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AG Vegetative Physiologie


Prof. Dr. Niels Decher

Adresse:
Deutschhausstraße 1-2
35037 Marburg
Mail: decher@staff.uni-marburg.de
Tel: 06421/ 28-62 148
Fax: 06421/ 28-66 659



 

 

 

AG Vegetative Physiologie

Selected publications:

Schindler RFR, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon K-L, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T & Ferlini A. (2016).
POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking.
J. Clin. Invest. 126: 239-53.

§Friedrich C, §Rinné S, Zumhagen S, Kiper AKSilbernagel NNetter MF, Stallmeyer B, Schulze-Bahr E & *Decher N. (2014).
Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder.
EMBO Mol. Med. 6: 937-951.   §shared first authors, *corresponding author

Marzian S,
 Stansfeld PJ, Rapedius M, Rinné S, Nematian-Ardestani E, Abbruzzese JL, Steinmeyer K, Sansom MSP, Sanguinetti MC, Baukrowitz T & *Decher N. (2013).
Side pockets provide the basis for a new mechanism of Kv channel–specific inhibition.
Nature Chem. Biol. 9: 507-513. *corresponding author

Froese A, Breher SS, Waldeyer C, Schindler RF, Nikolaev VO, Rinné S, Wischmeyer E, Schlueter J, Becher J, Simrick S, Vauti F, Kuhtz J, Meister P, Kreissl S, Torlopp A, Liebig SK, Laakmann S, Müller TD, Neumann J, Stieber J, Ludwig A, Maier SK,Decher N, Arnold HH, Kirchhof P, Fabritz L & Brand T (2012). 
Popeye domain containing proteins are essential for stress-mediated modulation of cardiac pacemaking in mice.
J. Clin. Invest.   122: 1119-30.

Piechotta PL, Rapedius M, Stansfeld PJ, Bollepalli MK, Erhlich G, Andres-Enguix I, Fritzenschaft H, Decher N, Sansom MS, Tucker SJ & Baukrowitz T. (2011).
The pore structure and gating mechanism of K2P channels.
EMBO J. 30: 3607-3619.

*Decher N, Streit AK, Rapedius M, Netter MF, Marzian S, Ehling P, Schlichthörl G, Craan T, Renigunta V, Köhler A, Dodel RC, Navarro-Polanco RA, Preisig-Müller R, Klebe G, Budde T, Baukrowitz T & Daut J. (2010).
RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels.
EMBO J. 29: 2101-2113. *corresponding author

*Decher N, Gonzalez T, Streit AK, Sachse F, Renigunta V, Soom M, Heineman SH, Daut J & Sanguinetti MC. (2008).
Structural determinants of Kvß1 induced channel inactivation: a PIP2 modulated hairpin.
EMBO J. 27: 3164-3174. *corresponding author

Splawski I, Timothy KW, Decher N, Kumar P, Sachse FB, Beggs AH, Sanguinetti MC & Keating MT. (2005).
Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations.
Proc. Natl. Acad. Sci. USA 102: 8089-8096.

Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC & Keating MT. (2004).
CaV1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Cell   119: 19-31.

 

Zuletzt aktualisiert: 26.01.2016 · Susanne Bamerny

 
 
Fb. 20 - Medizin

Institut für Physiologie und Pathophysiologie, Deutschhausstraße 1-2, D-35037 Marburg
Tel. +49 6421/28-66495, Fax +49 6421/28-68960, E-Mail: bamerny@staff.uni-marburg.de

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