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Publications of the Institute

S. Bogdan
  • Inhalt ausklappen Inhalt einklappen 20212021

    Bischoff M, Bogdan S (2021). Collective cell migration driven by filopodia—New insights from the social behavior of myotubes. BioEssays. https://doi.org/10.1002/bies.202100124

    *Kiper AK, *Bedoya M, *Stalke S, *Marzian S, Ramírez D, Cruz Adl, Peraza DA, Vera-Zambrano A, Márquez Montesinos JCE, Arévalo Ramos BA, Rinné S, Gonzalez T, Valenzuela C, Gonzalez W & #Decher N. (2021). Identification of a critical binding site for local anesthetics in the side pockets of Kv1 channels. Br. J. Pharmacol. In Press. *shared first authors. #corresponding author.

    *,#Decher N, *Rinné S, Bedoya M, González W & Kiper AK. (2021). Molecular pharmacology of K2P potassium channels. Cell. Physiol. Biochem. 55: 87-107. Invited Review. *shared first author. #corresponding author.

    *Oertli A, *Rinné S, Moss KR, Kääb S, Seemann G, Beckmann BM & Decher N. (2021). Molecular mechanism of autosomal recessive long QT-syndrome 1 without deafness. Int. J. Mol. Sci. 22:1112. *shared first author.

    Bischoff, M.C., S. Lieb, R. Renkawitz-Pohl, and S. Bogdan. (2021). Filopodia-based contact stimulation of cell migration drives tissue morphogenesis. Nature Communications 12:791.

    Wiedmann F, Rinné S, Donner B, Decher N, Katus HA & Schmidt C (2021). Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system. Prog Biophys Mol Biol Jan;159:126-135.

  • Inhalt ausklappen Inhalt einklappen 20202020

    *Endres D, *Decher N, Röhr I, Vowinkel K, Domschke K, Komlosi K, Tzschach A, Gläser B, Schiele M, Runge K, Süß P, Schuchardt F, Nickel K, Stallmeyer B, Rinné S, Schulze-Bahr E & Tebartz van Elst L. (2020). New Cav1.2 Channelopathy with high-functioning autism, affective disorder, severe dental enamel defects, a short QT interval, and a novel CACNA1C loss-of-function mutation. Int. J. Mol. Sci. 21: 8611. * shared first author.

    Erlenhardt N, Kletke O, Wohlfarth F, Komadowski MA, Clasen L, Makimoto H, Rinné S, Kelm M, Jungen C, Decher N, Meyer C & Klöcker N. (2020). Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking. Pflügers Archive.  472: 1733-1742.

    Rinné S, Ortiz-Bonnin B, Stallmeyer B, Kiper AK, Fortmüller L, Schindler RFR, Herbort-Brand U, Kabir NS, Dittmann S, Friedrich C, Zumhagen S, Gualandi F, Selvatici R, Rapezzi C, Arbustini E, Ferlini A, Fabritz L, Schulze-Bahr E, Brand T & *Decher N. (2020). POPDC2 a novel susceptibility gene for conduction disorders. J. Mol. Cell Cardiol.  145: 74-83. *corresponding author.

    Lindner M, Gilhooley MJ, Peirson SN, Hughes S, Hankins MW (2020). The functional characteristics of optogenetic gene therapy for vision restoration. Cell. Mol. Life Sci Jul 29.

    Pfau M, von der Emde L, Dysli C, Möller PT, Thiele S, Lindner M, Schmid M, Rubin DL, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2020). Determinants of Cone and Rod Functions in Geographic Atrophy: AI-Based Structure-Function Correlation. Am. J. Ophthalmol 217:162-73.

    Zou X, Conrad LJ, Koschinsky K, Schlichthörl G, Preisig-Müller R, Netz E, Krüger J, Daut J, Renigunta V (2020). The Phosphodiesterase Inhibitor IBMX Blocks the Potassium Channel THIK-1 from the Extracellular Side. Mol Pharmacol 98:143-55.

    #Rödström KEJ, #Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, Burgess-Brown NA, Tucker SJ, Mueller T, *Decher N & *Carpenter EP (2020). A lower X-gate in TASK channels traps inhibitors within the vestibule. Nature Jun;582(7812):443-447. *Shared senior and corresponding authors. #Shared first authors.

