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Originalarbeiten und Reviews 2021

Originalarbeiten 2021:

1. Dental Biofilm and Saliva Microbiome and Its Interplay with Pediatric Allergies
   Arweiler NB, Rahmel V, Alhamwe BA, Alhamdan F, Zemlin M, Boutin S, Dalpke A, Renz H.
   Microorganisms. 9(6):1330. 10.3390/microorganisms9061330, 2021
   doi: 10.3390/microorganisms90613302021
   (IF 4.1)
2. Homologies between SARS-CoV-2 and allergen proteins may direct T cell-mediated heterologous immune responses
   Balz K, Kaushik A, Chen M, Cemic F, Heger V, Renz H, Nadeau K, Skevaki C.
   Sci Rep. 26;11(1):4792, 2021
   doi: 10.1038/s41598-021-84320-8    
   (IF 4.4)
3. New-onset IgG autoantibodies in hospitalized patients with COVID-19
   Chang SE, Feng A, Meng W, Apostolidis SA, Mack E, Artandi M, Barman L, Bennett K, Chakraborty S, Chang I, Cheung P, Chinthrajah S, Dhingra S, Do E, Finck A, Gaano A, Geßner R, Giannini HM, Gonzalez J, Greib S, Gündisch M, Hsu AR, Kuo A, Manohar M, Mao R, Neeli I, Neubauer A, Oniyide O, Powell AE, Puri R, Renz H, Schapiro JM, Weidenbacher PA, Wittman R, Ahuja N, Chung HR, Jagannathan P, James J, Kim PS, Meyer NJ, Nadeau K, Radic M, Robinson WH, Singh U, Wang TT, Wherry EJ, Skevaki C, Prak ETL, Utz PJ.
   Nat. Comm., 12(1):5417 2021
   doi: 10.1101/2021.01.27.21250559
4. Rapamycin delays allograft rejection in obese graft recipients through induction of myeloid-derived suppressor cells.
   Deißler A, Della Penna A, van Geffen C, Gonzalez-Menendez I, Quintanilla-Martinez L, Günther A, Schneiderhan-Marra N, Hartl D, Nürnberg B, Königsrainer A, Kolahian S, Quante M.
   Immunol Lett. 236:1-11, 2021
   doi: 10.1016/j.imlet.2021.05.003   
   (IF 4.230)
5. Caspase-cleaved keratin 18 measurements identified ongoing liver injury after bariatric surgery
   Hempel F, Roderfeld M, Müntnich LJ, Albrecht J, Oruc Z, Arneth B, Karrasch T, Pons-Kühnemann J, Padberg W, Renz H, Schäffler A, Roeb E.
   J Clin Med 10: 1233-45, 2021
   doi: 10.3390/jcm1061233
   (IF 3.37)
6. Joint ESCMID, FEMS, IDSA, ISID and SSI position paper on the fair handling of career breaks among physicians and scientists when assessing eligibility for early-career awards
   Huttner A, Bricheux A, Buurmeijer-van Dijk CJM, Harvey M, Holmes A, Lassmann B, Lavergne V, Mailles A, Mendelson M, Muller N, Sanguinetti M, Sears C, Skevaki C, Syed U, Thomas S, Swartz TH.
   European Society of Clinical Microbiology and Infectious Diseases; Federation of European Microbiological Societies; Infectious Disease Society of America; International Society for Infectious Diseases; Swiss Society for Infectious Diseases.
