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Publications of subproject TP1

Human leukocyte antigen (HLA)-transgenic mice as a pre-clinical model of pemphigus vulgaris

Original papers

Hudemann C., Maglie R., Llamazares-Prada M., Beckert B., Didona D., Tikkanen R., Schmitt T., Hashimoto T., Waschke J., Hertl M., Eming R. Human Desmocollin 3‒Specific IgG Antibodies Are Pathogenic in a Humanized HLA Class II Transgenic Mouse Model of Pemphigus. J Invest Dermatol. 2022; 142(3B), 915-923. https://doi.org/10.1016/j.jid.2021.06.017.

Boch K, Dräger S, Zillikens D, Hudemann C, Hammers CM, et al. Immunization with desmoglein 3 induces non-pathogenic autoantibodies in mice. PLOS ONE. 2021. 16(11):e0259586. https://doi.org/10.1371/journal.pone.0259586

Sliwiak P, Folwarczny E, Didona D, Fink S, Wiegand C, Hanschmann E M, Hertl M, Hudemann C. Redox Enzymes of the Thioredoxin Family as Potential and Novel Markers in Pemphigus. Oxidative Medicine and Cellular Longevity. 2021. https://doi.org/10.1155/2021/6672693

Pollmann R, Walter E, Schmidt T, Waschke J, Hertl M, Möbs C, Eming R. Identification of Autoreactive B cell Subpopulations in Peripheral Blood of Autoimmune Patients with Pemphigus vulgaris. Front Immunol. 2019. https://doi.org/10.3389/fimmu.2019.01375

Walter E, Vielmuth F, Wanuske MT, Seifert M, Pollmann R, Eming R, Waschke J. Role of Dsg1- and Dsg3-Mediated Signaling in Pemphigus Autoantibody-Induced Loss of Keratinocyte Cohesion. Front Immunol. 2019. https://doi.org/10.3389/fimmu.2019.01128

Kugelmann D, Rötzer V, Walter E, Egu DT, Fuchs MT, Vielmuth F, Vargas-Robles H, Schnoor M, Hertl M, Eming R, Rottner K, Schmidt A, Spindler V, Waschke J. Role of Src and Cortactin in Pemphigus Skin Blistering. Front Immunol. 2019;10:626. https://doi.org/10.3389/fimmu.2019.00626

Review articles

Spindler V, Eming R, Schmidt E, Amagai M, Grando S, Jonkman MF, Kowalczyk AP, Müller EJ, Payne AS, Pincelli C, Sinha AA, Sprecher E, Zillikens D, Hertl M, Waschke J. Mechanisms Causing Loss of Keratinocyte Cohesion in Pemphigus. J Invest Dermatol. 2018; 138(1): 32-37. https://doi.org/10.1016/j.jid.2017.06.022

Pollmann R, Schmidt T, Eming R, Hertl M. Pemphigus: a Comprehensive Review on Pathogenesis, Clinical Presentation and Novel Therapeutic Approaches. Clin Rev Allergy Immunol. 2018;54(1):1-25

Garn, H., H. Renz. GATA-3-specific DNAzyme - A novel approach for stratified asthma therapy. Eur J Immunol 2017; 47: 22-30. https://doi.org/10.1002/eji.201646450

Potaczek. D.P., H. Garn, S.D. Unger, H. Renz. Antisense molecules: A new class of drugs. J Allergy Clin Immunol 2016; 137: 1334-1346. https://doi.org/10.1016/j.jaci.2015.12.1344