    Lindner M, Gilhooley MJ, Palumaa T, Morton AJ, Hughes S, Hankins MW (2020). Expression and Localization of KCNE2 in the Vertebrate Retina. Invest. Ophtalmol. Vis. Sci 61:33.

    Bustos D, Bedoya M, Ramirez D, Concha G, Zúñiga L, Decher N, Hernandez EW, Sepúlveda FV, Martinez L & González W (2020). Elucidating the structural basis of the intracellular pH sensing mechanism of TASK-2 K2P channel. Int. J. Mol. Sci 21: E532.

    Perniss A, Liu S, Boonen B, Keshavarz M, Ruppert AL, Timm T, Pfeil U, Soultanova A, Kusumakshi S, Delventhal L, Aydin Ö, Pyrski M, Deckmann K, Hain T, Schmidt N, Ewers C, Günther A, Lochnit G, Chubanov V, Gudermann T, Oberwinkler J, Klein J, Mikoshiba K, Leinders-Zufall T, Offermanns S, Schütz B, Boehm U, Zufall F, Bufe B, Kummer W (2020). Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides. Immunity Apr 14;52(4):683-699.e11.

    Rust K and Nystul TG. (2020) ‘Signal transduction in the early Drosophila follicle stem cell lineage’, Current Opinion in Insect Science, 37, pp. 39–48.

    Rust K, Byrnes LE, Shengyang K, Park JS, Sneddon JB, Tward AD, Nystul TG. (2020) ‘A Single-Cell Atlas and Lineage Analysis of the Adult Drosophila Ovary’, Nature Communications 11(1):5628

  • Inhalt ausklappen Inhalt einklappen 20192019

    Dierich M, Hartmann S, Dietrich N, Moeser P, Brede F, Johnson Chacko L, Tziridis K, Schilling A, Krauss P, Hessler S, Karch S, Schrott-Fischer A, Blumer M, Birchmeier C, Oliver D, Moser T, Schulze H, Alzheimer C, Leitner MG, Huth T (2019). β-secretase BACE1 is required for normal cochlear function. The Journal of Neuroscience Nov 6;39(45):9013-9027 (coverpicture).

    Dierich M, van Ham WB, Stary-Weinzinger A, Leitner MG (2019). Histidine at position 462 determines the low quinine sensitivity of ether-a-go-go channel superfamily member Kv 12.1. Br J Pharmacol 176:2708-2723.

    Chang Y-N, Jaumann EA, Reichel K, Hartmann J, Oliver D, Hummer G, Joseph B, Geertsma ER (2019). 
    Structural basis for functional interactions in dimers of SLC26 transporters. Nature Communications 10:2032.
     
    Leitner MG, Oliver D (2019). A choreography of intracellular Ca(2+) and extracellular ATP to refine auditory nociceptors before hearing. EMBO J May 2;38(9):e101980.
     
    Leitner MG, Thallmair V, Wilke BU, Neubert V, Kronimus Y, Halaszovich CR, Oliver D (2019). The N-terminal homology (ENTH) domain of Epsin 1 is a sensitive reporter of physiological PI(4,5)P2 dynamics. BBA - Mol Cell Biol Lipids 1864:433-442.

    Horsthemke, M., Nutter, L.M.J., Bachg, A.C., Skryabin, B.V., Honnert, U., Zobel, T., Bogdan, S., Stoll, M., Seidl, M.D., Mueller, F.U., et al. (2019). A novel isoform of myosin 18A (Myo18Agamma) is an essential sarcomeric protein in mouse heart. J Biol Chem. 3;294(18):7202-7218.

    Stuerner, T., Tatarnikova, A., Mueller, J., Schaffran, B., Cuntz, H., Zhang, Y., Nemetova, M., Bogdan, S., Small, V. and Tavosanis, G. (2019). Transient localization of the Arp2/3 complex initiates neuronal dendrite branching in vivo. Development Apr 4;146(7):dev171397.