   Clin Microbiol Infect., 18:S1198-743X(21)00056-2, 2021
   doi:10.1016/j.cmi.2021.01.029
   (IF 8.0)
7. Microbial diversity in homes and the risk of allergic rhinitis and inhalant atopy in two European birth cohorts
   Hyytiäinen H, Kirjavainen PV, Täubel M, Tuoresmäki P, Casas L, Heinrich J, Herberth G, Strandl M, Renz H, Piippo-Savolainen E, Hyvärinen A, Pekkanen J, Karvonen AM
   Environ Res., 110835, 2021
   doi: 10.1016/j.envres.2021.110835
   (IF 5.7)
8. Protocol for an observational study to identify potential predictors of an acute exacerbation in patients with chronic obstructive pulmonary disease (the PACE Study)
   Kenn K, Gloeckl R, Leitl D, Schneeberger T, Jarosch I, Hitzl W, Alter P, Sczepanski B, Winterkamp S, Boensch M, Schade-Brittinger C, Skevaki C, Holz O, Jones PW, Vogelmeier CF, Koczulla AR
   BMJ Open.11(2):e043014, 2021
   doi: 10.1136/bmjopen-2020-043014 
   (IF 39.9)
9. Fetomaternal immune cross talk modifies T-cell priming through sustained changes to DC function
   Lacorcia M, Bhattacharjee S, Laubhahn K, Alhamdan F, Ram M, Muschaweckh A, Potaczek DP, Kosinska A, Garn H, Protzer U, Renz H, Prazeres da Costa C
   J Allergy Clin Immunol, 2021
   doi: 10.1016/j.jaci.2021.02.031
   (IF 10.8)
10. Relationship between maternal bone biomarkers and fetal adiposity through normal pregnancy
    Mastorakos G, Maliopoulos D, Kasioni S, Bargiota A, Barber TM, Skevaki C, Papassotiriou I, Vrachnis N, Farmakides G, Vlahos NF, Kumar S, Valsamakis G
    J Clin Endocrinol Metab.106(7):e2647-e2655, 2021
    doi: 10.1210/clinem/dgab152
    (IF 6.0)
11. The janus-kinase inhibitor ruxolitinib in SARS-CoV-2 induced acute respiratory distress syndrome (ARDS)
    Neubauer A, Johow J, Mack E, Burchert A, Meyn D, Kadlubiec A, Torje I, Wulf H, Vogelmeier CF, Hoyer J, Skevaki C, Muellenbach RM, Keller C, Schade-Brittinger C, Rolfes C, Wiesmann T.
    Leukemia. 12:1-7, 2021
    doi: 10.1038/s41375-021-01374-3
    (IF 11.5)
12. Validation study of a new chemiluminescent singleplex IgE assay in a set of Italian allergic rhinitis patients
    Potapova E, Bauersachs D, Villella V, Meneguzzi G, Scala E, Sfika I, Tripodi S, Panetta V, Dramburg S, Skevaki C, Matricardi PM
    Clin Exp Allergy. 51(4):604-613, 2021
    doi: 10.1111/cea.13785
    (IF 5.0)
13. Deep phenotypical characterization of human CD3+ CD56+ T cells by mass cytometry
    Romero-Olmedo AJ, Schulz AR, Huber M, Brehm CU, Chang HD, Chiarolla CM, Bopp T, Skevaki C, Berberich-Siebelt F, Radbruch A, Mei HE, Lohoff M
    Eur J Immunol. 51(3):672-681, 2021
    doi: 10.1002/eji.202048941
    (IF 5.5)
14. Allergen extract- and component-based diagnostics in children of the ALLIANCE asthma cohort
    Skevaki C, Tafo P, Eiringhaus K, Timmesfeld N, Weckmann M, Happle C, Nelson PP, Maison N, Schaub B, Ricklefs I, Fuchs O, von Mutius E, Kopp MV, Renz H, Hansen G, Dittrich AM ALLIANCE Study Group
    Clin Exp Allergy, 2021
    doi: 10.1111/cea.13964
    (IF 5.0)
