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Publications 2010-2011

149) Schwenkert, S.*, Netz, D.J.A.*, Frazzon, J., Pierik, A.J., Bill, E., Gross, J., Lill, R., & Meurer, J. (2010). Chloroplast HCF101 is a scaffold protein for [4Fe-4S] cluster assembly. Biochem. J. 425, 207-214.    * Joint first authors

150) Ihrig, J., Hausmann, A., Hain, A., Richter, N., Hamza, I., Lill, R., & Mühlenhoff, U. (2010). Iron regulation through the back door: Iron-dependent metabolite levels contribute to transcriptional adaptation to iron deprivation in Saccharomyces cerevisiae. Eukaryot. Cell 9, 460-471.

151) Sheftel, A., Stehling, O., & Lill R. (2010). Iron-sulfur proteins in health and disease. Trends Endocrinol. Metab. 21, 302-314.

152) Albrecht, A.G., Netz, D.J.A., Miethke, M., Pierik, A.J., Burghaus, O., Peuckert, F., Lill, R.*, & Marahiel, M.A.* (2010). SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis. J. Bacteriol. 192, 1643-1651.   * Joint corresponding authors

153) Pierrel, F., Hamelin, O., Douky, T., Kieffer-Jaquinod, S., Mühlenhoff, U., Ozeir, M., Lill, R., and Fontecave, M. (2010). Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis. Chem. Biol. 17, 449-459.  Commentary by Rötig, A. (2010) Chem. Biol. 17, 415-416.

154) Sheftel, A.D., Stehling, O., Pierik, A.J., Elsässer, H.P., Mühlenhoff, U., Webert, H., Hobler, A., Hannemann, F., Bernhardt, R., & Lill, R. (2010). Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct functions in steroidogenesis, heme and Fe/S cluster biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 107, 11775-11780.

155) Mühlenhoff, U., Molik, S., Godoy, J.R., Uzarska, M.A., Richter, N., Seubert, A., Zhang, Y.,  Stubbe, J., Pierrel, F., Herrero, E., Lillig, C.H. & Lill, R. (2010). Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metab. 12 , 373-385.

156) Netz, D.J.A., Stümpfig, M., Doré, C., Mühlenhoff, U., Pierik, A.J. & Lill, R. (2010). Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis. Nature Chem. Biol. 6, 758-765.  Commentary by DosSantos and Dean (2010) Nature Chem. Biol. 6, 700-701.

157) Hoffmann, B., Uzarska, M.A., Berndt, C., Godoy, J.R., Haunhorst, P., Lillig, C.H., Lill, R., & Mühlenhoff, U. (2011). The multidomain thioredoxin-monothiol glutaredoxins represent a distinct functional group. Antioxid. Redox Signal. 15, 19-30.

158) Castells-Roca, L., Mühlenhoff, U., Lill, R., Herrero, E., & Belli, G. (2011). The oxidative stress response in yeast cells involves changes in the stability of Aft1 regulon mRNAs. Mol. Microbiol. 81, 232-248.

159) Ozeir, M., Mühlenhoff, U., Webert, H., Lill, R., Fontecave, M., & Pierrel, F. (2011). Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency. Chem. Biol. 18, 1134-42.  Commentary by Clarke, C.F. (2011) Chem. Biol. 18, 1069-1070.

160) Mühlenhoff, U., Richter, N., Pines, O., Pierik, A.J., & Lill, R. (2011). Specialized function of yeast Isa1 and Isa2 in the maturation of mitochondrial [4Fe-4S] proteins. J. Biol. Chem.  286, 41205-41216.

161) Navarro-Sastre, A.*, Tort, F.*, Stehling, O*., Uzarska, M.A.*, Arranz, J.A., del Toro, M., Labayru, M.T., Landa, J., Font, A., Garcia-Villoria, J., Merinero, B., Ugarte, M., Gutierrez-Solana, L.G., Campistol, J., Garcia-Cazorla, A., Vaquerizo, J., Riudor, E., Briones, P., Elpeleg, O., Ribes, A.#, & Lill, R.# (2011). A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins. Am. J. Hum. Genet. 89, 656-667.  * Joint first authors; # joint corresponding authors.