    Bedoya M, Rinné S, Kiper AKDecher N, González W, Ramírez D. (2019). TASK Channels Pharmacology: New Challenges in Drug Design. J Med Chem 62(22):10044-10058.

    Ramírez D*, Bedoya M, Kiper AK, Rinné S, Morales-Navarro S, Hernández-Rodríguez EW, Sepúlveda FV, Decher N* & González W*. (2019). Structure/activity analysis of TASK-3 channel antagonists based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine. Int. J. Mol. Sci 7;20(9):2252. *shared corresponding author  *shared corresponding author 

    Wiedmann F, Kiper AK, Bedoya M, Ratte A, Rinné S, Kraft M, Waibel M, Anad P, Wenzel W, Gonzalez W, Katus HA, Decher N* & Constanze Schmidt*. (2019). Identification of the A293 (AVE1231) binding site in the cardiac two-pore domain potassium channel TASK-1: a common low affinity antiarrhythmic drug binding site. Cell. Physiol. Biochem. 52: 1223-1235.  *shared senior and corresponding author

    Rinné S, Kiper AK, Vowinkel KS, Ramírez D, Schewe M, Bedoya M, Aser D, Gensler I, Netter MF, Stansfeld PJ, Baukrowitz T, González W & Decher N*. (2019). The molecular basis for an allosteric inhibition of K+-flux gating in K2P channels. eLIFE. Feb 26: 8.  *corresponding author

    Schewe M, Sun H,  Mert Ü, Mackenzie A, Pike  ACW, Schulz F, Constantin C, Vowinkel KS, Conrad LJ,  Kiper AK, Gonzalez W, Musinszki M, Tegtmeier M, Pryde DC, Belabed H,  Nazare M, de Groot BL, Decher N, Fakler B, Carpenter EP, Tucker SJ & Baukrowitz T. (2019). A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels. Science. 363: 875-880.

    Key J, Mueller A-K, Gispert S, Matschke L, Wittig I, Corti O, Münch C, Decher N* & Auburger G*. (2019).
    Ubiquitylome profiling of Parkin-null brain reveals dysregulation of calcium homeostasis factors ATP1A2,Hippocalcin and GNA11, reflected by altered firing of noradrenergic neurons. Neurobiol. Dis 127:114-130.   *shared corresponding authors
     

    Kuß J, Stallmeyer B, Hain E, Goldstein M, Rinné S, Pees C, Zumhagen S, Seebohm G, Decher N, Pott L, Kienitz M-C & Schulze-Bahr E. (2019). Familial sinus node disease caused by a gain of GIRK channel function. Circ. Genom. Precis. Med. 12: e002238.

  • Inhalt ausklappen Inhalt einklappen 20182018

    Hackelberg S, Oliver D (2018) Metabotropic Acetylcholine and Glutamate Receptors mediate PI(4,5)P2 Depletion and Oscillations in Hippocampal CA1 Pyramidal Neurons in situ. Sci Rep Aug 28;8(1):12987.

    Dierich M, Leitner MG (2018) Kv12.1 channels are not sensitive to GqPCR-triggered activation of phospholipase Cβ. Channels 12:228-239.

    Leitner MG, Hobiger K, Mavrantoni A, Feuer A, Oberwinkler J, Oliver D, Halaszovich CR (2018) A126 in the active site and TI167/168 in the TI loop are essential determinants of the substrate specificity of PTEN. Cell Mol Life Sci 75:4235-4250.     
     
    Dierich M, Evers S, Wilke BU, Leitner MG (2018) Inverse Modulation of Neuronal Kv12.1 and Kv11.1 Channels by 4-Aminopyridine and NS1643. Front Mol Neurosci 11:11.      

    Qi Y, Mair N, Kummer KK, Leitner MG, Camprubi-Robles M, Langeslag M, Kress M (2018) Identification of Chloride Channels CLCN3 and CLCN5 Mediating the Excitatory Cl(-) Currents Activated by Sphingosine-1-Phosphate in Sensory Neurons. Front Mol Neurosci 11:33.

    Scherzinger, A., Hugenroth, P., Rüder, M., Bogdan, S. and Jiang, X. (2018). Multi-class Cell Segmentation using CNNs with F1-measure Loss Function. Contributed to the Proc. of 40th German Conference on Pattern Recognition (GCPR), Stuttgart.