15. In vitro effects of 5-lipoxygenase pathway inhibition on rhinovirus-associated bronchial epithelial inflammation
    Spyridaki I, Taka S, Skevaki C, Trochoutsou A, Papadopoulos NG
    Pulm Ther. 7(1):237-249, 2021
    doi: 10.1007/s41030-021-00152-x
16. Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4
    van Geffen C, Deißler A, Beer-Hammer S, Nürnberg B, Handgretinger R, Renz H, Hartl D, Kolahian S
    Front Immunol. 12:695933, 2021
    doi: 10.3389/fimmu.2021.69593
    (IF 8.786 )
17. Constitutive immune activity promotes JNK- and FoxO-dependent remodeling of Drosophila airways
    Wagner C, Uliczka K, Bossen J, Niu X, Fink C, Thiedmann M, Knop M, Vock C, Abdelsadik A, Zissler UM, Isermann K, Garn H, Pieper M, Wegmann M, Koczulla AR, Vogelmeier CF, Schmidt-Weber CB, Fehrenbach H, König P, Silverman N, Renz H, Pfefferle P, Heine H, Roeder T
    Cell Rep. 6;35(1):108956, 2021
    doi: 10.1016/j.celrep.2021.108956
    (IF 8.1)
18. Characteristics of Three Different Chemiluminescence Assays for Testing for SARS-CoV-2 Antibodies
    Weber MC, Risch M, Thiel SL, Grossmann K, Nigg S, Wohlwend N, Lung T, Hillmann D, Ritzler M, Ferrara F, Bigler S, Egli K, Bodmer T, Imperiali M, Salimi Y, Fleisch F, Cusini A, Heer S, Renz H, Paprotny M, Kohler P, Vernazza P, Risch L, Kahlert CR
    Dis Markers, 8810196, 2021
    doi: 10.1155/2021/8810196
    (IF 2.7)
19. Plasma protein biomarkers for early detection of pancreatic ductal adenocarcinoma
    Yu J, Ploner A, Kordes M, Löhr M, Nilsson M, de Maturana MEL, Estudillo L, Renz H, Carrato A, Molero X, Real FX, Malats N, Ye W
    Int J Cancer, 148(8):2048-2058, 2021
    doi: 10.1002/ijc.33464
    (IF 5.1)
20. IL-1β augments TGF-β inducing epithelial-mesenchymal transition of epithelial cells and associates with poor pulmonary function improvement in neutrophilic asthmatics
    Zhang S, Fan Y, Lu Q, Fang X, Zhang C, Yue J, Bai W, Wang G, Chen Z, Skevaki C, Renz H, Liu X, Xie M
    Respir Res. 22(1):21, 2021
    doi: 10.1186/s12931-021-01808-7
    (IF 5.6)
21. The mRNA m6A reader YTHDF2 supresses pro-inflammatory pathways and sustains hematopoietic stem cell function
    Mapperly C, van de Lagemaat L, Tavosanis A, Paris J, Lawson H, Campos J, Sarapuu A, Choe J, Ivanova I, Krause DS, Von Kriegsheim A, A, Much C, Morgan M, Gregory RI, Mead AJ, O'Carroll D, Kranc KR
    J Exp Med. 2021 ; 218:e20200829, 2021
    doi : 10.1084/jem.20200829
    (IF 14.3)
22. Germline variants drive myelodysplastic syndrome and aplastic anemia in young adults
    Feuerstein S, Churpek J, Walsh T, Keel S, Hakkarainen M, Schroeder T, Germin U, Geyh S, Heuser M, Thol F, Pohlkamp C, Haferlach T, Gao J, Owen C, Goehring G, Schlegelberger B, Verma D, Krause DS, Gao G, Cronin T, Gulsuner S, Lee M, Pritchard CC, Subramanian HP, Del Gaudio D, Li Z, Das S, Kilpivaara O, Wartiovaara-Kautto U, Wang ES, Griffiths EA, Döhner K, Döhner H, King MC, Godley LA
    Leukemia, 35(8) :2439-2444, 2021
    doi : 10.1038/s41375-021-01137-0
    (IF 11.5)
