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Die besten Publikationen der Grundlagenforschung 2011

 

Institut für Molekularbiologie und Tumorforschung (IMT)

Kress TR, Cannell IG, Brenkman AB, Samans B, Gaestel M, Roepman P, Burgering BM, Bushell M, Rosenwald A, Eilers M (2011): The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis. Mol Cell 41: 445-457

 

Murawska M, Hassler M, Renkawitz-Pohl R, Ladurner A, Brehm A (2011): Stress-induced PARP activation mediates recruitment of Drosophila Mi-2 to promote heat shock gene expression. PLoS Genet 7: e1002206

 

Stockert J, Adhikary T, Kaddatz K, Finkernagel F, Meissner W, Müller-Brüsselbach S, Müller R (2011): Reverse crosstalk of TGF{β} and PPAR{β}/{δ} signaling identified by transcriptional profiling. Nucleic Acids Res 39: 119-131

 

Teichler S, Illmer T, Roemhild J, Ovcharenko D, Stiewe T, Neubauer A (2011): MicroRNA29a regulates the  expression of the nuclear oncogene Ski. Blood 118: 1899-19

 

Institut für Physiologie und Pathophysiologie

Vriens J, Owsianik G, Hofmann T, Philipp SE, Stab J, Chen X, Benoit M, Xue F, Janssens A, Kerselaers S, Oberwinkler J, Vennekens R, Gudermann T, Nilius B, Voets T (2011): TRPM3 is a nociceptor channel involved in the detection of noxious heat. Neuron 70: 482-494

 

Schaechinger TJ, Gorbunov D, Halaszovich CR, Moser T, Kuegler S, Fakler B, Oliver D (2011): A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity. EMBO J 30: 2793-2804

 

Institut für Medizinische Biometrie und Epidemiologie

Jarick I, Vogel CIG, Scherag S, Schäfer H, Hebebrand J, Hinney A, Scherag A (2011): Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis. Human Molecular Genetics 20 (4): 840-852

 

Pharmakologisches Institut

Ibrahim AF, Weirauch U, Thomas M, Grünweller A, Hartmann RK, Aigner A (2011): MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma. Cancer Res 71 (15):5214-24

       

Institut für  Klinische Zytobiologie und Zytopathologie

Hoffmann B, Uzarska MA, Berndt C, Godoy JR, Haunhorst P, Lillig CH, Lill R, Mühlenhoff U (2011): The multidomain thioredoxin-monothiol glutaredoxins represent a distinct functional group. Antioxid Redox Signal 15: 19-30


Navarro-Sastre A, Tort F, Stehling O, Uzarska MA, Arranz JA, del Toro M, Labayru MT, Landa J, Font A, Garcia-Villoria J, Merinero B, Ugarte M, Gutierrez-Solana LG, Campistol J, Garcia-Cazorla A, Vaquerizo J, Riudor E, Briones P, Elpeleg O, Ribes A, Lill R (2011): A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins. Am J Hum Genet 89: 656-667

 

Institut für Virologie

Pichlmair A, Lassnig C, Eberle CA, Gorna MW, Baumann CL, Burkard TR, Burckstummer T, Stefanovic A, Krieger S, Bennett KL, Rulicke T, Weber F, Colinge J, Müller M, Superti-Furga G (2011): IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA. Nat Immunol 12: 624-30

 

Institut für Humangenetik

Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, Metzeler KH, Poeppl A, Ling V, Beyene J, Canty AJ, Danska JS, Bohlander SK, Buske C, Minden MD, Golub TR, Jurisica I, Ebert BL, Dick JE (2011): Stem cell gene expression programs influence clinical outcome in human leukemia. Nat. Med. 17: 1086-1093

 

Greif PA, Yaghmaie M, Konstandin NP, Ksienzyk B, Alimoghaddam K, Ghavamzadeh A, Hauser A, Graf A, Krebs S, Blum H, Bohlander SK (2011): Somatic mutations in acute promyelocytic leukemia (APL) identified by exome sequencing. Leukemia 25: 1519-1522

 

Herold T, Jurinovic JV, Metzeler KH, Boulesteix AL, Bergmann M, Seiler T, Mulaw M, Thoene S, Dufour A, Pasalic Z, Schmidberger M, Schmidt M, Schneider S, Kakadia PM, Feuring-Buske M, Braess J, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Bohlander SK (2011): An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia. Leukemia 25: 1639-1645

 

Kakadia PM, Tizazu B, Mellert G, Harbott J, Röttgers S, Quentmeier H, Spiekermann K, Bohlander SK (2011): A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL). Leukemia 25: 1645-1649

 

Konstandin N, Bultmann S, Szwagierczak A, Dufour A, Ksienzyk B, Schneider F, Mulaw M, Kakadia PM, Schneider S, Spiekermann K, Leonhardt H, Bohlander SK (2011): Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia. Leukemia 25:1649-1652




Auswahlkriterien:
Originalarbeit, Erst- oder Letztautor und Journal Impact Faktor > 7,5 oder
Originalarbeit, Mitautorenschaft und Journal Impact Faktor > 14

Zuletzt aktualisiert: 03.07.2012 · Gerd Rinke

 
 
 
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