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Dr. Isabelle C. Ridderbusch

Research Fellow · Systems Neuroscience in Psychiatry and Psychotherapy

Phone: +49 6421 58-65461

Rudolf-Bultmann-Straße 8
35033 Marburg

Research Interests

  • anxiety disorders & depression
  • fMRI & neural correlates of fear conditioning and extinction learning
  • genetic risk factors in mental disorders
  • psychotherapy research


2021 M.A. in Philosophy, University of Marburg
2020 PhD (Dr. rer. nat.) in Neuroscience, University of Marburg
2015 Diploma in Psychology, University of Marburg
2014 B.A. in Philosophy, University of Marburg

Affiliated Projects



Wroblewski, A., Hollandt, M., Yang, Y., Ridderbusch, I. C., Pietzner, A., Szeska, C., Lotze, M., Wittchen, H.-U., Heinig, I., Pittig, A., Arolt, V., Koelkebeck, K., Rothkopf, C. A., Adolph, D.,  Margraf, J., Lueken, U., Pauli, P., Herrmann, M. J., Winkler, M. H., Ströhle, A., Dannlowski, U., Kircher, T., Hamm, A. O., Straube, B.,  Richter, J. (2022). Sometimes I feel the fear of uncertainty: How intolerance of uncertainty and trait anxiety impact fear acquisition, extinction and the return of fear. International Journal of Psychophysiology, 181, 125-140.

Hollandt, M., Wroblewski, A., Yang, Y., Ridderbusch, I.C., Kircher, T., Hamm, A. O., Straube, B., Richter, J. (2020). Facilitating translational science in anxiety disorders by using an optimized extinction-learning paradigm with high content validity to exposure based therapy.   Translational Psychiatry, 10(1):110.

Ridderbusch, I.C., Richter, J., Yang, Y., Hoefler, M., Weber, H., Reif, A., Hamm, A., Pané-Farré C.A., Gerlach, A.L., Ströhle, A., Pfleiderer, B., Arolt, V., Wittchen, H.-U., Gloster, A., Lang, T., Helbig-Lang, S., Fehm, L., Pauli, P., Kircher, T., Lueken, U., & Straube, B. (2019). Association of rs7688285 allelic variation coding for GLRB with fear reactivity and exposure-based therapy in patients with panic disorder and agoraphobia. European Neuropsychopharmacology, 29(10):1138-1151.

Ridderbusch, I.C., Wroblewski, A. Yang, Y. Wittchen, H.-U., Ströhle, A., Hamm, A., Richter, J., Hollandt, M., Arolt, V., Margraf, J., Herrmann, M., Kircher, T., Straube, B. (2021). Neural adaptation of cingulate and insular activity during delayed fear extinction: A replicable pattern across assessment sites and repeated measurements. NeuroImage, 237:118157.

Ridderbusch, I.C., Yang, Y., Weber, H., Reif, A., Herterich, S., Ströhle, A., Pfleiderer, B., Arolt, V., Wittchen, H.-U., Lueken, U., Kircher, T., Straube, B. (2020). Neural correlates of NOS1 ex1f-VNTR allelic variation in panic disorder and agoraphobia during fear conditioning and extinction in fMRI. Neuroimage: Clinical, 27: 102268.