23. The endolysosomal adaptor PLEKHM1 is a direct target for both mROR and MAPK pathways
    Gubas A, Karantanou C, Popovic D, Tascher G, Hoffmann ME, Dawe N, Dikic I, Krause DS, McEwan DG
    FEBS Lett, 595(7):864-880, 2021
    doi : 10.1002/1873-3468.14041
    (IF 4.1)
24. The age of the bone marrow microenvironment influences B-cell acute lymphoblastic leukemia progression via CXCR5-CXCL3
    Zanetti C, Kumar R, Ender J, Godavarthy PS, Harmann M, Hey J, Breuer K, Weissenberger ES, Minciacchi V, Karantanou C, Gu Z, Roberts KG, Metzler M, Stock W, Mullighan CG, Bloomfield CD, Filmann N, Bankov K, Hartmann S, Hasserjian RP, Cousins A, Halsey C, Plass C, Lipka DB, Krause DS
    Blood, 138(19) :1870-1884, 2021
    doi : 10.1182/blood.2021011557
    (IF 23.6)
    
    

Übersichtsarbeiten und Editorials 2021:

1. The impact of microRNAs on myeloid-derived suppressor cells in cancer
   Baghbani E, Noorolyai S, Duijf PHG, Silvestris N, Kolahian S, Hashemzadeh S, Baghbanzadeh Kojabad A, FallahVazirabad A, Baradaran B
   Hum Immunol. 82:668-678, 2021
   doi: 10.1016/j.humimm.2021.04.009
   (IF 2.211)
2. T Cell Repertoire During Ontogeny and Characteristics in Inflammatory Disorders in Adults and Childhood
   Foth S, Völkel S, Bauersachs D, Zemlin M, Skevaki C
   Front Immunol. 9;11:611573, 2021
   doi: 10.3389/fimmu.2020.611573
   (IF 7.6)
3. Corrigendum to "Review of trials currently testing treatment and prevention of COVID-19"
   Fragkou PC, Belhadi D, Peiffer-Smadja N, Moschopoulos CD, Lescure FX, Janocha H, Karofylakis E, Yazdanpanah Y, Mentré F, Skevaki C, Laouénan C, Tsiodras S; ESCMID Study Group for Respiratory Viruses
   Clin Microbiol Infect. 27(3):499, 2021
   doi: 10.1016/j.cmi.2021.01.024
   (IF 8.0)
4. Impact of early life nutrition on children's immune system and noncommunicable diseases through its effects on the bacterial microbiome, virome and mycobiome
   Fragkou PC, Karaviti D, Zemlin M, Skevaki C
   Front Immunol. 12:644269, 2021
   doi: 10.3389/fimmu.2021.644269
   (IF 7.6)
5. Biologics for atopic diseases : Indication, side effect management and new developments
   Jappe U, Beckert H, Bergmann KC, Gülsen A, Klimek L, Philipp S, Pickert J, Rauber-Ellinghaus MM, Renz H, Taube C, Treudler R, Wagenmann M, Werfel T, Worm M, Zubertier T
   Allergol Select : 5 :1-25, 2021
   doi : 10.5414/ALX02197E
   (IF 5.8)
6. Deciphering the complex interplay between pancreatic cancer, diabetes mellitus subtypes and obesity/BMI through causal inference and mediation analyses
   Molina-Montes E, Coscia C, Gómez-Rubio P, Fernández A, Boenink R, Rava M, Márquez M, Molero X, Löhr M, Sharp L, Michalski CW, Farré A, Perea J, O'Rorke M, Greenhalf W, Iglesias M, Tardón A, Gress TM, Barberá VM, Crnogorac-Jurcevic T, Muñoz-Bellvís L, Dominguez-Muñoz JE, Renz H, Balcells J, Costello E, Ilzarbe L, Kleeff J, Kong B, Mora J, O'Driscoll D, Poves I, Scarpa A, Yu J, Hidalgo M, Lawlor RT, Ye W, Carrato A, Real FX, Malats N; PanGenEU Study Investigators
   Gut gutjnl-2019-319990, 2021
   doi: 10.1136/gutjnl-2019-319990