    Rüder M, Nagel BM, Bogdan S. (2018). Analysis of Cell Shape and Cell Migration of Drosophila Macrophages In Vivo. Methods Molecular Biology Vol. 1749, 978-1-4939-7700-0.

    Soufi M, Ruppert V, Rinné S, Mueller T, Kurt B, Pilz G, Maieron A, Dodel R, Decher N & Schaefer JR. (2018). Increased KCNJ18 promoter activity as a mechanism in atypical normokalemic periodic paralysis. Neurol. Genet. 4: e274.

    Möller M, Silbernagel N, Wrobel E, Stallmayer B, Amedonu E, Rinné S,  Peischard S, Meuth SG, Wünsch B, Strutz-Seebohm N, Decher N, Schulze-Bahr E &  Seebohm G. (2018). In vitro analyses of novel HCN4 gene mutations. Cell. Physiol. Biochem. 49: 1197-1207. 

    Silbernagel N, Walecki M,  Schäfer  MK-H, Kessler M, Zobeiri M, Rinné S, Kiper AK, Komadowski MA, Vowinkel KS, Wemhöner K, Fortmüller L, Schewe M, Dolga AM, Scekic‑Zahirovic J, Matschke LA, Culmsee C, Baukrowitz T, Monassier L, Ullrich ND, Dupuis L, Just S, Budde T, Fabritz L & Decher N.* (2018).  The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function. FASEB J. 32: 6159-6173. *corresponding author

    Pott A, Bock S, Berger IM, Frese K, Dahme T, Kessler M, Rinné S, Decher N, Just S & Rottbauer W. (2018). Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish. 
    J. Mol. Cell. Cardiol.  120: 42–52.

    Henrich MT, Geibl FF, Lee B, Chiu W-H, Koprich JB, Brotchie JM, Timmermann L, Decher N, §Matschke LA & §Oertel WH. (2018). A53T-α-synuclein overexpression in murine locus coeruleus induces Parkinson's disease-like pathology in neurons and glia. Acta. Neuropathol. Commun. 6: 39. §shared last authors

    *Matschke LA, Rinné S, Snutch TP, Oertel WH, Dolga AM & *Decher N. (2018). Calcium-activated SK potassium channels are key modulators of the pacemaker frequency in locus coeruleus neurons. Mol. Cell. Neuroci. 88: 330–341. *corresponding authors

  • Inhalt ausklappen Inhalt einklappen 20172017

    Vogl C, Butola T, Haag N, Hausrat TJ, Leitner MG, Moutschen M, Lefebvre PP, Speckmann C, Garrett L, Becker L, Fuchs H, Hrabe de Angelis M, Nietzsche S, Kessels MM, Oliver D, Kneussel M, Kilimann MW, Strenzke N (2017) The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Rep 18:2015-2029.

    Dembla, S., M. Behrendt, F. Mohr, C. Goecke, J. Sondermann, F. M. Schneider, M. Schmidt, J. Stab, R. Enzeroth, M. G. Leitner, P. Nunez-Badinez, J. Schwenk, B. Nurnberg, A. Cohen, S. E. Philipp, W. Greffrath, M. Bunemann, D. Oliver, E. Zakharian, M. Schmidt and J. Oberwinkler (2017). Anti-nociceptive action of peripheral mu-opioid receptors by G-beta-gamma protein-mediated inhibition of TRPM3 channels. Elife Aug 15;6:e26280.

    Constantin CE, Müller CS, Leitner MG, Bildl W, Schulte U, Oliver D, Fakler B (2017) Identification of Cav2–PKCβ and Cav2–NOS1 complexes as entities for ultrafast electrochemical coupling. Proc Natl Acad Sci USA 114:5707-5712.
      
    Santos-Sacchi J, Navaratnam D, Raphael RM, Oliver D (2017) Prestin - molecular mechanisms underlying outer hair cell electromotility. In: Understanding the cochlea (Manley GA, Gummer AW, eds). New York: Springer.

    Nagel BM, Bechtold M, Rodriguez LG, Bogdan S. (2017). Drosophila WASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization. Journal of cell Science  130: 344-359, cover picture.

