Die besten Publikationen der Grundlagenforschung 2010
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Institut für
Molekularbiologie und Tumorforschung (IMT) Stolz A, Ertych N, Kienitz A, Vogel C, Schneider V, Fritz, B, Jacob R, Dittmar G, Weichert W, Petersen I, Bastians, H (2010) The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells. Nat Cell Biol 12:492-499
Schlereth K, Beinoraviciute-Kellner R, Zeitlinger MK, Bretz AC, Sauer M, Charles JP, Vogiatzi F, Leich E, Samans B, Eilers M, Kisker C, Rosenwald A, Stiewe T (2010) DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell 38(3):356-368
Lauth M, Bergstrom A, Shimokawa T, Tostar U, Jin Q, Fendrich V, Guerra C, Barbacid M, Toftgard R (2010) DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS. Nat Struct Mol Biol 17:718-725
Herkert B, Dwertmann A, Herold S, Abed M, Naud JF, Finkernagel F, Harms GS, Orian A, Wanzel M, Eilers M (joint corresponding authors) (2010) The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis. J Cell Biol 188(6):905-918
Stielow B, Kruger I, Diezko R, Finkernagel F, Gillemans N, Kong-a-San J, Philipsen S, Suske G (2010) Epigenetic silencing of spermatocyte-specific and neuronal genes by SUMO modification of the transcription factor Sp3. PLoS Genet6, e1001203 |
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Institut für Medizinische Biometrie und Epidemiologie du Bois A, Herrstedt J,
Hardy-Bessard
Speliotes EK, Willer CJ, Berndt
SI,
Institut für Cytobiologie
und Cytopathologie Mühlenhoff U, Molik S, Godoy JR, Uzarska MA, Richter N, Seubert A, Zhang Y, Stubbe J, Pierrel F, Herrero E, Lillig CH, Lill R (2010) Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metab 12: 373-385
Netz DJA, Stümpfig M, Doré C, Mühlenhoff U, Pierik AJ, Lill R (2010) Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis. Nature Chem Biol 6:700-701
Sheftel AD, Stehling O, Pierik AJ, Elsässer HP, Mühlenhoff U, Webert H, Hobler A, Hannemann F, Bernhardt R, Lill R (2010) Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct functions in steroidogenesis, heme and Fe/S cluster biosynthesis. Proc Natl Acad Sci USA 107: 11775-11780 |
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Institut für Physiologische Chemie Krol J, Busskamp V, Markiewicz I, Stadler MB, Ribi S, Richter J, Duebel J, Bicker S, Fehling HJ, Schübeler D, Oertner TG, Schratt G, Bibel M, Roska B, Filipowicz W (2010) Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell 141(4): 618-31
Institut für Physiologie und
Pathophysiologie Decher N, Streit AK, Rapedius M, Netter MF, Marzian S, Ehling P, Schlichthörl G, Craan T, Renigunta V, Köhler A, Dodel RC, Navarro-Polanco RA, Preisig-Müller R, Klebe G, Budde T, Baukrowitz T, Daut J (2010) RNA editing modulates the binding of drugs and highly unsaturated fatty acids to the open pore of Kv potassium channels. EMBO J 29(13):2101-13 |
Institut für Medizinische Mikrobiologie und Krankenhaushygiene Staudt V*, Bothur E*, Klein M, Lignau K, Reuter S, Grebe N, Gerlitzki B, Hoffmann M, Ulges A, Taube C, Dehzad N, Becker M, Stassen M, Steinborg A, Lohoff M, Schild H, Schmitt E, Bopp T, *geteilte Erstautorenschaft (2010) Interferon-Regulatory-Factor 4 is essentially involved in the developmental program of T helper 9 cells. Immunity 33:192-202
Institut für Virologie Welsch, S., Kolesnikova, L., Krahling, V., Riches, J.D., Becker, S* and Briggs, J.A. - *geteilte Seniorautorschaft (2010) Electron tomography reveals the steps in filovirus budding. PLoS Pathog 6, e1000875 |
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Originalarbeit, Erst- oder Letztautor und Journal Impact Faktor > 7,5 oder
Originalarbeit, Mitautorenschaft und Journal Impact Faktor > 14


