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Publications

Roles and regulation of endogenous retroviruses in pluripotency and early development. 
Sharon Schlesinger, Miguel R. Branco and Mermoud J.E. 
Stem Cell Epigenetics, Volume 17 in Translational Epigenetics p 155-186 (2020) 
  

SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells.
Sachs P., Ding D., Bergmaier P., Lamp B., Schlagheck C., Finkernagel F., Nist A., Stiewe T. and Mermoud J.E.
Nature Communications Volume 10, Article number: 1335 (2019)
https://rdcu.be/bvlZZ

  

The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes.
Ding, D., Bergmaier, P., Sachs P., Klangwart M., Rückert T., Bartels N., Demmers J., Dekker M., Poot R.A. and Mermoud J.E.
J. Biol. Chem. (2017) doi:10.1074/jbc.RA117.000959
Selected to appear in a special virtual issue on “Pluripotency regulation and differentiation” at JBC http://www.jbc.org/site/vi/

  

Keeping chromatin quiet: how nucleosome remodeling restores heterochromatin after replication.
Mermoud J.E. , Rowbotham, S.P. and Varga-Weisz, P.
Cell Cycle. Extra View. (2011) 10(23):4017-4025.

  

Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.
Rowbotham, S.P., Barki L., Neves-Costa, A., Santos, F., Dean, W., Hawkes, N., Choudhary P, Will W.R., Webster, J., Oxley, D., Green, C.M., Varga-Weisz, P. and Mermoud J.E.
Mol. Cell (2011) 42, 285-296.

· Previewed in Mol Cell. 42, 267-269, by Jasencakova and Groth
  

Neurite-like structures induced by mevalonate pathway blockade are due to the stability of cell adhesion foci and are enhanced by the presence of APP.
Hughes, M., Snetkov V., Rose R.S., Trousil S., Mermoud J.E., Dingwall C.
J. Neurochem. (2010) 114 (3), 832-842.

  

Epigenomes under scrutiny. Report on the 3rd UK Stem Cell Meeting.
Mermoud J.E.
Genome Biol. (2008) 9:308.

  

Global hypomethylation of the genome in XX ES cells.
Zvetkova, I., Apedaile, A., Ramsahoye, B., Mermoud J.E., Crompton, L., John, R., Feil, R. and Brockdorff N.
Nat Genet. (2005) 37, 1274-1279.

  

Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation.
de Napoles, M., Mermoud J.E., Wakao R., Tang Y.A., Endoh M., Appanah R., Nesterova T.B., Silva J., Otte A.P., Vidal M., Koseki H. and Brockdorff N.
Dev Cell. (2004) 7, 663-676.

  

Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.
Mermoud J.E., Popova, B., Peters A.H.F.M., Jenuwein T. and Brockdorff N.
Current Biol. (2002) 12, 247-251.

  

Xist expression and macroH2A1.2 localisation in mouse primordial and pluripotent embryonic germ cells.
Nesterova, T.B., Mermoud J.E., Hilton K., Pehrson J.R., Surani, M.A., McLaren, A. and Brockdorff N.
Differentation (2002) 69, 216-225.

  

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.
Peters A.H.F.M., Mermoud J.E., O'Carroll D., Pagani M., Schweizer D., Brockdorff N. and Jenuwein T.
Nat Genet. (2002) 30, 77-80.

  

Centrosomal association of histone macroH2A1.2 in embryonic stem cells and somatic cells.
Mermoud J.E., Tassin A.M., Pehrson J.R. and Brockdorff N.
Exp Cell Res. (2001) 268, 245-251.

  

Histone macroH2A1.2 relocates to the inactive X chromosome after initiation and propagation of X inactivation.
Mermoud, J.E., Constanzi, C., Pehrson, J.R. and Brockdorff, N.
J. Cell. Biol. (1999) 147, 1399-1408.

  

Cis acting elements distinct from the 5´ splice site promote U1-independent pre-mRNA splicing.
Crispino, J.D., Mermoud, J.E., Lamond, A.I. and Sharp, P.A.
RNA 2 (1996) 664-674.

  

Uncovering the role of Ser/Thr protein phosphorylation in nuclear pre-mRNA splicing.
Mermoud, J.E., Calvio, C. and Lamond, A.I.
Adv. Prot. Phosphatases (1994) 8, 105-125. Review

  

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.
Mermoud, J.E., Cohen, P.T.W. and Lamond, A.I.
EMBO J. (1994) 13, 5679-5688.

  

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing.
Mermoud, J.E. Cohen, P. and Lamond, A.I.
Nucleic Acids Res. (1992) 20, 5263-5269.


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