    Rottner K, Faix J, Bogdan S, Linder S, Kerkhoff E. (2017). Actin assembly mechanisms at a glance. Journal of Cell Science  Oct 15;130(20):3427-3435.

    Brüser L, Bogdan S. (2017). Molecular Control of Actin Dynamics In Vivo: Insights from Drosophila. Handbook of experimental pharmacology  235: 285-310.

    Rothenbusch-Fender S, Fritzen K, Bischoff MC, Buttgereit D, Oenel SF, Renkawitz-Pohl R (2017). Myotube migration to cover and shape the testisof Drosophila depends on Heartless, Cadherin/Catenin, and myosin II. Biology Open. Dec 15;6(12):1876-1888

    Brüser L, Bogdan S. (2017). Adherens Junctions on the Move-Membrane Trafficking of E-Cadherin. Cold Spring Harb Perspect Biol Mar 1;9(3):a029140.

    Rinné S, Kiper AK, Schmidt C, Ortiz-Bonnin B, Zwiener S, Seebohm G & *Decher N. (2017). Stress-Kinase Regulation of TASK-1 and TASK-3. Cell. Physiol. Biochem.  44: 1024-1037. *corresponding author 

    Leist M, Rinné S, Datunashvili M, Aissaoui A, Pape H-C, Decher N, Meuth SG & Budde T. (2017). Acetylcholine-dependent upregulation of TASK-1 channels in thalamic interneurons by a smooth muscle-like signalling pathway. J. Physiol.  595: 5875-5893. 

    see also Perspectives by Kim D. (2017). Endocytosis: another pathway in receptor-Gq-TASK signalling.

    *Decher N, Kiper AK  & Rinné S. (2017). Stretch-activated potassium currents in the heart: focus on TREK-1 and arrhythmias. Prog. Biophys. Mol. Biol. 130: 223-232. Invited Review.  *corresponding author

    Ramirez D, Arévalo B, Martínez G, Rinné S, Sepúlveda F, *Decher N & *González W. (2017). Side fenestrations provide an `anchor´ for a stable binding of A1899 to the pore of TASK-1 potassium channels. Mol. Pharm.  14: 2197-2208.  *corresponding authors

    Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N,  Culmsee C & Dolga A. (2017). SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake. Cell. Death Differ.  24: 761-773.

    *Decher N, Ortiz-Bonnin B, Friedrich C, Schewe M, Kiper AK, Rinné S, Seemann G, Peyronnet R, Zumhagen S, Bustos D, Kockskämper J, Kohl P, Just S, González W, Baukrowitz T, Stallmeyer B & Schulze-Bahr E. (2017).  Sodium permeable and `hypersensitive´ TREK-1 channels cause ventricular tachycardia. EMBO Mol. Med. 9: 403-414. *corresponding author

    see also Editorial by Goldstein SA. (2017). Sodium leak through K2P potassium channels and cardiac arrhythmia, an emerging theme

    Stallmeyer B, Kuß J, Kotthoff S, Zumhagen S, Vowinkel K, Rinné S, Matschke LA, Friedrich C, Schulze-Bahr E, Rust S, Seebohm G, Decher N & Schulze-Bahr E. (2017).  A mutation in the G-protein gene GNB2 causes familial sinus node and atrioventricular conduction dysfunction. Circ. Res.  120: e33-e44.

  • Inhalt ausklappen Inhalt einklappen 20162016

    Leitner MG, Michel N, Behrendt M, Dierich M, Sembla S, Wilke BU, Konrad M, Lindner M, Oberwinkler J, Oliver D (2016) Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122. Br J Pharmacol 173:2555-69. doi:10.1111/bph.13538

    Squarr AJ, Brinkmann K, Chen B, Steinbacher T, Ebnet K, Rosen MK, Bogdan S. (2016). Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation.  Journal of Cell Biology, Volume 212, No 5, Feb. 29, cover picture. 

    Brinkmann, K., Schulz J., Önel, S.-F., Faix, J, Winterhoff, M. and Bogdan S. (2016). WHAMY is a novel actin polymerase promoting myoblast fusion, macrophage cell motility and sensory organ development in Drosophila. Journal of Cell Science, Volume 129 Issue 3, 604-620, cover picture.

