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Publikationen 2022-2024

2024

Slusny B, Zimmer V, Nasiri E, Lutz V, Huber M, Buchholz M, Gress TM, Roth K, Bauer
Dec 2024
Optimized Spheroid Model of Pancreatic Cancer Demonstrates Influence of Macrophage-T Cell Interaction for Intratumoral T Cell Motility

Soll D, Chu CF, Sun S, Lutz V, Arunkumar M, Gachechiladze M, Schäuble S, Alissa-Alkhalaf M, Nguyen T, Khalil MA, Garcia-Ribelles I, Mueller M, Buder K, Michalke B, Panagiotou G, Ziegler-Martin K, Benz P, Schatzlmaier P, Hiller K, Stockinger H, Luu M, Schober K, Moosmann C, Schamel WW, Huber M,Zielinski CE.
Oct 2024
Sodium chloride in the tumor microenvironment enhances T cell metabolic fitness and cytotoxicity.

Krause FF, Mangold KI, Ruppert AL, Leister H, Hellhund-Zingel A, Lopez Krol A, Pesek J, Watzer B, Winterberg S, Raifer H, Binder K, Kinscherf R, Walker A, Nockher WA, Taudte RV, Bertrams W, Schmeck B, Kühl AA, Siegmund B, Romero R, Luu M, Göttig S, Bekeredjian-Ding I, Steinhoff U, Schütz B, Visekruna A.
Oct 2024
Clostridium sporogenes-derived metabolites protect mice against colonic inflammation

Simon C, Brunke ID, Stielow B, Forné I, Steitz AM, Geller M, Rohner I, Weber LM, Fischer S, Jeude LM, Huber T, Nist A, Stiewe T, Huber M, Buchholz M, Liefke R.
Aug 2024
SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma

Karimova AF, Ketkar A, Suezov R, Khalitova AR, Gomzikova M, Mukhamedshina Y, Lauth M, Huber M, Simon HU, Brichkina A.
Jul 2024
In vitro functional assays to assess the reciprocal interplay between tumor cells and macrophages

Fischer S, Weber LM, Stielow B, Frech M, Simon C, Geller M, Könnecke J, Finkernagel F, Forné I, Nist A, Bauer UM, Stiewe T, Neubauer A, Liefke R.
Jul 2024
IRF2BP2 counteracts the ATF7/JDP2 AP-1 heterodimer to prevent inflammatory overactivation in acute myeloid leukemia (AML) cells

Böttrich T, Bauer P, Gröβer V, Huber M, Raifer H, Frech T, Nolte S, Dombrowski T, Cemic F, Sommer N, Ringseis R, Eder K, Krüger K, Weyh C.
May 2024
Subpopulations of regulatory T cells are associated with subclinical atherosclerotic plaques, levels of LDL, and cardiorespiratory fitness in the elderly

Neuhaus F, Lieber S, Shinkevich V, Steitz AM, Raifer H, Roth K, Finkernagel F, Worzfeld T, Burchert A, Keber C, Nist A, Stiewe T, Reinartz S, Beutgen VM, Graumann J, Pauck K, Garn H, Gaida M, Müller R, Huber M.
Apr. 2024
Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells

Zhao K, Braun M, Meyer L, Otte K, Raifer H, Helmprobst F, Möschl V, Pagenstecher A, Urban H, Ronellenfitsch MW, Steinbach JP, Pesek J, Watzer B, Nockher WA, Taudte RV, Neubauer A, Nimsky C, Bartsch JW, Rusch T.
Apr. 2024
A Novel Approach for Glioblastoma Treatment by Combining Apoptosis Inducers (TMZ, MTX, and Cytarabine) with E.V.A. (Eltanexor, Venetoclax, and A1210477) Inhibiting XPO1, Bcl-2, and Mcl-1

Hoffmann J, Rheude A, Neubauer A, Brendel C, Thrun MC.
Development of an explainable AI system using routine clinical parameters for rapid differentiation of inflammatory conditions

Balz K, Grange M, Pegel U, Karamya ZA, Mello M, Zhou X, Berger T, Bloch K, Dunham D, Chinthrajah S, Nadeau K, Luche H, Skevaki C
Jan.2024
A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen-specific T cells.

2023

Sabrina Fischer, Van Tuan Trinh, Clara Simon, Lisa M. Weber, Ignasi Forné, Andrea Nist, Gert Bange, Frank Abendroth, Thorsten Stiewe, Wieland Steinchen, Robert Liefke, Olalla Vázquez
Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells.

Lutz V, Hellmund VM, Picard FSR, Raifer H, Ruckenbrod T, Klein M, Bopp T, Savai R, Duewell P, Keber CU, Weigert A, Chung HR, Buchholz M, Menke A, Gress TM, Huber M, Bauer C
IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model.

Roschenko V, Ayoub AM, Engelhardt K, Schäfer J, Amin MU, Preis E, Mandic R, Bakowsky U
Lipid-Coated Polymeric Nanoparticles for the Photodynamic Therapy of Head and Neck Squamous Cell Carcinomas.

Hoffmann J, Thrun MC, Röhnert MA, von Bonin M, Oelschlägel U, Neubauer A, Ultsch A, Brendel C
Identification of critical hemodilution by artificial intelligence in bone marrow assessed for minimal residual disease analysis in acute myeloid leukemia: The Cinderella method.

Hoffmann J, Eminovic S, Wilhelm C, Krause SW, Neubauer A, Thrun MC, Ultsch A, Brendel C
Prediction of Clinical Outcomes with Explainable Artificial Intelligence in Patients with Chronic Lymphocytic Leukemia.

Picard FSR, Lutz V, Brichkina A, Neuhaus F, Ruckenbrod T, Hupfer A, Raifer H, Klein M, Bopp T, Pfefferle PI, Savai R, Prinz I, Waisman A, Moos S, Chang HD, Heinrich S, Bartsch DK, Buchholz M, Singh S, Tu M, Klein L, Bauer C, Liefke R, Burchert A, Chung HR, Mayer P, Gress TM, Lauth M, Gaida M, Huber M
IL-17A-producing CD8+ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts.

Palmowski J, Kohnhorst S, Bauer P, Puta C, Haunhorst S, Gebhardt K, Reichel T, Keller C, Huber M, Raifer H, Krüger K
T-cell-derived TNF-α and a cluster of immunological parameters from plasma allow a separation between SARS-CoV-2 convalescent versus vaccinated elite athletes.

2022

Hoffmann J, Etati R, Brendel C, Neubauer A, Mack E
The Low Expression of Fc-Gamma Receptor III (CD16) and High Expression of Fc-Gamma Receptor I (CD64) on Neutrophil Granulocytes Mark Severe COVID-19 Pneumonia.

Raifer H, Schulz AR, Theodorou J, Romero-Olmedo AJ, Böck A, Bertrams W, Schmeck BT, Chung HR,
Lohoff M, Chang HD, Schaub B, Mei HE, Huber M
Mass cytometry-based identification of a unique T-cell signature in childhood allergic asthma

Elisabeth K. M. Mack, Sören Hartmann, Petra Ross, Ellen Wollmer, Christoph Mann, Andreas Neubauer, Cornelia Brendel, Jörg Hoffmann
Monitoring multiple myeloma in the peripheral blood based on cell‑free DNA and circulating plasma cells.