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Publications

Chelladurai P, Dabral S, Basineni SR, Chen CN, Schmoranzer M, Bender N, Feld C, Nötzold RR, Dobreva G, Wilhelm J, Jungblut B, Zhao L, Bauer UM, Seeger W, Pullamsetti SS (2020). Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension. 
Scientific Reports 10: 12864.

Rakow S, Pullamsetti SS, Bauer UM, Bouchard C (2020). Assaying epigenome functions of PRMTs and their substrates. 
Methods 175, 53-65.
 
Chelladurai P, Boucherat O, Stenmark S, Kracht M, Seeger W, Bauer UM, Bonnet S, Pullamsetti SS. Targeting histone acetylation in PH and RV hypertrophy.
British Journal of Pharmacology, in press.

Bouchard C, Sahu P, Meixner M, Nötzold RR, Rust MB, Kremmer E, Feederle R, Hart-Smith G, Finkernagel F, Bartkuhn M, Savai Pullamsetti S, Nist A, Stiewe T, Philipsen S, Bauer UM (2018). Genomic location of PRMT6-dependent H3R2 methylation is linked to the transcriptional outcome of associated genes.
Cell Reports 24, 3339-52.

Frech M, Teichler S, Feld C, Bouchard C, Berberich H, Sorg K, Mernberger M, Bollinger L, Bauer UM, Neubauer A (2018). MYB induces the expression of the oncogenic corepressor SKI in acute myeloid leukemia.
Oncotarget 9, 22423-35.

Feld C, Sahu P, Frech M, Finkernagel F, Nist A, Stiewe T, Bauer UM#, Neubauer A#(2018). Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor of RUNX1.
Nucleic Acids Res. 46, 3412-28.

Berberich H, Terwesten F, Rakow S, Sahu P, Bouchard C, Meixner M, Philipsen S, Kolb P, Bauer UM (2017). Identification and in silico structural analysis of Gallus gallus protein arginine methyltransferase 4 (PRMT4).
FEBS Open Bio 7, 1909-1923.

Stein C, Nötzold RR, Riedl S, Bouchard C, Bauer, UM (2016). The Arginine Methyltransferase PRMT6 cooperates with Polycomb Proteins in regulating HOXA gene expression.
PLoS ONE 11, e0148892.

Bothur E, Raifer H, Haftmann C, Stittrich AB, Brüstle A, Brenner D, Bollig N, Bieringer M, Kang CK, Reinhard K, Camara B, Huber M, Visekruna A, Steinhoff U, Repenning A, Bauer UM, Sexl V, Radbruch A, Sparwasser T, Mashreghi MF, Mak TW, Lohoff M (2015). Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1.
Nature Communications 6, 8576.

Streubel G, Bouchard C, Berberich H, Zeller MS, Teichmann S, Adamkiewicz J, Müller R, Klempnauer K-H, Bauer, UM (2013). PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines.
PLoS Genetics 9, e1003343.

Stein C , Riedl S , Rüthnick D, Nötzold RR, Bauer UM (2012). The arginine methyltransferase PRMT6 regulates cell proliferation and senescence through transcriptional repression of tumor suppressor genes.
Nucleic Acids Res. 40, 9522-33.

Hauser AT, Bissinger EM, Metzger E, Repenning A, Bauer UM, Mai A, Schule R, Jung, M (2012). Screening assays for epigenetic targets using native histones as substrates.
J Biomol Screen 30, 17, 18-26.

Brand S, Teich R, Dicke T, Harb H, Yildirim AÖ, Tost J, Schneider-Stock R, Waterland RA, Bauer UM, von Mutius E, Garn H, Pfefferle PI, Renz H (2011). Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes.
J Allergy Clin Immunol. 128, 618-25.

van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S. (2010). Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.
Mol Cell Biol. 30, 260-72.

Kleinschmidt MA , Streubel G , Samans B, Krause M, Bauer UM (2008). The protein arginine methyltransferases CARM1 and PRMT1 cooperate in gene regulation.
Nucleic Acids Res. 36, 3202-13.

Hyllus D , Stein C , Schnabel K, Schiltz E, Imhof A, Dou Y, Hsieh J, Bauer UM (2007). PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation.
Genes Dev.21, 3369-80.

Wagner S., Weber S, Kleinschmidt MA, Nagata K, Bauer UM (2006). SET-mediated Promoter Hypoacetylation Is a Prerequisite for Coactivation of the Estrogen-responsive pS2 Gene by PRMT1.
J. Biol. Chem. 281, 27242-50.

Balint BL, Szanto A, Madi A, Bauer UM, Gabor P, Benko S, Puskás LG, Davies PJ, Nagy L (2005). Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells.
Mol Cell Biol. 25, 5648-63.

Komyod W, Bauer UM, Heinrich PC, Haan S, Behrmann I (2005). Are STATS arginine-methylated?
J Biol Chem. 280, 21700-5.

Daujat S , Bauer UM , Shah V, Turner B, Berger S, Kouzarides T (2002). Crosstalk between CARM1 methylation and CBP acetylation on histone H3.
Curr Biol. 12, 2090-7.

Langley E, Pearson M, Faretta M, Bauer UM, Frye RA, Minucci S, Pelicci PG, Kouzarides T (2002). Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence.
EMBO J. 21, 2383-96.

Bauer UM , Daujat S , Nielsen SJ, Nightingale K, Kouzarides T (2002). Methylation at arginine 17 of histone H3 is linked to gene activation.
EMBO Rep. 3, 39-44.

de Jager SM, Menges M, Bauer UM, Murra JA (2001). Arabidopsis E2F1 binds a sequence present in the promoter of S-phase-regulated gene AtCDC6 and is a member of a multigene family with differential activities.
Plant Mol Biol. 47, 555-68.

Nielsen SJ , Schneider R , Bauer UM, Bannister AJ, Morrison A, O'Carroll D, Firestein R, Cleary M, Jenuwein T, Herrera RE, Kouzarides, T (2001). Rb targets histone H3 methylation and HP1 to promoters.
Nature 412, 561-5.

Martinez-Balbas MA , Bauer UM , Nielsen SJ, Brehm A, Kouzarides T (2000). Regulation of E2F1 activity by acetylation..
EMBO J. 19, 662-71.

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