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Die besten Publikationen der Grundlagenforschung 2014

 

Institut für Anatomie und Zellbiologie

Rossmann A, Mandic R, Heinis J, Hoeffken H, Kuessner O, Kinscherf R, Weihe E, Bette M (2014) Intraperitoneal oxidative stress in rabbits with papillomavirus-associated head and neck cancer induces tumoricidal immune response that is adoptively transferable. Clin Cancer Res 20(16):4289-301

 

Institut für Molekularbiologie und Tumorforschung (IMT)

Preussner M, Wilhelmi I, Schultz AS, Finkernagel F, Michel M, Moroy T, Heyd F (2014) Rhythmic U2af26 alternative splicing controls PERIOD1 stability and the circadian clock in mice. Mol Cell 54: 651-62

Stielow C, Stielow B, Finkernagel F, Scharfe M, Jarek M, Suske G (2014) SUMOylation of the polycomb group protein L3MBTL2 facilitates repression of its target genes. Nucleic Acids Res 42(5): 3044-58

 

Charles JP, Fuchs J, Hefter M, Vischedyk JB, Kleint M, Vogiatzi F, Schäfer JA, Nist A, Timofeev O, Wanzel M, Stiewe T (2014) Monitoring the dynamics of clonal tumour evolution in vivo using secreted luciferases. Nat Commun 5, 3981

 

Institut für Physiologische Chemie

Fiore R, Rajman M, Schwale C, Bicker S, Antoniou A, Bruehl C, Draguhn A, Schratt G (2014) MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression. EMBO J 33(19):2231-46

 

Institut für Physiologie und Pathophysiologie

Friedrich C, Rinné S, Zumhagen S, Kiper AK, Silbernagel N, Netter MF, Stallmeyer B, Schulze-Bahr E, Decher N (2014) Gain-of-function mutation in TASK-4 channels and severe cardiac conduction disorder. EMBO Mol Med 6(7):937-51

Gorbunov D, Sturlese M, Nies F, Kluge M, Bellanda M, Battistutta R, Oliver D (2014) Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters. Nat Commun 5:3622

Wilke BU, Linder M, Greifenberg L, Albus A, Kronimus Y, Bünemann M, Leitner MG, Oliver D (2014) Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors. Nat Commun 5:5540

 

 Institut für Medizinische Biometrie und Epidemiologie

Jarick I, Volckmar A-L, Pütter C, Pechlivanis S, Nguyen TT, Dauvermann MR, Beck S, Albayrak Ö, Scherag S, Gilsbach S, Cichon S, Hoffmann P, Degenhardt F, Nöthen MM, Schreiber S, Wichmann HE, Jöckel KH, Heinrich J, Tiesler CMT, Faraone SV, Walitza S, Sinzig J, Freitag C, Meyer J, Herpertz-Dahlmann B, Lehmkuhl G, Renner TJ, Warnke A, Romanos M, Lesch KP, Reif A, Schimmelmann BG, Hebebrand J, Scherag A, Hinney A (2014) Genome-wide analysis of rare copy number variations reveals PARK2 as a candidate gene for attention-deficit/hyperactivity disorder. Mol Psychiatry 19: 115-21

Herpertz-Dahlmann B, Schwarte R, Krei M, Egberts K, Warnke A, Wewetzer C, Pfeiffer E, Fleischhaker C, Scherag A, Holtkamp K, Hagenah U, Bühren K, Konrad K, Schmidt U, Schade-Brittinger C, Timmesfeld N, Dempfle A (2014) Day-patient treatment after short inpatient care versus continued inpatient treatment in adolescents with anorexia nervosa (ANDI): a multicentre, randomised, open-label, non-inferiority trial. The Lancet 383: 1222-29

 

Institut für Medizinische Soziologie und Sozialmedizin

Wang H, Liddel CA, Coates MM, …., Westerman R, …, Zhu S, Lopez AD, Murray CJ (2014) Global, regional, and national levels of neonatal, infant, and under-5 mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet 384(9947): 957-79

