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Prevention in Parkinson's Disease (PiP) – A Multidimensional Lifestyle Intervention for Individuals with Prodromal and Clinical Parkinson's Disease

Description

As no disease-modifying therapy is available for Parkinson's disease, preventive measures and the use of compensatory and reserve mechanisms are becoming increasingly important. In particular, lifestyle factors such as regular physical activity, a balanced diet, adequate sleep, and cognitive training may delay the onset of Parkinson's disease and have already been scientifically linked to a more favorable disease course.

The aim of this study is to investigate whether a six-month, multidimensional lifestyle program is well accepted and can be sustained long-term by individuals with prodromal or clinical Parkinson's disease. Adherence of the participants is used as the primary endpoint. The intervention comprises supervised physical training, nutritional counseling, sleep counseling, and cognitive training. In addition to the primary endpoint, changes in clinical symptoms and biological markers are assessed and evaluated as secondary endpoints.

The results are intended to contribute to the development of effective prevention strategies for Parkinson's disease and to lay the groundwork for a future large-scale clinical trial.

Contact

Mrs. Dilara Bingöl und Mrs. Lotte Seegräber
Telefon: 06421/58 - 65299
Telefax: 06421/58 - 67055
dilara.bingoel@staff.*

* please add "uni-marburg.de" for a full email-address.