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Lennart Randau

Portrait Lennart Randau
Photo: Rolf K. Wegst

Our research group “Prokaryotic RNA biology” investigates RNA-processing mechanisms and RNA-binding proteins in different environmentally relevant bacteria and archaea with a special focus on the characterization of RNA modifications and the investigation of non-canonical CRISPR-Cas systems. Within the the M4C consortium we want to understand the role of non-canonical CRISPR-Cas systems in stress response and program new regulatory circuits based on CRISPR-Cas technologies.

Research Focus:

Microbes as Responders; Microbes providing Solutions

Key Publication(s):

Guo X, Sanchez-Londono M, Gomes-Filho JV, Hernández-Tamayo R, Rust S, Immel­man L, Schäfer P, Wiegel J, Graumann P, *Randau L. Characterization of the self-targeting Type IV CRISPR interference system in Pseudomonas oleo­vorans. Nature Microbiology 2022 7:1870-1878. doi: 10.1038/s41564-022-01229-2

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