28.09.2026 IPPF Scientific Symposium on Pemphigus & Pemphigoid in Lübeck

Live from the 2026 IPPF Scientific Symposium on Pemphigus & Pemphigoid in Lübeck - our speaker Michael Hertl talks about Pemphigus, the pathogenesis and evolving therapeutic targets!

Also on stage from our consortium:
Ralf Ludwig, Enno Schmidt, Jens Waschke as organizers and chairs

  • 👩‍🔬 Franziska Vielmuth on "A Mutation in the Binding Pocket of Desmogleins Impacts Dsg2-Dsg3 Related Desmosome Signaling in Keratinocytes in Pemphigus" (Session 1)
  • 👩‍🔬 Anna Sigmund on "Strengthened Desmosome-Keratin Anchorage by Myosin Activation as a Novel Therapeutic Approach for Pemphigus Vulgaris" (Session 3)
  • 👩‍🔬 Shafaq Riaz on "Immunomodulatory Effects of IL-23p19 and IL4Ra Blockade in Novel Desmoglein3-Specific B-Cell Driven Transgenic Mouse Model of Pemphigus Vulgaris" (Session 6)
  • 👩‍🔬 Shirin Emtenani on "MEK1/2 Inhibition Ameliorates Clinical Lesions in Experimental Pemphigus Vulgaris" (Session 6)

DEFINE - SFB/TRR 425 members are not only on stage, but also presenting posters: 

  • #16 Ibrutinib ameliorates disease severity in a mouse model of anti-BP180 mucous membrane pemphigoid 
    Shirin Emtenani
  • #23 AK23 blocks homophilic Dsg3 binding in desmosomes of a novel Dp-EYFP desmosome reporter mouse model
    Dr. Michael Fuchs
  • #34 Immunomodulatory Effects of IL-23p19 and IL4Ra Blockade in Novel Desmoglein3-Specific B-Cell Driven Transgenic Mouse Model of Pemphigus Vulgaris
    Shafaq Riaz 
  • #45 Depletion of regulatory T cells breaks self-tolerance and induces epidermolysis bullosa acquisita in resistant C57BL/6J mice
    Manuela Pigors 
  • #56 Subclass-Specific Kinase Signatures in Pemphigus: IgG4 as a Distinct Pathogenic Driver
    Nancy Ernst 
  • #57 Deciphering the signaling events in Dsg1 and Dsg3 antibody-induced pathology
    Nancy Ernst 
  • #79 Impact of different IgG subclasses and glycosylation forms on immune complex-induced signaling in neutrophils in epidermolysis bullosa acquisita
    Nancy Ernst 
  • #114 Immunoregulatory functions of Natural killer cells in patients with pemphigus vulgaris
    Bárbara Betônico Berg

Cooperation Partners