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6th International TRR 81 Symposium on
"Chromatin Changes in Differentiation and Malignancies"

- 27th to 29th of September 2022 in Egmond aan Zee, The Netherlands -

- Registration ended -

Accommodation for TRR81 members and speakers will be provided.
For external participants: Please consider booking a room at our venue.


Cellular transcription programmes undergo profound changes both during differentiation of healthy cells and during the malignant transformation of diseased cells. This modulation of transcriptional outputs is orchestrated by changes in chromatin structure that operate at different yet interconnected levels: they affect the arrangement of the genome in the nuclear space, the activity and accessibility of enhancers and other regulatory elements, and the function of transcription factors, chromatin-associated proteins, enzymes acting on chromatin, and RNA. Recent advances have expanded our understanding of the underlying molecular processes but also have raised many new questions.

The 6th TRR 81 symposium on “Chromatin Changes in Differentiation and Malignancies” will provide a comprehensive view of the state-of-the-art and offer the opportunity for discussion with international leaders in the field.

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