    Hamp J, Löwer A, Dottermusch-Heidel C, Beck L, Moussian B, Flötenmeyer M, Önel SF. Drosophila Kette coordinates myoblast junction dissolution and the ratio of Scar-to-WASp during myoblast fusion. Journal of Cell Science,    2016 Sep 15;129(18):3426-36. Epub 2016 Aug 12.

    Oezel L, Then H, Jung AL, Jabari S, Bonaterra GA, Wissniowski TT, Önel SF, Ocker M, Thieme K, Kinscherf R, Di Fazio P. (2016) Fibromyalgia syndrome: metabolic and autophagic processes in intermittent cold stress mice. Pharmacol Res Perspect. Sep 27;4(5):e00248. eCollection 2016 Oct.

    Ortiz-Bonnin B, Rinné S, Moss R, Streit AK, Scharf M, Richter K, Stöber A, Pfeufer A, Seemann G, Kääb S, Beckmann BM & *Decher N. (2016). Electrophysiological characterization of a large set of novel variants in the SCN5A-gene: Identification of novel LQTS3 und BrS mutations. Pflügers Archiv. 468: 1375-1387. *corresponding author

    Goldstein M, Rinné S, Kiper AK, Ramírez D, Netter MF, Bustos D, Ortiz-Bonnin B, González W & *Decher N. (2016). Functional mutagenesis screens reveal the `cap structure´ formation in disulfide-bridge free TASK channels. Sci. Rep.  6:  19492. *corresponding author

    Schindler RFR, Scotton C, Zhang J, Passarelli C, Ortiz-Bonnin B, Simrick S, Schwerte T, Poon K-L, Fang M, Rinné S, Froese A, Nikolaev VO, Grunert C, Müller T, Tasca G, Sarathchandra P, Drago F, Dallapiccola B, Rapezzi C, Arbustini E, Di Raimo FR, Neri M, Selvatici R, Gualandi F, Fattori F, Pietrangelo A, Li W, Jiang H, Xu X, Bertini E, Decher N, Wang J, Brand T & Ferlini A. (2016). POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking. J. Clin. Invest. 126: 239-253.

  • Inhalt ausklappen Inhalt einklappen 20152015

    Costa HA, Leitner MG, Sos ML, Mavrantoni A, Rychkova A, Johnson JR, Newton BW, Yee M-C, De La Vega FM, Ford JM, Krogan NJ, Shokat KM, Oliver D, Halaszovich CR, Bustamante CD (2015) Discovery and functional characterization of a neomorphic PTEN mutation. Proc Natl Acad Sci USA 112:13976-13981.

    Bista P, Pawlowski M, Cerina M, Ehling P, Leist M, Meuth P, Aissaoui A, Borsotto M, Heurteaux C, Decher N, Pape HP, Oliver D, Meuth SG & Budde T (2015) Differential phospholipase C-dependent modulation of TWIK-related acid-sensitive K+ (TASK) and TWIK-related K+ (TREK) channels in rat thalamocortical relay neurons. J Physiol 593:127-144.

    Kavlie RG, Fritz JL, Nies F, Göpfert MC, Oliver D, Albert JT, Eberl DF (2015) Prestin is an anion transporter dispensable for mechanical feedback amplification in Drosophila hearing. J Comp Physiol A 201:51-60.

    Mavrantoni A, Thallmair V, Leitner MG, Schreiber DN,  Oliver D, Halaszovich CR (2015) A method to control phosphoinositides and to analyze PTEN function in living cells using voltage sensitive phosphatases. Front Pharmacol 6:68. 

    Rjasanow A, Leitner MG, Thallmair V, Halaszovich CR, Oliver D (2015) Ion channel regulation by phosphoinositides analyzed with VSPs – PI(4,5)P2 affinity, phosphoinositide selectivity, and PI(4,5)P2 pool accessibility. Front Pharmacol 6:127.

