Dates and Events
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Prof. Jörg Stülke, University of Göttingen: Microbial nucleotide metabolism: News from Bacillus subtilis Speaker Series. The Stülke lab studies the regulation of metabolism in the pathogenic bacterium Mycoplasma pneumoniae and the model organism Bacillus subtilis. They are following global (“post-genomic”) and gene-specific approaches. In Bacillus subtilis, metabolism is studied by transcriptomics, metabolome and fluxome analyses. The specific interests are focussed on two key pathways: glycolysis and glutamate biosynthesis, the decisive link between carbon and nitrogen metabolism. The regulation of glycolysis is studied at the level of a controlled protein-RNA interaction. Regulation through RNA has become widely recognized in the past few years. The lab’s studies revealed that glycolytic enzymes themselves are part of a protein complex that is required for mRNA processing and degradation. Interest is also directed at systems biology approaches to the analysis of B. subtilis and the development of web interfaces for the functional annotation.
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Dr. Patricia Bedrunka: Structural and functional characterization of the bacterial biofilm activator RemA PI Lecture
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Prof. Andrea Rentmeister, University of Münster: Improving the 5′ Cap of mRNA by Chemical Modifications Speaker Series. More information coming soon.
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Prof. Aurelio Teleman, German Cancer Research Center, Heidelberg: Non-uniform regulation of epigenetic marks via metabolism in a developing tissue Speaker Series. Abstract: Histone acetylation regulates gene expression, cell function, and cell fate. We studied the pattern of histone acetylation in an epithelial tissue, the Drosophila wing disc and find that H3K18ac, H4K8ac, and total lysine acetylation are elevated in the outer rim of the disc. This is due in part to high fatty acid β-oxidation (FABO) in the rim, and partly due to nuclear positioning. This affects gene expression. In sum, there is a physical mark of the outer rim of the wing and other epithelia in Drosophila.
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Prof. Sonja-Verena Albers, University of Freiburg: New players in FtsZ-based cell division in Archaea Speaker Series. The event is co-hosted by the Microbiology Seminar Series, Max Planck Institute for Terrestrial Microbiology, Marburg, and as such can also be attended online. After the lecture and the public discussion, there will be a Meet & Greet of MiNu's doctoral researchers with Prof. Albers.
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Prof. Martin Thanbichler: Role of NTPases in the spatiotemporal organization of bacterial cells PI Lecture
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Prof. Michal Hocek, Charles University, Prague Speaker Series. More information coming soon.
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Dr. Maria Duca, Université Côte d’Azur Speaker Series. More information coming soon.
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Dr. Katharina Höfer: RNA modifications in bacteria: Discovery and function PI Lecture
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Prof. Olalla Vázquez: Activatable probes for live-cell and in-vivo imagining PI Lecture
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Prof. Lars-Oliver Essen: Theoretical and experimental analysis of structural dynamics PI Lecture
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Dr. Marcus Lechner: 6S RNA - Universal Regulator of Transcription PI Lecture
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Prof. Lennart Randau: CRISPR-based regulation of bacterial gene networks PI Lecture
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Dr. Murat Sunbul, Heidelberg University: Illuminating biology with fluorescent RNAs Speaker Series. After the lecture, MiNu's doctoral researchers will have the opportunity for discussions with Dr. Sunbul.
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2024 Summer Symposium Invited speakers: Prof. Iwona Mruk (University of Gdansk), Prof. Ben Luisi (University of Cambridge), Dr. Georg Hochberg (MPI Marburg), Dr. Rebecca Hinrichs (University of Marburg), Prof. Kristina Jonas (Stockholm University), Prof. Urs Jenal (University of Basel).
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2024 Retreat Annual closed meeting of MiNu's doctoral students, PIs and selected external researchers
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Dr. Maximilian Ulbrich, University of Freiburg: Single-molecule imaging of membrane protein interactions in living cells Speaker Series. Background information: the Ulbrich Lab is part of the BIOSS Centre for Biological Signalling Studies and the Faculty of Medicine at the University of Freiburg, and a member of the Spemann Graduate School of Biology and Medicine. Research in the Ulbrich Lab lab focusses on interactions of membrane proteins in living cells, trying to understand how complexes made of many different proteins assemble and how they behave during signalling processes. To this purpose, single fluorescent molecules are imaged using state-of-the art microscopy equipment and develop novel tools for single molecule imaging. Current projects include the dynamic behaviour of G protein-coupled receptors, the assembly of glutamate receptors with their auxiliary subunits, and super-resolution imaging.
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Workshop Week Symposium With talks by Dr. Benedict Tan (Pharmaceutical Chemistry, University of Marburg), Prof. Kai Thormann (Microbiology, University of Gießen), Dr. Patricia Bedrunka (SYNMIKRO, PI of GRK 2937's Project 9, University of Marburg) and Prof. Haike Antelmann (Microbiology, University of Berlin).