Research Groups

• Adhikary Lab We study how transcription is regulated in disease as well as its modulation by druggable factors, in particular by nuclear receptors.
• Bauer Lab We are investigating the epigenetic and gene-regulatory functions of protein arginine methyltransferases (PRMTs) in mammalian cells.
• Bouazoune Team We are interested in understanding how chromatin/epigenetic factors regulate genome functions, at the molecular level. In addition, we investigate how mutation of these factors contribute to human diseases.
• Brehm Group We maintain a large scale fly culture and are combining biochemical, genetic and molecular biology approaches to investigate conserved tumour suppressor complexes and chromatin regulators.
• Liefke Lab We aim to better understand the regulatory mechanisms of the polycomb repressive complex 2 (PRC2) in a physiological and pathophysiological context. In particular we want to better understand the role of PRC2-associated factors in stem cell biology and cancer.
• Mermoud Lab We wish to understand the chromatin-based mechanisms which control the identity and fate of mammalian cells.