    Tóth BI, Konrad M, Ghosh D, Mohr F, Halaszovich CR, Leitner MG, Vriens J, Oberwinkler J, Voets T (2015) Regulation of the transient receptor potential channel TRPM3 by phosphoinositides J Gen Physiol 146(1):51-63
     
    Hobiger K, Friedrich T (2015) Voltage sensitive phosphatases: emerging kinship to protein tyrosine phosphatases from structure-function research. Front Pharmacol 6:20. (Review)

    Leitner MG, Halaszovich CR, Ivanova O, Oliver D (2015) Phosphoinositide dynamics in the postsynaptic membrane compartment: Mechanisms and experimental approach. Eur J Cell Biol 94:401-414. (Review)

    Seebach, J., Taha, A., Lenk, J., Lindemann, N., Jiang, X., Brinkmann, K., Bogdan, S. and Schnittler, H.-J. (2015). CellBorderTracker: A Video Analysis Package for the quantification of complex cell junction dynamics in endothelium.  Histochem Cell Biol.  2015 144(6):517-32, cover picture.

    Zobel, T., Brinkmann K., Koch N., Schneider K., Seemann E., Kessels, M., Qualmann, B. and Bogdan, S. (2015). Cooperative functions of the two F-BAR proteins Cip4 and Nostrin in regulating E-cadherin in epithelial morphogenesis. Journal of Cell Science, Vol. 128, Issue 3, 499-515, cover picture.

    Wemhöner K, Kanyshkova T, Silbernagel N, Fernandez-Orth J, Bittner S, Kiper AK, Rinné S, Netter MF, Meuth SG, Budde T & *Decher N. (2015). An N-terminal deletion variant of HCN1 in the epileptic WAG/Rij strain modulates HCN current densities. Front. Mol. Neurosci. 8: 63.*corresponding author

    Matschke LA, Bertoune M, Röper J, Snutch TP, Oertel WH, Rinné S & *Decher N. (2015). A concerted action of L- and T-type Ca2+ channels regulates locus coeruleus pacemaking. Mol. Cell. Neurosci.  68:293-302. *corresponding author 

    Rinné S, Kiper AK, Schlichthörl G, Dittmann S, Netter MF, Limberg SH, Silbernagel N, Zuzarte M, Moosdorf R, Wulf H, Schulze-Bahr E, Rolfes C & *Decher N. (2015). TASK-1 and TASK-3 may form heterodimers in human atrial cardiomyocytes. J. Mol. Cell. Cardiol. 81: 71-80. *corresponding author

    Wemhöner K, Friedrich C, Stallmeyer B, Coffey AJ, Grace A, Zumhagen S, Seebohm G, Ortiz-Bonnin B, Rinné S, Sachse FB, Schulze-Bahr E & *Decher N. (2015). Gain-of-function mutations in the calcium channel CACNA1C (Cav1.2) cause non-syndromic long-QT but not Timothy syndrome. J. Mol. Cell. Cardiol. 80: 186-195. *corresponding author

    Kiper AK, Rinné S, Rolfes C, Ramírez D, Seebohm G, Netter MF, González W & *Decher N. (2015). Kv1.5 blockers preferentially inhibit TASK-1 channels:  TASK-1 as a target against atrial fibrillation and obstructive sleep apnea? Pflügers Arch. 467: 1081-1090. *corresponding author

    *Decher N, Kiper AK,  Rolfes C, Schulze-Bahr E & Rinné S. (2015). The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias. Pflügers Arch. 467: 1055-1067. Invited Review. *corresponding author

    Tóth BI, Konrad M, Ghosh D, Mohr F, Halaszovich CR, Leitner MG, Vriens J, Oberwinkler J, Voets T (2015). Regulation of the transient receptor potential channel TRPM3 by phosphoinositides. J Gen Physiol 146(1):51-63

    Schneider FM, Mohr F, Behrendt M, Oberwinkler J (2015). Properties and functions of TRPM1 channels in the dendritic tips of retinal ON-bipolar cells. Eur J Cell Biol Jul-Sep; 94(7-9):420-7.

    Bouron A, Kiselyov K, Oberwinkler J (2015). Permeation, regulation and control of expression of TRP channels by trace metal ions. Pflügers Arch 467(6):1143-64. Review

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