   (IF 19.8)
7. How to interpret and use COVID-19 serology and immunology tests
   Ong DSY, Fragkou PC, Schweitzer VA, Chemaly RF, Moschopoulos CD, Skevaki C. European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Respiratory Viruses (ESGREV)
   Clin Microbiol Infect, 981-986, 2021
   doi: 10.1016/j.cmi.2021.05.001
   (IF 8.0)
8. Bewertung von SARS-CoV-2 Antigen-Schnelltesten. Assessment of SARS-CoV-2 rapid antigen tests
   Özçürümez MK, Katsonunas S, Holdenrieder S, von Meyer A,  Renz H, Wölfel R
   J Lab Med 45:143-8, 2021
   doi : 10.1016/j.cmi.2021.05.001
   (IF 2.7)
9. Precision medicine reaching out to the patients in allergology – a German-Japanese workshop report
   Pfaar O, Blumchen K, Boateng E, Hamelmann E, Jacob T, Krauss-Etschmann S, Nagase H, Nakajima S, Nakano T, Renz H, Sat S, Taube C, Tomohisa I, Wagenmann M, Werfel T, Worm M, Izuhara K
   Allergol. Select, 5: 1-18, 2021
   doi : 10.5414/ALX02234E
   (IF 5.8)
10. Physiology and pathology of eosinophils: Recent developments: Summary of the Focus Workshop Organized by DGAKI
    Renz H, Bachert C, Berek C, Hamelmann E, Levi-Schaffer F, Raap U, Simon HU, Ploetz S, Taube C, Valent P, Voehringer D, Werfel T, Zhang N, Ring J
    Scand J Immunol.e13032, 2021
    doi: 10.1111/sji.13032
    (IF 3.5)
11. Early life microbial exposures and allergy risks: opportunities for prevention
    Renz H, Skevaki C
    Nature Rev Immunol, 21(3):177-191, 2021
    doi: 10.1038/s41577-020-00420-y
    (IF 53.1)
12. SARS-CoV-2 infection and COVID-19 in asthmatics: a complex relationship
    Skevaki C, Karsonova A, Karaulov A, Fomina D, Xie M, Chinthrajah S, Nadeau KC, Renz H
    Immunol. 21:202-203, 2021
    doi: 10.1038/s41577-021-00516-z
    (IF 53.1)
13. Regulatory immune cells in idiopathic pulmonary fibrosis: Friends or foes
    van Geffen C, Deißler A, Quante M, Renz H, Hartl D, Kolahian S
    Frontiers Immunol, 12:6632032021, 2021
    doi :10.3389/fimmu.2021.663203
    (IF 8.786)
14. Spotlight on microRNAs in allergy and asthma
    Weidner J, Bartel S, Kılıç A, Zissler UM, Renz H, Schwarze J, Schmidt-Weber CB, Maes T, Rebane A, Krauss-Etschmann S, Rådinger M
    Allergy.76:1661-78, 2021
    doi: 10.1111/all.14646
    (IF 7.5)
15. Chronic myeloid leukemia – a model disease of the past, presence and future
    Kumar R, Miniciacchi VR, Krause DS
    Cells, 10 :117, 2021
    doi : 10.3390/cells10010117
    (IF 6.8)
16. Recent advances in understanding chronic myeloid leukemia – where do we stand
    Kumar R, Krause DS
    Faculty Reviews, 10(35), 2021
    doi : 10.3390/cells10010117
17. Evading eviction – leukemic stem cell squatters
    Krause DS
    Blood, 138(12) :1007-1008, 2021
    doi : 10.12703/r/10-35
    (IF 23.6)
18. Epidemiology and management of asthma and atopic dermatitis in Sub-Saharan Africa
    Skevaki C, Ngocho JS, Amour C, Schmid-Grendelmeier P, Mmbaga BT, Renz H
    J Allergy Clin Immunol., 148(6) :1378-1386, 2021
    doi : 10.1016/j.jaci.2021.10.019
    (IF 10.8)