11.01.2024 Joint paper by Martin Thanbichler and Gert Bange published

A newly discovered molecular switch mechanism plays a central role in the infection process in bacterial dysentery.

@Wellcome Collection/David Goulding, Wellcome Trust Sanger Institute.
New Insights into Shigellosis

Bacteria of the genus Shigella, closely related to the well-known E. coli, are the second most common cause of fatal bacterial diarrheal diseases, with over 200,000 victims worldwide every year. There are repeated outbreaks of strains that are resistant to common antibiotics. In order to better control Shigella and other pathogenic bacteria, researchers around the world are looking for new therapeutic targets. Researchers in Marburg have now provided insights into bacterial gene regulation, which at the same time contribute to a better understanding of the infectious capacity. Click here for more information about the research of Martin’s team and the paper published in Nature Communications, involving Gert.