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News and Highlights from the Meggers Laboratory

Newest Publications

Peng's asymmetric photoelectrocatalysis published as Synfacts.

Xin's oxyamination published as Synfacts.

Dominik's stereogenic-at-iron publication in EurJIC becomes Reader's Choice!

Xin's nitrene-mediated oxyamination published in Angewandte Chemie: Angew. Chem. Int. Ed. 2023, DOI: 10.1002/anie.202314398.

Peng's work on asymmetric photoelectrocatalysis published in Nature Catalysis: Nat. Catal. 2023, DOI: 10.1038/s41929-023-01050-y.

Our JACS 2021 paper (10.1021/jacs.1c06637) on photoderacemization of ketones is one of the most cited JACS publications from 2020-2021!

Account on chiral-at-Ru nitrene-mediated asymmetric C-H functionalizations: Acc. Chem. Res. 2023, 56, 1128-1141.

Review on the role of metal stereogenicity in asymmetric transition metal catalysis: Chem. Rev. 2023, 123, 4764-4794.

The most economic synthesis of amino acids: Just one step starting from carboxylic acids! Nat. Synth. 2023, 2, 645-652.

Nemrud's publication on chiral-at-iron catalyst design was selected for the coverpicture (Organometallics 2022, Vol. 41, Issue 24)!

Using transition metal nitrenes for enantioselective C-H-oxygenation: Angew. Chem. Int. Ed. 2022, 61, e202211971.

Synform Article by Prof. Matteo Zanda highlighting our invented amino acid synthesis by stereocontrolled 1,3-nitrogen migration.

Amino acid synthesis made easy by novel stereocontrolled 1,3-nitrogen migration: Nat. Chem. 2022, 14, 566-573. See also "Behind the Paper".

Catalytic asymmetric electrosynthesis: J. Am. Chem. Soc. 2022, 144, 6964.

Enantioselective ring-closing C(sp3)-H amination with sulfamoyl azides highlighted in Organic Chemistry Portal: Click here.

First catalytic photoderacemization of ketones: J. Am. Chem. Soc. 2021, 143, 13393.

Design of a new chiral iron catalyst: ACS Catal. 2021, 11, 7467.

Our work on asymmetric ring-closing aminooxygenation of alkenes (Org. Lett. 2020, 22, 6653) is highlighted by Douglass F. Taber: Org. Chem. Highlights 2021, July 26.

Highly efficient amination of unactivated C-H bonds with a simple iron catalyst: Angew. Chem. Int. Ed. 2021, 60, 6314-6319. This work has been highlighted in Synfacts: Synfacts 2021, 17, 0377.

Our nitrene-mediated C-H oxygenation highlighted in Synfacts: Synfacts 2020, 16, 1430.

A novel reaction: C-H oxygenation via nitrene chemistry! Angew. Chem. Int. Ed. 2020, 59, 21706-21710.

TOC graphic: Yuqi Tan

Enantioselective C(sp3)-H amination of urea derivatives:Chem 2020, 6, 2024. See also highlight by Bas de Bruin.

TOC graphic: Zijun Zhou

Atroposelective synthesis with chiral-at-Rh catalyst: Angew. Chem. Int. Ed. 2020, 59, 13552.

TOC graphic: Chen-Xi Ye

Teaching an old dog new tricks. Complementing Ru-Pybox with cyclometalated NHC ligand for enantioselective nitrene chemistry: Angew. Chem. Int. Ed. 2020, 59, 12392.

TOC graphic: Eric Meggers

News & Highlights

May 2023: Our publication on Enantioselective and enantioconvergent Fe-catalyzed C(sp3)-H amination to access chiral 2-imidazolidinones (Chin. J. Chem. 2023, 41, 2065-2070) receives the NHU-CJC award!

October 2022: Summary of Chiral-at-Metal Catalysis by our group. Nemrud's and Dominik's prize-winning poster for "Fachbereichstag" 2022. PDF file.

September 2022: European Patent Application on the catalytic asymmetric synthesis of amino acids from carboxylic acids in a single step.

March 2022: European Patent Application on the catalytic asymmetric synthesis of amino acids by 1,3-nitrogen migration.

Oct. 2021: Eric Meggers joins Chinese Journal of Chemistry (CJC) as an Associate Editor.

ERC Advanced Grant on the development of earth-abundant chiral-at-metal catalysts starting in 2021!

How did we get from enzyme inhibitor design to asymmetric catalysis? Read this Essay: Angew. Chem. Int. Ed. 2017, 56, 5668.

Previous LOEWE Research Cluster "SynChemBio": Link to ProLOEWE

Nature Catalysis publication on asymmetric electrochemistry: Nat. Catal. 2019, 2, 34-40. See also "Behind the Paper".

Nature publication on asymmetric photocatalysis: Nature 2014, 515, 100-103. See also News & Views Feature by Skubi and Yoon.


Introduction to chiral-at-metal catalyst design in the Meggers group: Click here for Youtube video.