Kassebaum NJ, Bertozzi-Villa A, Coggeshall MS, … Westerman R, …, Naghavi M, Murray CJ, Lozano R (2014) Global, regional, and national levels and causes of maternal mortality during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet 384(9947): 980-1004

Murray CJ, Ortblad KE, Guinovart C, …, Westerman R,…, Zou XN, Lopez AD, Vos T (2014) Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet 384(9947): 1005-70

Ng M, Fleming T, Robinson M, …, Werdecker A, …, Lopez AD, Murray CJ, Gakidou E (2014) Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013. The Lancet 384(9945): 766-81

                  

Pharmakologisches Institut

Purvanov V, Holst M, Khan J, Baarlink C, Grosse R (2014) G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion. Elife  Jun 20;3:e02786

Worzfeld T, Swiercz JM, Sentürk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S (2014) Genetic dissection of plexin signaling in viso. Proc Natl Acad Sci USA 111:2194-99

 

Institut für  Klinische Zytobiologie und Zytopathologie

Walter KM, Schönenberger MJ, Trötzmüller M, Horn M, Elsässer HP, Moser AB, Lucas MS, Schwarz T, Gerber PA, Faust PL, Moch H, Köfeler HC, Krek W, Kovacs WJ (2014) Hif-2α promotes degradation of Mammalian peroxisomes by selective autophagy. Cell Metab 20(5):882-97

Webert H, Freibert S-A, Gallo A, Heidenreich T, Linne U, Amlacher S, Hurt E, Mühlenhoff U, Banci L, Lill R (2014) Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin. Nat Commun 5, 5013

Srinivasan V, Pierik AJ, Lill R (2014) Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1. Science 343: 1137-1140

 

Institut für Virologie

Linster M, van Boheemen S, de Graaf M, Schrauwen EJ, Lexmond P, Manz B, Bestebroer TM, Baumann J, van Riel D, Rimmelzwaan GF, Osterhaus AD, Matrosovich M, Fouchier RA, Herfst S (2014) Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus. Cell 157:329-39

Wolf T, Kann G, Becker S, Stephan C, Brodt HR, de Leuw P, Grunewald T, Vogl T, Kempf VA, Keppler OT, Zacharowski K (2014) Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care. The Lancet 385, 9976:1428-35

Dolnik O, Kolesnikova L, Welsch S, Strecker T, Schudt G, Becker S (2014) Interaction with Tsg101 is necessary for the efficient transport and release of nucleocapsids in marburg virus-infected cells. PLoS pathogens 10, e1004463

 

 

Institut für Humangenetik

Pastore F, Dufour A, Benthaus T, Metzeler KH, Maharry KS, Schneider S, Ksienzyk B, Mellert G, Zellmeier E, Kakadia PM, Unterhalt M, Feuring-Buske M, Buske C, Braess J, Sauerland MC, Heinecke A, Krug U, Berdel WE, Buechner T, Woermann B, Hiddemann W, Bohlander SK, Marcucci G, Spiekermann K, Bloomfield CD, Hoster E (2014) Combined molecular and clinical prognostic index for relapse and survival in cytogenetically normal acute myeloid leukemia. J Clin Oncology 32 (15): 1586-94

Malik S, Percin FE, Bornholdt D, Albrecht B, Percesepe A, Koch MC, Landi A, Fritz B, Khan R, Mumtaz S, Akarsu NA, Grzeschik KH (2014) Mutations Affecting the BHLHA9 DNABinding Domain Cause MSSD, Mesoaxial synostotic Syndactyly with Phalangeal Reduction, Malik-Percin Type. Am J Hum Genetics 95(6): 649-59

 

 

 

 

 

 

 

 



Auswahlkriterien:
Originalarbeit, Erst- oder Letztautor und Journal Impact Faktor > 7,5 oder
Originalarbeit, Mitautorenschaft und Journal Impact Faktor > 14

Zuletzt aktualisiert: 28.05.2015 · Gerd Rinke

 
 
 
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