Epithelial Homeostasis and Pathogenesis - Dr. Rust

How do cells coordinate proliferation, differentiation and morphogenetic movements in time and space? How is a functional tissue build starting from a single stem cell? And what happens if homeostasis is deregulated?

We use Drosophila to investigate mechanisms of epithelial homeostasis with single-cell transcriptomics and high-resolution live imaging approaches. Select a topic to learn more about our ongoing research projects.