Hauptinhalt

Beste Publikationen Grundlagenforschung 2018

 

Institut für Molekularbiologie und Tumorforschung (IMT)

Bouchard C, Sahu P, Meixner M, Nötzold RR, Rust MB, Kremmer E, Feederle R, Hart-Smith G, Finkernagel F, Bartkuhn M, Savai Pullamsetti S, Nist A, Stiewe T, Philipsen S, Bauer UM (2018) Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes. Cell Rep 24(12):3339-3352

Feld C, Sahu P, Frech M, Finkernagel F, Nist A, Stiewe T, Bauer UM, Neubauer A (2018) Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1. Nucleic Acids Res 46(7):3412-3428

Kovac K, Sauer A, Macinkovic I, Awe S, Finkernagel F, Hoffmeister H, Fuchs A, Müller R, Rathke C, Längst G, Brehm A (2018) Tumour-associated missense mutations in the dMi-2 ATPase alters nucleosome remodelling properties in a mutation-specific manner. Nat Commun 9(1):2112

 

Institut für Physiologische Chemie

Antoniou A, Khudayberdiev S, Idziak A, Bicker S, Jacob R, Schratt G (2018) The dynamic recruitment of TRBP to neuronal membranes mediates dendritogenesis during development. EMBO Rep 19(3) e44853

Lackinger M, Sungur AÖ, Daswani R, Soutschek M, Bicker S, Stemmler L, Wüst T, Fiore R, Dieterich C, Schwarting RK, Wöhr M, Schratt G (2018) A placental mammal-specific microRNA cluster acts as a natural brake for sociability in mice. EMBO Rep 20(2) e46429

 

Institut für Lungenforschung

Schulte LN, Heinrich B, Janga H, Schmeck BT, Vázquez O (2018) A Far-Red Fluorescent DNA Binder for Interaction Studies of Live Multidrug-Resistant Pathogens and Host Cells. Angew Chem Int Ed 57(36):11564-11568

  

Institut für Klinische Zytobiologie und Zytpathologie

Bänfer S, Schneider D, Dewes J, Strauss MT, Freibert SA, Heimerl T, Maier UG, Elsässer HP, Jungmann R, Jacob R (2018) Molecular mechanism to recruit galectin-3 into multivesicular bodies for polarized exosomal secretion. Proc Natl Acad Sci 115(19): 4396-4405

Stehling O, Jeoung JH, Freibert SA, Paul VD, Bänfer S, Niggemeyer B, Rösser R, Dobbek H, Lill R (2018) Function and crystal structure of the dimeric P-loop ATPase CFD1 coordinating an exposed [4Fe-4S] cluster for transfer to apoproteins. Proc Natl Acad Sci 115(39): 9085-9094

  

Institut für Virologie

Huttner A, Agnandji ST, Combescure C, Fernandes JF, Bache EB, Kabwende L, Ndungu FM, Brosnahan J, Monath TP, Lemaitre B, Grillet S, Botto M, Engler O, Portmann J, Siegrist D, Bejon P, Silvera P, Kremsner P, Siegrist CA, VEBCON: … Becker S, Kähling V, VSV-EBOVAC, Consortia V-E (2018) Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study. Lancet Infectious Diseases 18 (7): 738-748

Kruse T, Biedenkopf N, Hertz EPT, Dietzel E, Stalmann G, Lopez-Mendez B, Davey NE, Nilsson J, Becker, S (2018) The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30. Mol Cell 69, 136-145.e6

Takamatsu Y, Kolesnikova, L, Becker S (2018) Ebola virus proteins NP, VP35, and VP24 are essential and sufficient to mediate nucleocapsid transport. Proc Nat Acad Sci USA 115 (5): 1075-1080

 

Exerimentelle Tumorforschung

Sud A, Thomsen H, Orlando G, Försti A, Law PJ, Broderick P, Cooke R, Hariri F, Pastinen T, Easton DF, Pharoah PDP, Dunning AM, Peto J, Canzian F, Eeles R, Kote-Jarai ZS, Muir K, Pashayan N, Campa D, PRACTICAL Consortium, Hoffmann P, Nöthen MM, Jöckel K-H, von Strandmann EP, Swerdlow AJ, Engert A, Orr N, Hemminki K, Houlston RS (2018) Genome-wide association  study implicates immune dysfunction in the development of Hodgkin lymphoma. Blood 132(19): 2040–2052

  

Auswahlkriterien

Originalarbeit, Erst- oder Letztautor und Journal Impact Faktor > 7,5 oder
Originalarbeit, Mitautorenschaft und Journal Impact Faktor > 14