, V., Timmermann, L. Thalamomuscular coherence in essential tremor: hen or egg in the emergence of tremor? J Neurosci. 2014 Oct 22;34(43):14475-83. DOI: 10.1523/JNEUROSCI.0087-14.2014.
Maier, F., Merkl, J., Ellereit, A.L., Lewis, C.J., Eggers, C., Pedrosa, D.J., Kalbe, E., Kuhn, J., Meyer, T.D., Zurowski, M., Timmermann L. Hypomania and mania related to dopamine replacement therapy in Parkinson's disease. Parkinsonism Relat Disord. 2014 Apr;20(4):421-7. DOI: 10.1016/j.parkreldis.2014.01.001.
2013
Pedrosa, D.J., Timmermann, L. Review: management of Parkinson's disease. Neuropsychiatr Dis Treat. 2013;9:321-40. doi: 10.2147/NDT.S32302.
Pedrosa, D.J., Auth, M., Eggers, C., Timmermann, L. Effects of low-frequency thalamic deep brain stimulation in essential tremor patients. Exp Neurol. 2013 Oct;248:205-12. DOI: 10.1016/j.expneurol.2013.06.009.
2012
Eggers, C. and Pedrosa, D.J., Kahraman, D., Maier, F., Lewis, C.J., Fink, G.R., Schmidt, M., Timmermann, L. Parkinson subtypes progress differently in clinical course and imaging pattern. PLoS One. 2012;7(10):e46813. DOI: 10.1371/journal.pone.00468
Kahraman, D., Eggers, C., Holstein, A., Schneider, C., Pedrosa, D.J., Dietlein, M., Kobe, C., Timmermann, L., Schmidt, M. 123I-FP-CIT SPECT imaging of the dopaminergic state. Visual assessment of dopaminergic degeneration patterns reflects quantitative 2D operator-dependent and 3D operator-independent techniques. Nuklearmedizin. 2012;51(6):244-51. DOI: 10.3413/Nukmed-0449-11-12.
Pedrosa D.J., Geyer, C., Klosterkötter, J., Fink, G.R., Burghaus, L. Anti-NMDA-Rezeptor-Enzephalitis: Ein neurologisch-psychiatrischer Notfall [Anti-NMDA receptor encephalitis: a neurological and psychiatric emergency]. Fortschr Neurol Psychiatr. 2012 Jan;80(1):29-35. German. DOI: 10.1055/s-0031-1281961.
Pedrosa, D.J., Reck, C., Florin, E., Pauls, K.A., Maarouf, M., Wojtecki, L., Dafsari, H.S., Sturm, V., Schnitzler, A., Fink, G.R., Timmermann, L. Essential tremor and tremor in Parkinson's disease are associated with distinct 'tremor clusters' in the ventral thalamus. Exp Neurol. 2012 Oct;237(2):435-43. DOI: 10.1016/j.expneurol.2012.07.002.